BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 35075369)

  • 1.
    Hadizadeh F; Ghodsi R; Mirzaei S; Sahebkar A
    Comput Math Methods Med; 2022; 2022():4004068. PubMed ID: 35075369
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of potent microtubule-destabilizing agents targeting for colchicine site by virtual screening, biological evaluation, and molecular dynamics simulation.
    Zhang H; Luo QQ; Hu ML; Wang N; Qi HZ; Zhang HR; Ding L
    Eur J Pharm Sci; 2023 Jan; 180():106340. PubMed ID: 36435355
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of Essential 2D and 3D Chemical Features for Discovery of the Novel Tubulin Polymerization Inhibitors.
    Azimi F; Ghasemi JB; Saghaei L; Hassanzadeh F; Mahdavi M; Sadeghi-Aliabadi H; Scotti MT; Scotti L
    Curr Top Med Chem; 2019; 19(13):1092-1120. PubMed ID: 31109275
    [TBL] [Abstract][Full Text] [Related]  

  • 4. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
    Wang G; Peng Z; Peng S; Qiu J; Li Y; Lan Y
    Bioorg Med Chem Lett; 2018 Nov; 28(20):3350-3355. PubMed ID: 30197030
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes.
    Majcher U; Urbaniak A; Maj E; Moshari M; Delgado M; Wietrzyk J; Bartl F; Chambers TC; Tuszynski JA; Huczyński A
    Bioorg Chem; 2018 Dec; 81():553-566. PubMed ID: 30248507
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tubulin inhibitors: pharmacophore modeling, virtual screening and molecular docking.
    Niu MM; Qin JY; Tian CP; Yan XF; Dong FG; Cheng ZQ; Fida G; Yang M; Chen HY; Gu YQ
    Acta Pharmacol Sin; 2014 Jul; 35(7):967-79. PubMed ID: 24909516
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of novel tubulin inhibitors targeting taxanes site by virtual screening, molecular dynamic simulation, and biological evaluation.
    Zhang H; Mao J; Yang YL; Liu CT; Shen C; Zhang HR; Xie HZ; Ding L
    J Cell Biochem; 2021 Nov; 122(11):1609-1624. PubMed ID: 34237164
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 3D-QSAR-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Tubulin Inhibitors with Potential Anticancer Activity.
    Mirzaei S; Ghodsi R; Hadizadeh F; Sahebkar A
    Biomed Res Int; 2021; 2021():6480804. PubMed ID: 34485522
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel Aldimine-Type Schiff Bases of 4-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-1,2,4-triazole-3-thione/thiol: Docking Study, Synthesis, Biological Evaluation, and Anti-Tubulin Activity.
    Ameri A; Khodarahmi G; Hassanzadeh F; Forootanfar H; Hakimelahi GH
    Arch Pharm (Weinheim); 2016 Aug; 349(8):662-81. PubMed ID: 27320785
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
    Boichuk S; Galembikova A; Syuzov K; Dunaev P; Bikinieva F; Aukhadieva A; Zykova S; Igidov N; Gankova K; Novikova M; Kopnin P
    Molecules; 2021 Sep; 26(19):. PubMed ID: 34641324
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of microtubule stabilizers with novel scaffold structures based on virtual screening, biological evaluation, and molecular dynamics simulation.
    Mao J; Luo QQ; Zhang HR; Zheng XH; Shen C; Qi HZ; Hu ML; Zhang H
    Chem Biol Interact; 2022 Jan; 352():109784. PubMed ID: 34932952
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin.
    Sun K; Sun Z; Zhao F; Shan G; Meng Q
    Future Med Chem; 2021 May; 13(9):839-858. PubMed ID: 33821673
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations.
    Liu G; Jiao Y; Huang C; Chang P
    J Comput Aided Mol Des; 2019 Jul; 33(7):659-664. PubMed ID: 31165955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combined Molecular Docking, 3D-QSAR, and Pharmacophore Model: Design of Novel Tubulin Polymerization Inhibitors by Binding to Colchicine-binding Site.
    Li DD; Qin YJ; Zhang X; Yin Y; Zhu HL; Zhao LG
    Chem Biol Drug Des; 2015 Oct; 86(4):731-45. PubMed ID: 25711282
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and biological evaluation of novel 5,6,7-trimethoxy-N-aryl-2-styrylquinolin-4-amines as potential anticancer agents and tubulin polymerization inhibitors.
    Mirzaei S; Eisvand F; Hadizadeh F; Mosaffa F; Ghasemi A; Ghodsi R
    Bioorg Chem; 2020 May; 98():103711. PubMed ID: 32179282
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Consensus Virtual Screening Protocol Towards the Identification of Small Molecules Interacting with the Colchicine Binding Site of the Tubulin-microtubule System.
    López-López E; Cerda-García-Rojas CM; Medina-Franco JL
    Mol Inform; 2023 Jan; 42(1):e2200166. PubMed ID: 36175374
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
    Wang Y; Zhang H; Gigant B; Yu Y; Wu Y; Chen X; Lai Q; Yang Z; Chen Q; Yang J
    FEBS J; 2016 Jan; 283(1):102-11. PubMed ID: 26462166
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
    Cheng B; Zhu G; Meng L; Wu G; Chen Q; Ma S
    Eur J Med Chem; 2022 Jan; 228():113930. PubMed ID: 34794817
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
    Prota AE; Danel F; Bachmann F; Bargsten K; Buey RM; Pohlmann J; Reinelt S; Lane H; Steinmetz MO
    J Mol Biol; 2014 Apr; 426(8):1848-60. PubMed ID: 24530796
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-Based Pharmacophore Design and Virtual Screening for Novel Tubulin Inhibitors with Potential Anticancer Activity.
    Zhou Y; Di B; Niu MM
    Molecules; 2019 Sep; 24(17):. PubMed ID: 31480625
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.