These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 35065073)

  • 1. Targeting Wnt/tenascin C-mediated cross talk between pancreatic cancer cells and stellate cells via activation of the metastasis suppressor NDRG1.
    Geleta B; Tout FS; Lim SC; Sahni S; Jansson PJ; Apte MV; Richardson DR; Kovačević Ž
    J Biol Chem; 2022 Mar; 298(3):101608. PubMed ID: 35065073
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma.
    Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z
    FASEB J; 2021 Feb; 35(2):e21347. PubMed ID: 33484481
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thiosemicarbazones reprogram pancreatic cancer bidirectional oncogenic signaling between cancer cells and stellate cells to suppress desmoplasia.
    Richardson DR; Azad MG; Afroz R; Richardson V; Dharmasivam M
    Future Med Chem; 2022 Jul; 14(13):1005-1017. PubMed ID: 35670251
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
    Kovacevic Z; Menezes SV; Sahni S; Kalinowski DS; Bae DH; Lane DJ; Richardson DR
    J Biol Chem; 2016 Jan; 291(3):1029-52. PubMed ID: 26534963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multi-modal mechanisms of the metastasis suppressor, NDRG1: Inhibition of WNT/β-catenin signaling by stabilization of protein kinase Cα.
    Gholam Azad M; Hussaini M; Russell TM; Richardson V; Kaya B; Dharmasivam M; Richardson DR
    J Biol Chem; 2024 Jul; 300(7):107417. PubMed ID: 38815861
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The metastasis suppressor, NDRG1, attenuates oncogenic TGF-β and NF-κB signaling to enhance membrane E-cadherin expression in pancreatic cancer cells.
    Menezes SV; Fouani L; Huang MLH; Geleta B; Maleki S; Richardson A; Richardson DR; Kovacevic Z
    Carcinogenesis; 2019 Jul; 40(6):805-818. PubMed ID: 30561520
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Iron chelator-induced up-regulation of Ndrg1 inhibits proliferation and EMT process by targeting Wnt/β-catenin pathway in colon cancer cells.
    Chen Z; Sun J; Li T; Liu Y; Gao S; Zhi X; Zheng M
    Biochem Biophys Res Commun; 2018 Nov; 506(1):114-121. PubMed ID: 30340826
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions.
    Jiang Z; Zhou C; Cheng L; Yan B; Chen K; Chen X; Zong L; Lei J; Duan W; Xu Q; Li X; Wang Z; Ma Q; Ma J
    J Exp Clin Cancer Res; 2018 Mar; 37(1):69. PubMed ID: 29587800
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).
    Chen Z; Zhang D; Yue F; Zheng M; Kovacevic Z; Richardson DR
    J Biol Chem; 2012 May; 287(21):17016-17028. PubMed ID: 22453918
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression.
    Froeling FE; Feig C; Chelala C; Dobson R; Mein CE; Tuveson DA; Clevers H; Hart IR; Kocher HM
    Gastroenterology; 2011 Oct; 141(4):1486-97, 1497.e1-14. PubMed ID: 21704588
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of β-catenin through mechanisms involving FRAT1 and PAK4.
    Jin R; Liu W; Menezes S; Yue F; Zheng M; Kovacevic Z; Richardson DR
    J Cell Sci; 2014 Jul; 127(Pt 14):3116-30. PubMed ID: 24829151
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways.
    Kovacevic Z; Chikhani S; Lui GY; Sivagurunathan S; Richardson DR
    Antioxid Redox Signal; 2013 Mar; 18(8):874-87. PubMed ID: 22462691
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition.
    Lee YC; Lin SC; Yu G; Zhu M; Song JH; Rivera K; Pappin DJ; Logothetis CJ; Panaretakis T; Wang G; Yu-Lee LY; Lin SH
    Oncogene; 2022 Feb; 41(6):757-769. PubMed ID: 34845375
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Imbalance of Wnt/Dkk negative feedback promotes persistent activation of pancreatic stellate cells in chronic pancreatitis.
    Hu Y; Wan R; Yu G; Shen J; Ni J; Yin G; Xing M; Chen C; Fan Y; Xiao W; Xu G; Wang X; Hu G
    PLoS One; 2014; 9(4):e95145. PubMed ID: 24747916
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
    Wangpu X; Lu J; Xi R; Yue F; Sahni S; Park KC; Menezes S; Huang ML; Zheng M; Kovacevic Z; Richardson DR
    Mol Pharmacol; 2016 May; 89(5):521-40. PubMed ID: 26895766
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pancreatic stellate cells exploit Wnt/β-catenin/TCF7-mediated glutamine metabolism to promote pancreatic cancer cells growth.
    Liu H; Zhang H; Liu X; Guo W; Liu Q; Chen L; Pang J; Liu X; Li R; Tong WM; Wu H; Dai M; Liang Z
    Cancer Lett; 2023 Feb; 555():216040. PubMed ID: 36565920
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PITX2 in pancreatic stellate cells promotes EMT in pancreatic cancer cells via the Wnt/β-catenin pathway.
    Wu D; Chen W; Yang Y; Qin Y; Zu G; Zhang Y; An Y; Sun D; Xu X; Chen X
    Acta Biochim Biophys Sin (Shanghai); 2023 Jun; 55(9):1393-1403. PubMed ID: 37337632
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel Thiosemicarbazones Inhibit Lysine-Rich Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) Coisolated (LYRIC) and the LYRIC-Induced Epithelial-Mesenchymal Transition via Upregulation of N-Myc Downstream-Regulated Gene 1 (NDRG1).
    Xi R; Pun IH; Menezes SV; Fouani L; Kalinowski DS; Huang ML; Zhang X; Richardson DR; Kovacevic Z
    Mol Pharmacol; 2017 May; 91(5):499-517. PubMed ID: 28275050
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The metastasis suppressor, NDRG1, inhibits "stemness" of colorectal cancer via down-regulation of nuclear β-catenin and CD44.
    Wangpu X; Yang X; Zhao J; Lu J; Guan S; Lu J; Kovacevic Z; Liu W; Mi L; Jin R; Sun J; Yue F; Ma J; Lu A; Richardson DR; Wang L; Zheng M
    Oncotarget; 2015 Oct; 6(32):33893-911. PubMed ID: 26418878
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Galectin-3 Mediates Tumor Cell-Stroma Interactions by Activating Pancreatic Stellate Cells to Produce Cytokines via Integrin Signaling.
    Zhao W; Ajani JA; Sushovan G; Ochi N; Hwang R; Hafley M; Johnson RL; Bresalier RS; Logsdon CD; Zhang Z; Song S
    Gastroenterology; 2018 Apr; 154(5):1524-1537.e6. PubMed ID: 29274868
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.