These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 35074483)

  • 1. Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
    Nielsen J; Brandt J; Boesen T; Hummelshøj T; Slaaby R; Schluckebier G; Nissen P
    J Mol Biol; 2022 Mar; 434(5):167458. PubMed ID: 35074483
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex.
    Uchikawa E; Choi E; Shang G; Yu H; Bai XC
    Elife; 2019 Aug; 8():. PubMed ID: 31436533
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
    Scapin G; Dandey VP; Zhang Z; Prosise W; Hruza A; Kelly T; Mayhood T; Strickland C; Potter CS; Carragher B
    Nature; 2018 Apr; 556(7699):122-125. PubMed ID: 29512653
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain.
    Gutmann T; Schäfer IB; Poojari C; Brankatschk B; Vattulainen I; Strauss M; Coskun Ü
    J Cell Biol; 2020 Jan; 219(1):. PubMed ID: 31727777
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor.
    Gutmann T; Kim KH; Grzybek M; Walz T; Coskun Ü
    J Cell Biol; 2018 May; 217(5):1643-1649. PubMed ID: 29453311
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The signalling conformation of the insulin receptor ectodomain.
    Weis F; Menting JG; Margetts MB; Chan SJ; Xu Y; Tennagels N; Wohlfart P; Langer T; Müller CW; Dreyer MK; Lawrence MC
    Nat Commun; 2018 Oct; 9(1):4420. PubMed ID: 30356040
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.
    Whitten AE; Smith BJ; Menting JG; Margetts MB; McKern NM; Lovrecz GO; Adams TE; Richards K; Bentley JD; Trewhella J; Ward CW; Lawrence MC
    J Mol Biol; 2009 Dec; 394(5):878-92. PubMed ID: 19835884
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Complementation analysis demonstrates that insulin cross-links both alpha subunits in a truncated insulin receptor dimer.
    Chan SJ; Nakagawa S; Steiner DF
    J Biol Chem; 2007 May; 282(18):13754-8. PubMed ID: 17339314
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis of the activation of type 1 insulin-like growth factor receptor.
    Li J; Choi E; Yu H; Bai XC
    Nat Commun; 2019 Oct; 10(1):4567. PubMed ID: 31594955
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
    Li J; Wu J; Hall C; Bai XC; Choi E
    Elife; 2022 Nov; 11():. PubMed ID: 36413010
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor alpha-chain C-terminal peptide and the site 1 insulin mimetic peptides.
    Menting JG; Ward CW; Margetts MB; Lawrence MC
    Biochemistry; 2009 Jun; 48(23):5492-500. PubMed ID: 19459609
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural insights into ligand-induced activation of the insulin receptor.
    Ward C; Lawrence M; Streltsov V; Garrett T; McKern N; Lou MZ; Lovrecz G; Adams T
    Acta Physiol (Oxf); 2008 Jan; 192(1):3-9. PubMed ID: 18171424
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Activation Mechanism of the Insulin Receptor: A Structural Perspective.
    Choi E; Bai XC
    Annu Rev Biochem; 2023 Jun; 92():247-272. PubMed ID: 37001136
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapid Non-Enzymatic Glycation of the Insulin Receptor under Hyperglycemic Conditions Inhibits Insulin Binding In Vitro: Implications for Insulin Resistance.
    Rhinesmith T; Turkette T; Root-Bernstein R
    Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29207492
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prediction of a novel internal rearrangement of the insulin receptor.
    Sit KC; van Lonkhuyzen D; Walsh T; Croll T
    J Biomol Struct Dyn; 2017 Mar; 35(4):857-867. PubMed ID: 27137342
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain.
    Croll TI; Smith BJ; Margetts MB; Whittaker J; Weiss MA; Ward CW; Lawrence MC
    Structure; 2016 Mar; 24(3):469-76. PubMed ID: 26853939
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure and dynamics of the insulin receptor: implications for receptor activation and drug discovery.
    Ye L; Maji S; Sanghera N; Gopalasingam P; Gorbunov E; Tarasov S; Epstein O; Klein-Seetharaman J
    Drug Discov Today; 2017 Jul; 22(7):1092-1102. PubMed ID: 28476537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The insulin and IGF1 receptor kinase domains are functional dimers in the activated state.
    Cabail MZ; Li S; Lemmon E; Bowen ME; Hubbard SR; Miller WT
    Nat Commun; 2015 Mar; 6():6406. PubMed ID: 25758790
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the insulin receptor by insulin-like growth factor 2.
    An W; Hall C; Li J; Hung A; Wu J; Park J; Wang L; Bai XC; Choi E
    Nat Commun; 2024 Mar; 15(1):2609. PubMed ID: 38521788
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
    Hexnerová R; Křížková K; Fábry M; Sieglová I; Kedrová K; Collinsová M; Ullrichová P; Srb P; Williams C; Crump MP; Tošner Z; Jiráček J; Veverka V; Žáková L
    J Biol Chem; 2016 Sep; 291(40):21234-21245. PubMed ID: 27510031
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.