180 related articles for article (PubMed ID: 35061330)
1. Covalent Fragment Screening Identifies Rgl2 RalGEF Cysteine for Targeted Covalent Inhibition of Ral GTPase Activation.
Bum-Erdene K; Ghozayel MK; Xu D; Meroueh SO
ChemMedChem; 2022 Mar; 17(6):e202100750. PubMed ID: 35061330
[TBL] [Abstract][Full Text] [Related]
2. Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases.
Bum-Erdene K; Liu D; Gonzalez-Gutierrez G; Ghozayel MK; Xu D; Meroueh SO
Proc Natl Acad Sci U S A; 2020 Mar; 117(13):7131-7139. PubMed ID: 32179690
[TBL] [Abstract][Full Text] [Related]
3. Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms.
Vigil D; Martin TD; Williams F; Yeh JJ; Campbell SL; Der CJ
J Biol Chem; 2010 Nov; 285(45):34729-40. PubMed ID: 20801877
[TBL] [Abstract][Full Text] [Related]
4. Covalent Fragment Inhibits RhoA Activation by Guanine Exchange Factors.
Hussain MS; Liu D; Alilain WJ; Meroueh SO
ACS Chem Neurosci; 2023 Jul; 14(14):2509-2516. PubMed ID: 37382289
[TBL] [Abstract][Full Text] [Related]
5. Exploring Covalent Bond Formation at Tyr-82 for Inhibition of Ral GTPase Activation.
Landgraf AD; Yeh IJ; Ghozayel MK; Bum-Erdene K; Gonzalez-Gutierrez G; Meroueh SO
ChemMedChem; 2023 Aug; 18(16):e202300272. PubMed ID: 37269475
[TBL] [Abstract][Full Text] [Related]
6. RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases.
O Santos A; Parrini MC; Camonis J
PLoS One; 2016; 11(5):e0154840. PubMed ID: 27149377
[TBL] [Abstract][Full Text] [Related]
7. p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.
Gotoh T; Cai D; Tian X; Feig LA; Lerner A
J Biol Chem; 2000 Sep; 275(39):30118-23. PubMed ID: 10896938
[TBL] [Abstract][Full Text] [Related]
8. The ral exchange factor rgl2 promotes cardiomyocyte survival and inhibits cardiac fibrosis.
Scotland RL; Allen L; Hennings LJ; Post GR; Post SR
PLoS One; 2013; 8(9):e73599. PubMed ID: 24069211
[TBL] [Abstract][Full Text] [Related]
9. Parallel Rap1>RalGEF>Ral and Ras signals sculpt the C. elegans nervous system.
Mardick JI; Rasmussen NR; Wightman B; Reiner DJ
Dev Biol; 2021 Sep; 477():37-48. PubMed ID: 33991533
[TBL] [Abstract][Full Text] [Related]
10. RalGDS family members couple Ras to Ral signalling and that's not all.
Ferro E; Trabalzini L
Cell Signal; 2010 Dec; 22(12):1804-10. PubMed ID: 20478380
[TBL] [Abstract][Full Text] [Related]
11. Ras-dependent activation of the small GTPase Ral.
Wolthuis RM; Zwartkruis F; Moen TC; Bos JL
Curr Biol; 1998 Apr; 8(8):471-4. PubMed ID: 9550702
[TBL] [Abstract][Full Text] [Related]
12. Ral-specific guanine nucleotide exchange factor activity opposes other Ras effectors in PC12 cells by inhibiting neurite outgrowth.
Goi T; Rusanescu G; Urano T; Feig LA
Mol Cell Biol; 1999 Mar; 19(3):1731-41. PubMed ID: 10022860
[TBL] [Abstract][Full Text] [Related]
13. G-protein binding features and regulation of the RalGDS family member, RGL2.
Ferro E; Magrini D; Guazzi P; Fischer TH; Pistolesi S; Pogni R; White GC; Trabalzini L
Biochem J; 2008 Oct; 415(1):145-54. PubMed ID: 18540861
[TBL] [Abstract][Full Text] [Related]
14. Ras-dependent regulation of c-Jun phosphorylation is mediated by the Ral guanine nucleotide exchange factor-Ral pathway.
de Ruiter ND; Wolthuis RM; van Dam H; Burgering BM; Bos JL
Mol Cell Biol; 2000 Nov; 20(22):8480-8. PubMed ID: 11046144
[TBL] [Abstract][Full Text] [Related]
15. Ras-independent activation of Ral by a Ca(2+)-dependent pathway.
Hofer F; Berdeaux R; Martin GS
Curr Biol; 1998 Jul; 8(14):839-42. PubMed ID: 9663394
[TBL] [Abstract][Full Text] [Related]
16. Localization of RalB signaling at endomembrane compartments and its modulation by autophagy.
Singh MK; Martin APJ; Joffre C; Zago G; Camonis J; Coppey M; Parrini MC
Sci Rep; 2019 Jun; 9(1):8910. PubMed ID: 31222145
[TBL] [Abstract][Full Text] [Related]
17. Ral small GTPase signaling and oncogenesis: More than just 15minutes of fame.
Gentry LR; Martin TD; Reiner DJ; Der CJ
Biochim Biophys Acta; 2014 Dec; 1843(12):2976-2988. PubMed ID: 25219551
[TBL] [Abstract][Full Text] [Related]
18. Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap.
Spaargaren M; Bischoff JR
Proc Natl Acad Sci U S A; 1994 Dec; 91(26):12609-13. PubMed ID: 7809086
[TBL] [Abstract][Full Text] [Related]
19. The RAL signaling network: Cancer and beyond.
Apken LH; Oeckinghaus A
Int Rev Cell Mol Biol; 2021; 361():21-105. PubMed ID: 34074494
[TBL] [Abstract][Full Text] [Related]
20. Ras caught in another affair: the exchange factors for Ral.
Wolthuis RM; Bos JL
Curr Opin Genet Dev; 1999 Feb; 9(1):112-7. PubMed ID: 10072355
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
