These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 35046963)

  • 1. Structural Basis of Antibody Conformation and Stability Modulation by Framework Somatic Hypermutation.
    Sheng Z; Bimela JS; Katsamba PS; Patel SD; Guo Y; Zhao H; Guo Y; Kwong PD; Shapiro L
    Front Immunol; 2021; 12():811632. PubMed ID: 35046963
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies.
    Hwang JK; Wang C; Du Z; Meyers RM; Kepler TB; Neuberg D; Kwong PD; Mascola JR; Joyce MG; Bonsignori M; Haynes BF; Yeap LS; Alt FW
    Proc Natl Acad Sci U S A; 2017 Aug; 114(32):8614-8619. PubMed ID: 28747530
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection.
    Chan KW; Pan R; Costa M; Gorny MK; Wang S; Lu S; Kong XP
    J Virol; 2018 Sep; 92(18):. PubMed ID: 29997214
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Effects of Framework Mutations at the Variable Domain Interface on Antibody Affinity Maturation in an HIV-1 Broadly Neutralizing Antibody Lineage.
    Zhou JO; Zaidi HA; Ton T; Fera D
    Front Immunol; 2020; 11():1529. PubMed ID: 32765530
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.
    Davenport TM; Gorman J; Joyce MG; Zhou T; Soto C; Guttman M; Moquin S; Yang Y; Zhang B; Doria-Rose NA; Hu SL; Mascola JR; Kwong PD; Lee KK
    Structure; 2016 Aug; 24(8):1346-1357. PubMed ID: 27477385
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A general approach to antibody thermostabilization.
    McConnell AD; Zhang X; Macomber JL; Chau B; Sheffer JC; Rahmanian S; Hare E; Spasojevic V; Horlick RA; King DJ; Bowers PM
    MAbs; 2014; 6(5):1274-82. PubMed ID: 25517312
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies.
    Bowers PM; Boyle WJ; Damoiseaux R
    Methods Mol Biol; 2018; 1827():479-489. PubMed ID: 30196512
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation.
    Wang F; Sen S; Zhang Y; Ahmad I; Zhu X; Wilson IA; Smider VV; Magliery TJ; Schultz PG
    Proc Natl Acad Sci U S A; 2013 Mar; 110(11):4261-6. PubMed ID: 23440204
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Large-scale analysis of somatic hypermutations in antibodies reveals which structural regions, positions and amino acids are modified to improve affinity.
    Burkovitz A; Sela-Culang I; Ofran Y
    FEBS J; 2014 Jan; 281(1):306-19. PubMed ID: 24279419
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies.
    Kepler TB; Liao HX; Alam SM; Bhaskarabhatla R; Zhang R; Yandava C; Stewart S; Anasti K; Kelsoe G; Parks R; Lloyd KE; Stolarchuk C; Pritchett J; Solomon E; Friberg E; Morris L; Karim SS; Cohen MS; Walter E; Moody MA; Wu X; Altae-Tran HR; Georgiev IS; Kwong PD; Boyd SD; Fire AZ; Mascola JR; Haynes BF
    Cell Host Microbe; 2014 Sep; 16(3):304-13. PubMed ID: 25211073
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural Features of Broadly Neutralizing Antibodies and Rational Design of Vaccine.
    Zhou T; Xu K
    Adv Exp Med Biol; 2018; 1075():73-95. PubMed ID: 30030790
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
    Fera D; Schmidt AG; Haynes BF; Gao F; Liao HX; Kepler TB; Harrison SC
    Proc Natl Acad Sci U S A; 2014 Jul; 111(28):10275-80. PubMed ID: 24982157
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
    Doria-Rose NA; Schramm CA; Gorman J; Moore PL; Bhiman JN; DeKosky BJ; Ernandes MJ; Georgiev IS; Kim HJ; Pancera M; Staupe RP; Altae-Tran HR; Bailer RT; Crooks ET; Cupo A; Druz A; Garrett NJ; Hoi KH; Kong R; Louder MK; Longo NS; McKee K; Nonyane M; O'Dell S; Roark RS; Rudicell RS; Schmidt SD; Sheward DJ; Soto C; Wibmer CK; Yang Y; Zhang Z; ; Mullikin JC; Binley JM; Sanders RW; Wilson IA; Moore JP; Ward AB; Georgiou G; Williamson C; Abdool Karim SS; Morris L; Kwong PD; Shapiro L; Mascola JR
    Nature; 2014 May; 509(7498):55-62. PubMed ID: 24590074
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
    Garces F; Lee JH; de Val N; de la Pena AT; Kong L; Puchades C; Hua Y; Stanfield RL; Burton DR; Moore JP; Sanders RW; Ward AB; Wilson IA
    Immunity; 2015 Dec; 43(6):1053-63. PubMed ID: 26682982
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased Epitope Complexity Correlated with Antibody Affinity Maturation and a Novel Binding Mode Revealed by Structures of Rabbit Antibodies against the Third Variable Loop (V3) of HIV-1 gp120.
    Pan R; Qin Y; Banasik M; Lees W; Shepherd AJ; Cho MW; Kong XP
    J Virol; 2018 Apr; 92(7):. PubMed ID: 29343576
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.
    Scheid JF; Mouquet H; Ueberheide B; Diskin R; Klein F; Oliveira TY; Pietzsch J; Fenyo D; Abadir A; Velinzon K; Hurley A; Myung S; Boulad F; Poignard P; Burton DR; Pereyra F; Ho DD; Walker BD; Seaman MS; Bjorkman PJ; Chait BT; Nussenzweig MC
    Science; 2011 Sep; 333(6049):1633-7. PubMed ID: 21764753
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Improvement in affinity and HIV-1 neutralization by somatic mutation in the heavy chain first complementarity-determining region of antibodies triggered by HIV-1 infection.
    Torán JL; Sánchez-Pulido L; Kremer L; del Real G; Valencia A; Martínez-A C
    Eur J Immunol; 2001 Jan; 31(1):128-37. PubMed ID: 11169446
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection.
    Sheng Z; Schramm CA; Connors M; Morris L; Mascola JR; Kwong PD; Shapiro L
    PLoS Comput Biol; 2016 May; 12(5):e1004940. PubMed ID: 27191167
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline.
    Georgiev IS; Rudicell RS; Saunders KO; Shi W; Kirys T; McKee K; O'Dell S; Chuang GY; Yang ZY; Ofek G; Connors M; Mascola JR; Nabel GJ; Kwong PD
    J Immunol; 2014 Feb; 192(3):1100-1106. PubMed ID: 24391217
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human Immunodeficiency Virus Tat Protein Aids V Region Somatic Hypermutation in Human B Cells.
    Wang X; Duan Z; Yu G; Fan M; Scharff MD
    mBio; 2018 Apr; 9(2):. PubMed ID: 29666292
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.