BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 35078269)

  • 1. Mechanistic and therapeutic role of Drp1 in the pathogenesis of Alzheimer's disease.
    Bera A; Lavanya G; Reshmi R; Dev K; Kumar R
    Eur J Neurosci; 2022 Nov; 56(9):5516-5531. PubMed ID: 35078269
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
    Baek SH; Park SJ; Jeong JI; Kim SH; Han J; Kyung JW; Baik SH; Choi Y; Choi BY; Park JS; Bahn G; Shin JH; Jo DS; Lee JY; Jang CG; Arumugam TV; Kim J; Han JW; Koh JY; Cho DH; Jo DG
    J Neurosci; 2017 May; 37(20):5099-5110. PubMed ID: 28432138
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
    Kandimalla R; Manczak M; Fry D; Suneetha Y; Sesaki H; Reddy PH
    Hum Mol Genet; 2016 Nov; 25(22):4881-4897. PubMed ID: 28173111
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
    Manczak M; Reddy PH
    Hum Mol Genet; 2012 Jun; 21(11):2538-47. PubMed ID: 22367970
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial dysfunction, mitophagy, and role of dynamin-related protein 1 in Alzheimer's disease.
    Medala VK; Gollapelli B; Dewanjee S; Ogunmokun G; Kandimalla R; Vallamkondu J
    J Neurosci Res; 2021 Apr; 99(4):1120-1135. PubMed ID: 33465841
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer's Disease.
    Reddy PH; Oliver DM
    Cells; 2019 May; 8(5):. PubMed ID: 31121890
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting dynamin-related protein-1 as a potential therapeutic approach for mitochondrial dysfunction in Alzheimer's disease.
    Bhatti JS; Kaur S; Mishra J; Dibbanti H; Singh A; Reddy AP; Bhatti GK; Reddy PH
    Biochim Biophys Acta Mol Basis Dis; 2023 Oct; 1869(7):166798. PubMed ID: 37392948
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
    Manczak M; Kandimalla R; Fry D; Sesaki H; Reddy PH
    Hum Mol Genet; 2016 Dec; 25(23):5148-5166. PubMed ID: 27677309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A partial reduction of Drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic Tau mouse model of Alzheimer disease.
    Kandimalla R; Manczak M; Pradeepkiran JA; Morton H; Reddy PH
    Hum Mol Genet; 2022 Jun; 31(11):1788-1805. PubMed ID: 34919689
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Blockage of GSK3β-mediated Drp1 phosphorylation provides neuroprotection in neuronal and mouse models of Alzheimer's disease.
    Yan J; Liu XH; Han MZ; Wang YM; Sun XL; Yu N; Li T; Su B; Chen ZY
    Neurobiol Aging; 2015 Jan; 36(1):211-27. PubMed ID: 25192600
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dynamin-related protein 1: A critical protein in the pathogenesis of neural system dysfunctions and neurodegenerative diseases.
    Qi Z; Huang Z; Xie F; Chen L
    J Cell Physiol; 2019 Jul; 234(7):10032-10046. PubMed ID: 30515821
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
    Manczak M; Calkins MJ; Reddy PH
    Hum Mol Genet; 2011 Jul; 20(13):2495-509. PubMed ID: 21459773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The distinctive role of tau and amyloid beta in mitochondrial dysfunction through alteration in Mfn2 and Drp1 mRNA Levels: A comparative study in Drosophila melanogaster.
    Abtahi SL; Masoudi R; Haddadi M
    Gene; 2020 Sep; 754():144854. PubMed ID: 32525045
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased O-GlcNAcylation of Drp1 by amyloid-beta promotes mitochondrial fission and dysfunction in neuronal cells.
    Park SJ; Bae JE; Jo DS; Kim JB; Park NY; Fang J; Jung YK; Jo DG; Cho DH
    Mol Brain; 2021 Jan; 14(1):6. PubMed ID: 33422108
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent Advances in Molecular Pathways and Therapeutic Implications Targeting Mitochondrial Dysfunction for Alzheimer's Disease.
    Dhapola R; Sarma P; Medhi B; Prakash A; Reddy DH
    Mol Neurobiol; 2022 Jan; 59(1):535-555. PubMed ID: 34725778
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of proline-rich tyrosine kinase 2 (Pyk2) in the pathogenesis of Alzheimer's disease.
    Kumar R; Tiwari V; Dey S
    Eur J Neurosci; 2022 Nov; 56(9):5442-5452. PubMed ID: 34905657
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synaptic Mitochondria: An Early Target of Amyloid-β and Tau in Alzheimer's Disease.
    Torres AK; Jara C; Park-Kang HS; Polanco CM; Tapia D; Alarcón F; de la Peña A; Llanquinao J; Vargas-Mardones G; Indo JA; Inestrosa NC; Tapia-Rojas C
    J Alzheimers Dis; 2021; 84(4):1391-1414. PubMed ID: 34719499
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse.
    Morton H; Kshirsagar S; Orlov E; Bunquin LE; Sawant N; Boleng L; George M; Basu T; Ramasubramanian B; Pradeepkiran JA; Kumar S; Vijayan M; Reddy AP; Reddy PH
    Free Radic Biol Med; 2021 Aug; 172():652-667. PubMed ID: 34246776
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of Cdk5-mediated Drp1 phosphorylation in Aβ
    Guo MY; Shang L; Hu YY; Jiang LP; Wan YY; Zhou QQ; Zhang K; Liao HF; Yi JL; Han XJ
    J Cell Biochem; 2018 Jun; 119(6):4815-4825. PubMed ID: 29345339
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
    Manczak M; Reddy PH
    Hum Mol Genet; 2012 Dec; 21(23):5131-46. PubMed ID: 22926141
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.