These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 35086847)

  • 21. Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.
    Fagerholm U
    J Pharm Pharmacol; 2007 Jun; 59(6):803-28. PubMed ID: 17637173
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Prediction of in vivo disposition from in vitro systems: clearance of phenytoin and tolbutamide using rat hepatic microsomal and hepatocyte data.
    Ashforth EI; Carlile DJ; Chenery R; Houston JB
    J Pharmacol Exp Ther; 1995 Aug; 274(2):761-6. PubMed ID: 7636740
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Comparison of the use of liver models for predicting drug clearance using in vitro kinetic data from hepatic microsomes and isolated hepatocytes.
    Ito K; Houston JB
    Pharm Res; 2004 May; 21(5):785-92. PubMed ID: 15180335
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A unified model for predicting human hepatic, metabolic clearance from in vitro intrinsic clearance data in hepatocytes and microsomes.
    Riley RJ; McGinnity DF; Austin RP
    Drug Metab Dispos; 2005 Sep; 33(9):1304-11. PubMed ID: 15932954
    [TBL] [Abstract][Full Text] [Related]  

  • 25. In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical Species.
    Tess DA; Ryu S; Di L
    Pharm Res; 2022 Jul; 39(7):1615-1632. PubMed ID: 35257289
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Evaluation of hepatic clearance prediction using in vitro data: emphasis on fraction unbound in plasma and drug ionisation using a database of 107 drugs.
    Hallifax D; Houston JB
    J Pharm Sci; 2012 Aug; 101(8):2645-52. PubMed ID: 22700322
    [TBL] [Abstract][Full Text] [Related]  

  • 27. New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data.
    Riede J; Poller B; Umehara K; Huwyler J; Camenisch G
    Eur J Pharm Sci; 2016 Apr; 86():96-102. PubMed ID: 26948853
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Quantitative prediction of glucuronidation in humans using the in vitro- in vivo extrapolation approach.
    Wu B; Dong D; Hu M; Zhang S
    Curr Top Med Chem; 2013; 13(11):1343-52. PubMed ID: 23675940
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Successful and Unsuccessful Prediction of Human Hepatic Clearance for Lead Optimization.
    Sodhi JK; Benet LZ
    J Med Chem; 2021 Apr; 64(7):3546-3559. PubMed ID: 33765384
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Impact of Plasma Protein Binding in Drug Clearance Prediction: A Data Base Analysis of Published Studies and Implications for In Vitro-In Vivo Extrapolation.
    Francis LJ; Houston JB; Hallifax D
    Drug Metab Dispos; 2021 Mar; 49(3):188-201. PubMed ID: 33355201
    [TBL] [Abstract][Full Text] [Related]  

  • 31. PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: comparative assessement of prediction methods of human clearance.
    Ring BJ; Chien JY; Adkison KK; Jones HM; Rowland M; Jones RD; Yates JW; Ku MS; Gibson CR; He H; Vuppugalla R; Marathe P; Fischer V; Dutta S; Sinha VK; Björnsson T; Lavé T; Poulin P
    J Pharm Sci; 2011 Oct; 100(10):4090-110. PubMed ID: 21541938
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Prediction of hepatic clearance in human from in vitro data for successful drug development.
    Chiba M; Ishii Y; Sugiyama Y
    AAPS J; 2009 Jun; 11(2):262-76. PubMed ID: 19408130
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Exploring the Boundaries for In Vitro-In Vivo Extrapolation: Use of Isolated Rat Hepatocytes in Co-culture and Impact of Albumin Binding Properties in the Prediction of Clearance of Various Drug Types.
    Francis L; Ogungbenro K; De Bruyn T; Houston JB; Hallifax D
    Drug Metab Dispos; 2023 Nov; 51(11):1463-1473. PubMed ID: 37580106
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Prediction of human drug clearance by multiple metabolic pathways: integration of hepatic and intestinal microsomal and cytosolic data.
    Cubitt HE; Houston JB; Galetin A
    Drug Metab Dispos; 2011 May; 39(5):864-73. PubMed ID: 21303923
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Use of Segregated Hepatocyte Scaling Factors and Cross-Species Relationships to Resolve Clearance Dependence in the Prediction of Human Hepatic Clearance.
    Hallifax D; Houston JB
    Drug Metab Dispos; 2019 Mar; 47(3):320-327. PubMed ID: 30610004
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Investigating the Theoretical Basis for In Vitro-In Vivo Extrapolation (IVIVE) in Predicting Drug Metabolic Clearance and Proposing Future Experimental Pathways.
    Benet LZ; Sodhi JK
    AAPS J; 2020 Sep; 22(5):120. PubMed ID: 32914238
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Prediction of human metabolic clearance from in vitro systems: retrospective analysis and prospective view.
    Hallifax D; Foster JA; Houston JB
    Pharm Res; 2010 Oct; 27(10):2150-61. PubMed ID: 20661765
    [TBL] [Abstract][Full Text] [Related]  

  • 38. In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance of Human and Preclinical Species with Liver Microsomes and Hepatocytes.
    Tess D; Chang GC; Keefer C; Carlo A; Jones R; Di L
    AAPS J; 2023 Apr; 25(3):40. PubMed ID: 37052732
    [TBL] [Abstract][Full Text] [Related]  

  • 39. In vitro-in vivo extrapolation of CYP2C8-catalyzed paclitaxel 6α-hydroxylation: effects of albumin on in vitro kinetic parameters and assessment of interindividual variability in predicted clearance.
    Wattanachai N; Polasek TM; Heath TM; Uchaipichat V; Tassaneeyakul W; Tassaneeyakul W; Miners JO
    Eur J Clin Pharmacol; 2011 Aug; 67(8):815-24. PubMed ID: 21305272
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effect of Human Plasma on Hepatic Uptake of Organic Anion-Transporting Polypeptide 1B Substrates: Studies Using Transfected Cells and Primary Human Hepatocytes.
    Bi YA; Ryu S; Tess DA; Rodrigues AD; Varma MVS
    Drug Metab Dispos; 2021 Jan; 49(1):72-83. PubMed ID: 33139461
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.