197 related articles for article (PubMed ID: 35082301)
1. Differential roles for DNAJ isoforms in HTT-polyQ and FUS aggregation modulation revealed by chaperone screens.
Rozales K; Younis A; Saida N; Meller A; Goldman H; Kellerman L; Heinrich R; Berlin S; Shalgi R
Nat Commun; 2022 Jan; 13(1):516. PubMed ID: 35082301
[TBL] [Abstract][Full Text] [Related]
2. PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
Yue HW; Hong JY; Zhang SX; Jiang LL; Hu HY
Sci Rep; 2021 Apr; 11(1):7815. PubMed ID: 33837238
[TBL] [Abstract][Full Text] [Related]
3. Co-chaperones DNAJA1 and DNAJB6 are critical for regulation of polyglutamine aggregation.
Rodríguez-González C; Lin S; Arkan S; Hansen C
Sci Rep; 2020 May; 10(1):8130. PubMed ID: 32424160
[TBL] [Abstract][Full Text] [Related]
4. Astrocytic expression of the chaperone DNAJB6 results in non-cell autonomous protection in Huntington's disease.
Bason M; Meister-Broekema M; Alberts N; Dijkers P; Bergink S; Sibon OCM; Kampinga HH
Neurobiol Dis; 2019 Apr; 124():108-117. PubMed ID: 30408590
[TBL] [Abstract][Full Text] [Related]
5. Proteostasis of Huntingtin in Health and Disease.
Koyuncu S; Fatima A; Gutierrez-Garcia R; Vilchez D
Int J Mol Sci; 2017 Jul; 18(7):. PubMed ID: 28753941
[TBL] [Abstract][Full Text] [Related]
6. Aptamer Reduces Aggregation of Mutant Huntingtin and Rescues Proteostasis Network in Non-Neuronal and Neuronal Cells.
Jain S; Roy I
ACS Chem Neurosci; 2023 Jun; 14(12):2385-2395. PubMed ID: 37294284
[TBL] [Abstract][Full Text] [Related]
7. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.
Koyuncu S; Saez I; Lee HJ; Gutierrez-Garcia R; Pokrzywa W; Fatima A; Hoppe T; Vilchez D
Nat Commun; 2018 Jul; 9(1):2886. PubMed ID: 30038412
[TBL] [Abstract][Full Text] [Related]
8. Suppression of protein aggregation by chaperone modification of high molecular weight complexes.
Labbadia J; Novoselov SS; Bett JS; Weiss A; Paganetti P; Bates GP; Cheetham ME
Brain; 2012 Apr; 135(Pt 4):1180-96. PubMed ID: 22396390
[TBL] [Abstract][Full Text] [Related]
9. Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex.
Scior A; Buntru A; Arnsburg K; Ast A; Iburg M; Juenemann K; Pigazzini ML; Mlody B; Puchkov D; Priller J; Wanker EE; Prigione A; Kirstein J
EMBO J; 2018 Jan; 37(2):282-299. PubMed ID: 29212816
[TBL] [Abstract][Full Text] [Related]
10. Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins.
Park SK; Arslan F; Kanneganti V; Barmada SJ; Purushothaman P; Verma SC; Liebman SW
Prion; 2018 Jan; 12(1):16-22. PubMed ID: 29308690
[TBL] [Abstract][Full Text] [Related]
11. Identification of a HTT-specific binding motif in DNAJB1 essential for suppression and disaggregation of HTT.
Ayala Mariscal SM; Pigazzini ML; Richter Y; Özel M; Grothaus IL; Protze J; Ziege K; Kulke M; ElBediwi M; Vermaas JV; Colombi Ciacchi L; Köppen S; Liu F; Kirstein J
Nat Commun; 2022 Aug; 13(1):4692. PubMed ID: 35948542
[TBL] [Abstract][Full Text] [Related]
12. Herp Promotes Degradation of Mutant Huntingtin: Involvement of the Proteasome and Molecular Chaperones.
Luo H; Cao L; Liang X; Du A; Peng T; Li H
Mol Neurobiol; 2018 Oct; 55(10):7652-7668. PubMed ID: 29430620
[TBL] [Abstract][Full Text] [Related]
13. Exploding the Repeat Length Paradigm while Exploring Amyloid Toxicity in Huntington's Disease.
Wetzel R
Acc Chem Res; 2020 Oct; 53(10):2347-2357. PubMed ID: 32975927
[TBL] [Abstract][Full Text] [Related]
14. Targeting DNA topoisomerases or checkpoint kinases results in an overload of chaperone systems, triggering aggregation of a metastable subproteome.
Huiting W; Dekker SL; van der Lienden JCJ; Mergener R; Musskopf MK; Furtado GV; Gerrits E; Coit D; Oghbaie M; Di Stefano LH; Schepers H; van Waarde-Verhagen MAWH; Couzijn S; Barazzuol L; LaCava J; Kampinga HH; Bergink S
Elife; 2022 Feb; 11():. PubMed ID: 35200138
[TBL] [Abstract][Full Text] [Related]
15. Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors.
Banerjee M; Datta M; Bhattacharyya NP
Int J Biochem Cell Biol; 2017 Jan; 82():1-9. PubMed ID: 27840155
[TBL] [Abstract][Full Text] [Related]
16. Aggregation landscapes of Huntingtin exon 1 protein fragments and the critical repeat length for the onset of Huntington's disease.
Chen M; Wolynes PG
Proc Natl Acad Sci U S A; 2017 Apr; 114(17):4406-4411. PubMed ID: 28400517
[TBL] [Abstract][Full Text] [Related]
17. The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.
Gillis J; Schipper-Krom S; Juenemann K; Gruber A; Coolen S; van den Nieuwendijk R; van Veen H; Overkleeft H; Goedhart J; Kampinga HH; Reits EA
J Biol Chem; 2013 Jun; 288(24):17225-37. PubMed ID: 23612975
[TBL] [Abstract][Full Text] [Related]
18. Effects of flanking sequences and cellular context on subcellular behavior and pathology of mutant HTT.
Chongtham A; Bornemann DJ; Barbaro BA; Lukacsovich T; Agrawal N; Syed A; Worthge S; Purcell J; Burke J; Chin TM; Marsh JL
Hum Mol Genet; 2020 Mar; 29(4):674-688. PubMed ID: 31943010
[TBL] [Abstract][Full Text] [Related]
19. Measurement of Chaperone-Mediated Effects on Polyglutamine Protein Aggregation by the Filter Trap Assay.
van Waarde-Verhagen MAWH; Kampinga HH
Methods Mol Biol; 2018; 1709():59-74. PubMed ID: 29177651
[TBL] [Abstract][Full Text] [Related]
20. DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios.
Månsson C; Kakkar V; Monsellier E; Sourigues Y; Härmark J; Kampinga HH; Melki R; Emanuelsson C
Cell Stress Chaperones; 2014 Mar; 19(2):227-39. PubMed ID: 23904097
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]