371 related articles for article (PubMed ID: 35026048)
21. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity.
Kramer NJ; Haney MS; Morgens DW; Jovičić A; Couthouis J; Li A; Ousey J; Ma R; Bieri G; Tsui CK; Shi Y; Hertz NT; Tessier-Lavigne M; Ichida JK; Bassik MC; Gitler AD
Nat Genet; 2018 Apr; 50(4):603-612. PubMed ID: 29507424
[TBL] [Abstract][Full Text] [Related]
22. Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD.
Westergard T; Jensen BK; Wen X; Cai J; Kropf E; Iacovitti L; Pasinelli P; Trotti D
Cell Rep; 2016 Oct; 17(3):645-652. PubMed ID: 27732842
[TBL] [Abstract][Full Text] [Related]
23. The most prevalent genetic cause of ALS-FTD, C9orf72 synergizes the toxicity of ATXN2 intermediate polyglutamine repeats through the autophagy pathway.
Ciura S; Sellier C; Campanari ML; Charlet-Berguerand N; Kabashi E
Autophagy; 2016 Aug; 12(8):1406-8. PubMed ID: 27245636
[TBL] [Abstract][Full Text] [Related]
24. ER-mitochondria signaling regulates autophagy.
Gomez-Suaga P; Paillusson S; Miller CCJ
Autophagy; 2017 Jul; 13(7):1250-1251. PubMed ID: 28548902
[TBL] [Abstract][Full Text] [Related]
25. Glial Cell Dysfunction in
Ghasemi M; Keyhanian K; Douthwright C
Cells; 2021 Jan; 10(2):. PubMed ID: 33525344
[TBL] [Abstract][Full Text] [Related]
26. C9orf72 Gene Expression in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.
Shpilyukova YA; Fedotova EY; Abramycheva NY; Kochergin IA; Zakroyshchikova IV; Zakharova MN; Illarioshkin SN
Bull Exp Biol Med; 2020 Sep; 169(5):673-676. PubMed ID: 32990847
[TBL] [Abstract][Full Text] [Related]
27. Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
Boivin M; Pfister V; Gaucherot A; Ruffenach F; Negroni L; Sellier C; Charlet-Berguerand N
EMBO J; 2020 Feb; 39(4):e100574. PubMed ID: 31930538
[TBL] [Abstract][Full Text] [Related]
28. Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72.
Zhu Q; Jiang J; Gendron TF; McAlonis-Downes M; Jiang L; Taylor A; Diaz Garcia S; Ghosh Dastidar S; Rodriguez MJ; King P; Zhang Y; La Spada AR; Xu H; Petrucelli L; Ravits J; Da Cruz S; Lagier-Tourenne C; Cleveland DW
Nat Neurosci; 2020 May; 23(5):615-624. PubMed ID: 32284607
[TBL] [Abstract][Full Text] [Related]
29. A cell-penetrant peptide blocking
Castelli LM; Lin YH; Sanchez-Martinez A; Gül A; Mohd Imran K; Higginbottom A; Upadhyay SK; Márkus NM; Rua Martins R; Cooper-Knock J; Montmasson C; Cohen R; Walton A; Bauer CS; De Vos KJ; Mead RJ; Azzouz M; Dominguez C; Ferraiuolo L; Shaw PJ; Whitworth AJ; Hautbergue GM
Sci Transl Med; 2023 Mar; 15(685):eabo3823. PubMed ID: 36857431
[TBL] [Abstract][Full Text] [Related]
30. Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit.
Sattler R; Traynor BJ; Robertson J; Van Den Bosch L; Barmada SJ; Svendsen CN; Disney MD; Gendron TF; Wong PC; Turner MR; Boxer A; Babu S; Benatar M; Kurnellas M; Rohrer JD; Donnelly CJ; Bustos LM; Van Keuren-Jensen K; Dacks PA; Sabbagh MN;
Neurol Ther; 2023 Dec; 12(6):1821-1843. PubMed ID: 37847372
[TBL] [Abstract][Full Text] [Related]
31. Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins.
Darling AL; Breydo L; Rivas EG; Gebru NT; Zheng D; Baker JD; Blair LJ; Dickey CA; Koren J; Uversky VN
Int J Biol Macromol; 2019 Apr; 127():136-145. PubMed ID: 30639592
[TBL] [Abstract][Full Text] [Related]
32. Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress.
Westergard T; McAvoy K; Russell K; Wen X; Pang Y; Morris B; Pasinelli P; Trotti D; Haeusler A
EMBO Mol Med; 2019 Feb; 11(2):. PubMed ID: 30617154
[TBL] [Abstract][Full Text] [Related]
33. Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD.
Starr A; Sattler R
Brain Res; 2018 Aug; 1693(Pt A):98-108. PubMed ID: 29453960
[TBL] [Abstract][Full Text] [Related]
34. Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia.
Jiang J; Ravits J
Neurotherapeutics; 2019 Oct; 16(4):1115-1132. PubMed ID: 31667754
[TBL] [Abstract][Full Text] [Related]
35. The progress in
Jiang L; Zhang T; Lu K; Qi S
Small GTPases; 2022 Jan; 13(1):56-76. PubMed ID: 33663328
[TBL] [Abstract][Full Text] [Related]
36. PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD.
Pilotto F; Schmitz A; Maharjan N; Diab R; Odriozola A; Tripathi P; Yamoah A; Scheidegger O; Oestmann A; Dennys CN; Sinha Ray S; Rodrigo R; Kolb S; Aronica E; Di Santo S; Widmer HR; Charlet-Berguerand N; Selvaraj BT; Chandran S; Meyer K; Zuber B; Goswami A; Weis J; Saxena S
Acta Neuropathol; 2022 Nov; 144(5):939-966. PubMed ID: 36121477
[TBL] [Abstract][Full Text] [Related]
37. Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.
Yin S; Lopez-Gonzalez R; Kunz RC; Gangopadhyay J; Borufka C; Gygi SP; Gao FB; Reed R
Cell Rep; 2017 Jun; 19(11):2244-2256. PubMed ID: 28614712
[TBL] [Abstract][Full Text] [Related]
38. C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis.
Rohrer JD; Isaacs AM; Mizielinska S; Mead S; Lashley T; Wray S; Sidle K; Fratta P; Orrell RW; Hardy J; Holton J; Revesz T; Rossor MN; Warren JD
Lancet Neurol; 2015 Mar; 14(3):291-301. PubMed ID: 25638642
[TBL] [Abstract][Full Text] [Related]
39. Translation of dipeptide repeat proteins in
Sonobe Y; Lee S; Krishnan G; Gu Y; Kwon DY; Gao FB; Roos RP; Kratsios P
Elife; 2023 Sep; 12():. PubMed ID: 37675986
[TBL] [Abstract][Full Text] [Related]
40. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
Peters OM; Cabrera GT; Tran H; Gendron TF; McKeon JE; Metterville J; Weiss A; Wightman N; Salameh J; Kim J; Sun H; Boylan KB; Dickson D; Kennedy Z; Lin Z; Zhang YJ; Daughrity L; Jung C; Gao FB; Sapp PC; Horvitz HR; Bosco DA; Brown SP; de Jong P; Petrucelli L; Mueller C; Brown RH
Neuron; 2015 Dec; 88(5):902-909. PubMed ID: 26637797
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]