BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 35056725)

  • 1. Synthesis and Biological Activity of 3-(Heteroaryl)quinolin-2(1
    Larghi EL; Bruneau A; Sauvage F; Alami M; Vergnaud-Gauduchon J; Messaoudi S
    Molecules; 2022 Jan; 27(2):. PubMed ID: 35056725
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and biological activity of 6BrCaQ as an inhibitor of the Hsp90 protein folding machinery.
    Audisio D; Messaoudi S; Cegielkowski L; Peyrat JF; Brion JD; Methy-Gonnot D; Radanyi C; Renoir JM; Alami M
    ChemMedChem; 2011 May; 6(5):804-15. PubMed ID: 21374821
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1.
    Mathieu C; Chamayou Q; Hyen Luong TT; Naud D; Mahuteau-Betzer F; Alami M; Fattal E; Messaoudi S; Vergnaud-Gauduchon J
    Eur J Med Chem; 2022 Feb; 229():114052. PubMed ID: 34952432
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response.
    Armstrong HK; Koay YC; Irani S; Das R; Nassar ZD; ; Selth LA; Centenera MM; McAlpine SR; Butler LM
    Prostate; 2016 Dec; 76(16):1546-1559. PubMed ID: 27526951
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Formulation and in vitro efficacy of liposomes containing the Hsp90 inhibitor 6BrCaQ in prostate cancer cells.
    Sauvage F; Franzè S; Bruneau A; Alami M; Denis S; Nicolas V; Lesieur S; Legrand FX; Barratt G; Messaoudi S; Vergnaud-Gauduchon J
    Int J Pharm; 2016 Feb; 499(1-2):101-109. PubMed ID: 26721724
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pd-Catalyzed Coupling of Bromo-N-(β-glucopyranpsyl)quinolin-2-ones with Amides: Synthesis of N-glucosyl-6BrCaQ Conjugates with Potent Anticancer Activity.
    Redjdal W; Benmahdjoub S; Luong TTH; Benmerad B; Le Bideau F; Vergnaud J; Messaoudi S
    ChemMedChem; 2024 Apr; ():e202400195. PubMed ID: 38687188
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and antiproliferative activity of novobiocin analogues as potential hsp90 inhibitors.
    Audisio D; Methy-Gonnot D; Radanyi C; Renoir JM; Denis S; Sauvage F; Vergnaud-Gauduchon J; Brion JD; Messaoudi S; Alami M
    Eur J Med Chem; 2014 Aug; 83():498-507. PubMed ID: 24992077
    [TBL] [Abstract][Full Text] [Related]  

  • 8. X66, a novel N-terminal heat shock protein 90 inhibitor, exerts antitumor effects without induction of heat shock response.
    Zhao Z; Zhu J; Quan H; Wang G; Li B; Zhu W; Xie C; Lou L
    Oncotarget; 2016 May; 7(20):29648-63. PubMed ID: 27105490
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery and Bioevaluation of Novel Pyrazolopyrimidine Analogs as Competitive Hsp90 Inhibitors Through Shape-Based Similarity Screening.
    Xu XL; Sun HP; Liu F; Jia JM; Guo XK; Pan Y; Huang HZ; Zhang XJ; You QD
    Mol Inform; 2014 Apr; 33(4):293-306. PubMed ID: 27485776
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tubocapsenolide A, a novel withanolide, inhibits proliferation and induces apoptosis in MDA-MB-231 cells by thiol oxidation of heat shock proteins.
    Chen WY; Chang FR; Huang ZY; Chen JH; Wu YC; Wu CC
    J Biol Chem; 2008 Jun; 283(25):17184-93. PubMed ID: 18442981
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.
    He H; Zatorska D; Kim J; Aguirre J; Llauger L; She Y; Wu N; Immormino RM; Gewirth DT; Chiosis G
    J Med Chem; 2006 Jan; 49(1):381-90. PubMed ID: 16392823
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel 1,6-naphthyridin-2(1H)-ones as potential anticancer agents targeting Hsp90.
    Montoir D; Barillé-Nion S; Tonnerre A; Juin P; Duflos M; Bazin MA
    Eur J Med Chem; 2016 Aug; 119():17-33. PubMed ID: 27153346
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
    Massey AJ; Williamson DS; Browne H; Murray JB; Dokurno P; Shaw T; Macias AT; Daniels Z; Geoffroy S; Dopson M; Lavan P; Matassova N; Francis GL; Graham CJ; Parsons R; Wang Y; Padfield A; Comer M; Drysdale MJ; Wood M
    Cancer Chemother Pharmacol; 2010 Aug; 66(3):535-45. PubMed ID: 20012863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
    El-Shafey HW; Gomaa RM; El-Messery SM; Goda FE
    Bioorg Med Chem Lett; 2020 Aug; 30(15):127281. PubMed ID: 32527460
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation.
    Blagg BS; Kerr TD
    Med Res Rev; 2006 May; 26(3):310-38. PubMed ID: 16385472
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hsp90 inhibitors identified from a library of novobiocin analogues.
    Yu XM; Shen G; Neckers L; Blake H; Holzbeierlein J; Cronk B; Blagg BS
    J Am Chem Soc; 2005 Sep; 127(37):12778-9. PubMed ID: 16159253
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cruentaren A binds F1F0 ATP synthase to modulate the Hsp90 protein folding machinery.
    Hall JA; Kusuma BR; Brandt GE; Blagg BS
    ACS Chem Biol; 2014 Apr; 9(4):976-85. PubMed ID: 24450340
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells.
    Matthews SB; Vielhauer GA; Manthe CA; Chaguturu VK; Szabla K; Matts RL; Donnelly AC; Blagg BS; Holzbeierlein JM
    Prostate; 2010 Jan; 70(1):27-36. PubMed ID: 19739131
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma.
    Mohamady S; Ismail MI; Mogheith SM; Attia YM; Taylor SD
    Bioorg Chem; 2020 Jan; 94():103433. PubMed ID: 31785857
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.
    Kasibhatla SR; Hong K; Biamonte MA; Busch DJ; Karjian PL; Sensintaffar JL; Kamal A; Lough RE; Brekken J; Lundgren K; Grecko R; Timony GA; Ran Y; Mansfield R; Fritz LC; Ulm E; Burrows FJ; Boehm MF
    J Med Chem; 2007 Jun; 50(12):2767-78. PubMed ID: 17488003
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.