BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 35086846)

  • 21. CPI-613 rewires lipid metabolism to enhance pancreatic cancer apoptosis via the AMPK-ACC signaling.
    Gao L; Xu Z; Huang Z; Tang Y; Yang D; Huang J; He L; Liu M; Chen Z; Teng Y
    J Exp Clin Cancer Res; 2020 Apr; 39(1):73. PubMed ID: 32345326
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Evaluation of metabolism and disposition of GDC-0152 in rats using 14C labeling strategy at two different positions: a novel formation of hippuric acid from 4-phenyl-5-amino-1,2,3-thiadiazole.
    Yue Q; Mulder T; Rudewicz PJ; Solon E; Budha N; Ware JA; Lyssikatos J; Hop CE; Wong H; Khojasteh SC
    Drug Metab Dispos; 2013 Feb; 41(2):508-17. PubMed ID: 23223496
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Metabolism and elimination of 14C-donepezil in healthy volunteers: a single-dose study.
    Tiseo PJ; Perdomo CA; Friedhoff LT
    Br J Clin Pharmacol; 1998 Nov; 46 Suppl 1(Suppl 1):19-24. PubMed ID: 9839761
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Metabolism and pharmacokinetics of 3-n-butylphthalide (NBP) in humans: the role of cytochrome P450s and alcohol dehydrogenase in biotransformation.
    Diao X; Deng P; Xie C; Li X; Zhong D; Zhang Y; Chen X
    Drug Metab Dispos; 2013 Feb; 41(2):430-44. PubMed ID: 23169608
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans.
    Dean BJ; Chang S; Silva Elipe MV; Xia YQ; Braun M; Soli E; Zhao Y; Franklin RB; Karanam B
    Drug Metab Dispos; 2007 Feb; 35(2):283-92. PubMed ID: 17132765
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Metabolites characterization of a novel DPP-4 inhibitor, imigliptin in humans and rats using ultra-high performance liquid chromatography coupled with synapt high-resolution mass spectrometry.
    Liu Y; Yao X; Song L; Liu H; Zhao Q; Jiang J; Ni G; Shi C; Ma X; Zhou H; Liu D; Hu P
    J Pharm Biomed Anal; 2018 Aug; 157():189-200. PubMed ID: 29803910
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys.
    Tan EY; Hartmann G; Chen Q; Pereira A; Bradley S; Doss G; Zhang AS; Ho JZ; Braun MP; Dean DC; Tang W; Kumar S
    Drug Metab Dispos; 2010 Mar; 38(3):459-73. PubMed ID: 20016052
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Excretion, metabolism, and pharmacokinetics of CP-945,598, a selective cannabinoid receptor antagonist, in rats, mice, and dogs.
    Miao Z; Scott DO; Griffith DA; Day R; Prakash C
    Drug Metab Dispos; 2011 Dec; 39(12):2191-208. PubMed ID: 21875952
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Species-dependent metabolism of a novel selective α7 neuronal acetylcholine receptor agonist ABT-107.
    Liu H; Deng X; Liu J; Liu N; Stuart P; Xu H; Guan Z; Marsh KC; De Morais SM
    Xenobiotica; 2013 Sep; 43(9):803-16. PubMed ID: 23327533
    [TBL] [Abstract][Full Text] [Related]  

  • 30. In vitro drug metabolism of green tea catechins in human, monkey, dog, rat and mouse hepatocytes.
    Chen WW; Qin GY; Zhang T; Feng WY
    Drug Metab Lett; 2012 Jun; 6(2):73-93. PubMed ID: 22594564
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Utility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and man.
    Bayliss MK; Bell JA; Jenner WN; Park GR; Wilson K
    Xenobiotica; 1999 Mar; 29(3):253-68. PubMed ID: 10219966
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Metabolism and Mass Balance of the Novel Nonsteroidal Androgen Receptor Inhibitor Darolutamide in Humans.
    Taavitsainen P; Prien O; Kähkönen M; Niehues M; Korjamo T; Denner K; Nykänen P; Vuorela A; Jungmann NA; von Bühler CJ; Koskinen M; Zurth C; Gieschen H
    Drug Metab Dispos; 2021 Jun; 49(6):420-433. PubMed ID: 33785516
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Metabolism and Disposition of Hepatitis C Polymerase Inhibitor Dasabuvir in Humans.
    Shen J; Serby M; Reed A; Lee AJ; Menon R; Zhang X; Marsh K; Wan X; Kavetskaia O; Fischer V
    Drug Metab Dispos; 2016 Aug; 44(8):1139-47. PubMed ID: 27179126
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite.
    Glaenzel U; Jin Y; Hansen R; Schroer K; Rahmanzadeh G; Pfaar U; Jaap van Lier J; Borell H; Meissner A; Camenisch G; Zhao S
    Drug Metab Dispos; 2020 Oct; 48(10):873-885. PubMed ID: 32665418
    [TBL] [Abstract][Full Text] [Related]  

  • 35. In vitro and in vivo metabolism of a gamma-secretase inhibitor BMS-299897 and generation of active metabolites in milligram quantities with a microbial bioreactor.
    Zhang D; Hanson R; Roongta V; Dischino DD; Gao Q; Sloan CP; Polson C; Keavy D; Zheng M; Mitroka J; Yeola S
    Curr Drug Metab; 2006 Dec; 7(8):883-96. PubMed ID: 17168689
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Metabolism of [2-14C]p-hydroxyphenyl acetic acid in rat, monkey and human hepatocytes and in bile-duct cannulated rats.
    Zhou L; Liu-Kreyche P; Iyer RA
    Xenobiotica; 2011 Apr; 41(4):312-9. PubMed ID: 21143006
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase.
    Soreze Y; Boutron A; Habarou F; Barnerias C; Nonnenmacher L; Delpech H; Mamoune A; Chrétien D; Hubert L; Bole-Feysot C; Nitschke P; Correia I; Sardet C; Boddaert N; Hamel Y; Delahodde A; Ottolenghi C; de Lonlay P
    Orphanet J Rare Dis; 2013 Dec; 8():192. PubMed ID: 24341803
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification of metabolites of MDR-1339, an inhibitor of β-amyloid protein aggregation, and kinetic characterization of the major metabolites in rats.
    Son JH; Jeong YS; Lee JH; Kim MS; Lee KR; Shim CK; Kim YH; Chung SJ
    J Pharm Biomed Anal; 2018 Mar; 151():61-70. PubMed ID: 29306735
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The disulfide compound α-lipoic acid and its derivatives: A novel class of anticancer agents targeting mitochondria.
    Dörsam B; Fahrer J
    Cancer Lett; 2016 Feb; 371(1):12-9. PubMed ID: 26604131
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652.
    Rioux N; Mitchell LH; Tiller P; Plant K; Shaw J; Frost K; Ribich S; Moyer MP; Copeland RA; Chesworth R; Waters NJ
    Drug Metab Dispos; 2015 Jul; 43(7):936-43. PubMed ID: 25887455
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.