BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 35059869)

  • 1. The inhibition of Panc1 cancer cells invasion by hAMSCs secretome through suppression of tyrosine phosphorylation of SGK223 (at Y411 site), c-Src (at Y416, Y530 sites), AKT activity, and JAK1/Stat3 signaling.
    Safari F; Shafiee Nejad N; Aghaei Nejad A
    Med Oncol; 2022 Jan; 39(3):28. PubMed ID: 35059869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluating the in vitro therapeutic effects of human amniotic mesenchymal stromal cells on MiaPaca2 pancreatic cancer cells using 2D and 3D cell culture model.
    Rahmani Z; Safari F
    Tissue Cell; 2021 Feb; 68():101479. PubMed ID: 33383360
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling.
    Tactacan CM; Phua YW; Liu L; Zhang L; Humphrey ES; Cowley M; Pinese M; Biankin AV; Daly RJ
    Mol Cancer; 2015 Jul; 14():139. PubMed ID: 26215634
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro evaluation of autophagy and cell death induction in Panc1 pancreatic cancer by secretome of hAMSCs through downregulation of p-AKT/p-mTOR and upregulation of p-AMPK/ULK1 signal transduction pathways.
    Safari F; Dadvar F
    Tissue Cell; 2023 Oct; 84():102160. PubMed ID: 37482027
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potential therapeutic effects of hAMSCs secretome on Panc1 pancreatic cancer cells through downregulation of SgK269, E-cadherin, vimentin, and snail expression.
    Alidoust Saharkhiz Lahiji M; Safari F
    Biologicals; 2022 Apr; 76():24-30. PubMed ID: 35216916
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src.
    Jaganathan S; Yue P; Turkson J
    J Pharmacol Exp Ther; 2010 May; 333(2):373-81. PubMed ID: 20100905
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evaluation of SgK269 expression in colon cancer patients and the effects of hAMSCs secretome on tumor invasion through SgK269/c-Src/p-P130Cas/p-Paxillin/p-ERK1/2 signaling pathway in HT-29 colon cancer cells.
    Safari F; Ansari Dogaheh F; Dadashi H
    3 Biotech; 2023 Nov; 13(11):346. PubMed ID: 37744286
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Downregulation of Pinkbar/pAKT and MMP2/MMP9 Expression in MDA-MB-231 Breast Cancer Cells as Potential Targets in Cancer Therapy by hAMSCs Secretome.
    Shakery T; Safari F
    Cells Tissues Organs; 2023; 212(2):155-163. PubMed ID: 34695828
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Antitumor Activity of hAMSCs Secretome in HT-29 Colon Cancer Cells Through Downregulation of EGFR/c-Src/IRTKS Expression and p38/ERK1/2 Phosphorylation.
    Ebadi Zavieh S; Safari F
    Cell Biochem Biophys; 2022 Jun; 80(2):395-402. PubMed ID: 35150389
    [TBL] [Abstract][Full Text] [Related]  

  • 10. JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling.
    Song L; Rawal B; Nemeth JA; Haura EB
    Mol Cancer Ther; 2011 Mar; 10(3):481-94. PubMed ID: 21216930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity.
    Zhang Y; Turkson J; Carter-Su C; Smithgall T; Levitzki A; Kraker A; Krolewski JJ; Medveczky P; Jove R
    J Biol Chem; 2000 Aug; 275(32):24935-44. PubMed ID: 10823829
    [TBL] [Abstract][Full Text] [Related]  

  • 12. C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility.
    Senda Y; Murata-Kamiya N; Hatakeyama M
    Cancer Sci; 2016 Jul; 107(7):972-80. PubMed ID: 27116701
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways.
    Neilson LM; Zhu J; Xie J; Malabarba MG; Sakamoto K; Wagner KU; Kirken RA; Rui H
    Mol Endocrinol; 2007 Sep; 21(9):2218-32. PubMed ID: 17550976
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Blockage of STAT3 Signaling Pathway by Morusin Induces Apoptosis and Inhibits Invasion in Human Pancreatic Tumor Cells.
    Kim C; Kim JH; Oh EY; Nam D; Lee SG; Lee J; Kim SH; Shim BS; Ahn KS
    Pancreas; 2016 Mar; 45(3):409-19. PubMed ID: 26646273
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pyk2 amplifies epidermal growth factor and c-Src-induced Stat3 activation.
    Shi CS; Kehrl JH
    J Biol Chem; 2004 Apr; 279(17):17224-31. PubMed ID: 14963038
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk.
    Van Slyke P; Coll ML; Master Z; Kim H; Filmus J; Dumont DJ
    Mol Cell Biol; 2005 May; 25(9):3831-41. PubMed ID: 15831486
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways.
    Gao J; Xia R; Chen J; Gao J; Luo X; Ke C; Ren C; Li J; Mi Y
    Aging (Albany NY); 2020 Apr; 12(7):6240-6259. PubMed ID: 32276266
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F; Gendo C; Eck M; Schmitz J; Grimm C; Anhuf D; Kerr IM; Heinrich PC
    Biochem J; 1998 Nov; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tyrosine 416 is phosphorylated in the closed, repressed conformation of c-Src.
    Irtegun S; Wood RJ; Ormsby AR; Mulhern TD; Hatters DM
    PLoS One; 2013; 8(7):e71035. PubMed ID: 23923048
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases.
    Liu L; Phua YW; Lee RS; Ma X; Jenkins Y; Novy K; Humphrey ES; Chan H; Shearer R; Ong PC; Dai W; Saunders DN; Lucet IS; Daly RJ
    J Biol Chem; 2016 Oct; 291(41):21571-21583. PubMed ID: 27531744
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.