206 related articles for article (PubMed ID: 35045984)
1. Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy.
Hong Z; Liu T; Wan L; Fa P; Kumar P; Cao Y; Prasad CB; Qiu Z; Liu J; Wang H; Li Z; Wang QE; Guo P; Guo D; Yilmaz AS; Lu L; Papandreou I; Jacob NK; Yan C; Zhang X; She QB; Ma Z; Zhang J
Cancer Res; 2022 Apr; 82(7):1298-1312. PubMed ID: 35045984
[TBL] [Abstract][Full Text] [Related]
2. Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target.
Liu D; Wong CC; Fu L; Chen H; Zhao L; Li C; Zhou Y; Zhang Y; Xu W; Yang Y; Wu B; Cheng G; Lai PB; Wong N; Sung JJY; Yu J
Sci Transl Med; 2018 Apr; 10(437):. PubMed ID: 29669855
[TBL] [Abstract][Full Text] [Related]
3. Squalene epoxidase promotes the proliferation and metastasis of lung squamous cell carcinoma cells though extracellular signal-regulated kinase signaling.
Ge H; Zhao Y; Shi X; Tan Z; Chi X; He M; Jiang G; Ji L; Li H
Thorac Cancer; 2019 Mar; 10(3):428-436. PubMed ID: 30734525
[TBL] [Abstract][Full Text] [Related]
4. Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer.
Brown DN; Caffa I; Cirmena G; Piras D; Garuti A; Gallo M; Alberti S; Nencioni A; Ballestrero A; Zoppoli G
Sci Rep; 2016 Jan; 6():19435. PubMed ID: 26777065
[TBL] [Abstract][Full Text] [Related]
5. Squalene epoxidase-induced cholesteryl ester accumulation promotes nasopharyngeal carcinoma development by activating PI3K/AKT signaling.
Li L; Zhang Q; Wang X; Li Y; Xie H; Chen X
Cancer Sci; 2020 Jul; 111(7):2275-2283. PubMed ID: 32314495
[TBL] [Abstract][Full Text] [Related]
6. Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase.
Padyana AK; Gross S; Jin L; Cianchetta G; Narayanaswamy R; Wang F; Wang R; Fang C; Lv X; Biller SA; Dang L; Mahoney CE; Nagaraja N; Pirman D; Sui Z; Popovici-Muller J; Smolen GA
Nat Commun; 2019 Jan; 10(1):97. PubMed ID: 30626872
[TBL] [Abstract][Full Text] [Related]
7. Squalene Epoxidase Metabolic Dependency Is a Targetable Vulnerability in Castration-Resistant Prostate Cancer.
Shangguan X; Ma Z; Yu M; Ding J; Xue W; Qi J
Cancer Res; 2022 Sep; 82(17):3032-3044. PubMed ID: 35767703
[TBL] [Abstract][Full Text] [Related]
8. Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1-mediated MAPK signaling.
He L; Li H; Pan C; Hua Y; Peng J; Zhou Z; Zhao Y; Lin M
Cancer Commun (Lond); 2021 Aug; 41(8):726-746. PubMed ID: 34268906
[TBL] [Abstract][Full Text] [Related]
9. SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.
Xu R; Song J; Ruze R; Chen Y; Yin X; Wang C; Zhao Y
Cell Death Dis; 2023 Aug; 14(8):497. PubMed ID: 37542052
[TBL] [Abstract][Full Text] [Related]
10. Reduction of Squalene Epoxidase by Cholesterol Accumulation Accelerates Colorectal Cancer Progression and Metastasis.
Jun SY; Brown AJ; Chua NK; Yoon JY; Lee JJ; Yang JO; Jang I; Jeon SJ; Choi TI; Kim CH; Kim NS
Gastroenterology; 2021 Mar; 160(4):1194-1207.e28. PubMed ID: 32946903
[TBL] [Abstract][Full Text] [Related]
11. Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression.
Jiang H; Tang E; Chen Y; Liu H; Zhao Y; Lin M; He L
Cancer Sci; 2022 Mar; 113(3):971-985. PubMed ID: 34939274
[TBL] [Abstract][Full Text] [Related]
12. Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
Zhang Z; Wu W; Jiao H; Chen Y; Ji X; Cao J; Yin F; Yin W
Br J Pharmacol; 2023 Jun; 180(12):1562-1581. PubMed ID: 36581319
[TBL] [Abstract][Full Text] [Related]
13. Squalene epoxidase/SQLE is a candidate target for treatment of colorectal cancers with
Du Y; Rokavec M; Hermeking H
Int J Biol Sci; 2023; 19(13):4103-4122. PubMed ID: 37705742
[TBL] [Abstract][Full Text] [Related]
14. Squalene Epoxidase Induces Nonalcoholic Steatohepatitis Via Binding to Carbonic Anhydrase III and is a Therapeutic Target.
Liu D; Wong CC; Zhou Y; Li C; Chen H; Ji F; Go MYY; Wang F; Su H; Wei H; Cai Z; Wong N; Wong VWS; Yu J
Gastroenterology; 2021 Jun; 160(7):2467-2482.e3. PubMed ID: 33647280
[TBL] [Abstract][Full Text] [Related]
15. Squalene epoxidase, located on chromosome 8q24.1, is upregulated in 8q+ breast cancer and indicates poor clinical outcome in stage I and II disease.
Helms MW; Kemming D; Pospisil H; Vogt U; Buerger H; Korsching E; Liedtke C; Schlotter CM; Wang A; Chan SY; Brandt BH
Br J Cancer; 2008 Sep; 99(5):774-80. PubMed ID: 18728668
[TBL] [Abstract][Full Text] [Related]
16. Identifying squalene epoxidase as a metabolic vulnerability in high-risk osteosarcoma using an artificial intelligence-derived prognostic index.
Wang Y; Ma X; Xu E; Huang Z; Yang C; Zhu K; Dong Y; Zhang C
Clin Transl Med; 2024 Feb; 14(2):e1586. PubMed ID: 38372422
[TBL] [Abstract][Full Text] [Related]
17. Preclinical toxicology profile of squalene epoxidase inhibitors.
Nagaraja R; Olaharski A; Narayanaswamy R; Mahoney C; Pirman D; Gross S; Roddy TP; Popovici-Muller J; Smolen GA; Silverman L
Toxicol Appl Pharmacol; 2020 Aug; 401():115103. PubMed ID: 32522582
[TBL] [Abstract][Full Text] [Related]
18. Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis.
Li C; Wang Y; Liu D; Wong CC; Coker OO; Zhang X; Liu C; Zhou Y; Liu Y; Kang W; To KF; Sung JJ; Yu J
Gut; 2022 Nov; 71(11):2253-2265. PubMed ID: 35232776
[TBL] [Abstract][Full Text] [Related]
19. Squalene Epoxidase: Its Regulations and Links with Cancers.
Zhang L; Cao Z; Hong Y; He H; Chen L; Yu Z; Gao Y
Int J Mol Sci; 2024 Mar; 25(7):. PubMed ID: 38612682
[TBL] [Abstract][Full Text] [Related]
20. Squalene epoxidase facilitates cervical cancer progression by modulating tumor protein p53 signaling pathway.
Guo M; Qiao Y; Lu Y; Zhu L; Zheng L
J Obstet Gynaecol Res; 2023 May; 49(5):1383-1392. PubMed ID: 36843235
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]