BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 35086928)

  • 1. Deletion of SUMO1 attenuates behavioral and anatomical deficits by regulating autophagic activities in Huntington disease.
    Ramírez-Jarquín UN; Sharma M; Zhou W; Shahani N; Subramaniam S
    Proc Natl Acad Sci U S A; 2022 Feb; 119(5):. PubMed ID: 35086928
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pramipexole reduces soluble mutant huntingtin and protects striatal neurons through dopamine D3 receptors in a genetic model of Huntington's disease.
    Luis-Ravelo D; Estévez-Silva H; Barroso-Chinea P; Afonso-Oramas D; Salas-Hernández J; Rodríguez-Núñez J; Acevedo-Arozena A; Marcellino D; González-Hernández T
    Exp Neurol; 2018 Jan; 299(Pt A):137-147. PubMed ID: 29056363
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
    Wang N; Gray M; Lu XH; Cantle JP; Holley SM; Greiner E; Gu X; Shirasaki D; Cepeda C; Li Y; Dong H; Levine MS; Yang XW
    Nat Med; 2014 May; 20(5):536-41. PubMed ID: 24784230
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice.
    Vodicka P; Chase K; Iuliano M; Valentine DT; Sapp E; Lu B; Kegel-Gleason KB; Sena-Esteves M; Aronin N; DiFiglia M
    J Huntingtons Dis; 2016 Jun; 5(2):163-74. PubMed ID: 27314618
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.
    Bailus BJ; Scheeler SM; Simons J; Sanchez MA; Tshilenge KT; Creus-Muncunill J; Naphade S; Lopez-Ramirez A; Zhang N; Lakshika Madushani K; Moroz S; Loureiro A; Schreiber KH; Hausch F; Kennedy BK; Ehrlich ME; Ellerby LM
    Autophagy; 2021 Dec; 17(12):4119-4140. PubMed ID: 34024231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease.
    Sharma M; Rajendrarao S; Shahani N; Ramírez-Jarquín UN; Subramaniam S
    Proc Natl Acad Sci U S A; 2020 Jul; 117(27):15989-15999. PubMed ID: 32581130
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of GSK-3 ameliorates the pathogenesis of Huntington's disease.
    Rippin I; Bonder K; Joseph S; Sarsor A; Vaks L; Eldar-Finkelman H
    Neurobiol Dis; 2021 Jul; 154():105336. PubMed ID: 33753290
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.
    Jiang M; Zhang X; Liu H; LeBron J; Alexandris A; Peng Q; Gu H; Yang F; Li Y; Wang R; Hou Z; Arbez N; Ren Q; Dong JL; Whela E; Wang R; Ratovitski T; Troncoso JC; Mori S; Ross CA; Lim J; Duan W
    Hum Mol Genet; 2020 May; 29(8):1340-1352. PubMed ID: 32242231
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy.
    Carbo M; Brandi V; Pascarella G; Staid DS; Colotti G; Polticelli F; Ilari A; Morea V
    Int J Mol Med; 2019 Dec; 44(6):2223-2233. PubMed ID: 31638189
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease.
    Ehrnhoefer DE; Martin DDO; Schmidt ME; Qiu X; Ladha S; Caron NS; Skotte NH; Nguyen YTN; Vaid K; Southwell AL; Engemann S; Franciosi S; Hayden MR
    Acta Neuropathol Commun; 2018 Mar; 6(1):16. PubMed ID: 29510748
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes.
    Hong Y; Zhao T; Li XJ; Li S
    J Neurosci; 2017 Sep; 37(39):9550-9563. PubMed ID: 28893927
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HIPK3 modulates autophagy and HTT protein levels in neuronal and mouse models of Huntington disease.
    Fu Y; Sun X; Lu B
    Autophagy; 2018; 14(1):169-170. PubMed ID: 29130397
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.
    Swarnkar S; Chen Y; Pryor WM; Shahani N; Page DT; Subramaniam S
    Neurobiol Dis; 2015 Oct; 82():66-77. PubMed ID: 26048156
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Atg4b-dependent autophagic flux alleviates Huntington's disease progression.
    Proenca CC; Stoehr N; Bernhard M; Seger S; Genoud C; Roscic A; Paganetti P; Liu S; Murphy LO; Kuhn R; Bouwmeester T; Galimberti I
    PLoS One; 2013; 8(7):e68357. PubMed ID: 23861892
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LAMP2A-mediated autophagy involved in Huntington's disease progression.
    Choi SH; Cho K
    Biochem Biophys Res Commun; 2021 Jan; 534():561-567. PubMed ID: 33239172
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutant huntingtin expression in microglia is neither required nor sufficient to cause the Huntington's disease-like phenotype in BACHD mice.
    Petkau TL; Hill A; Connolly C; Lu G; Wagner P; Kosior N; Blanco J; Leavitt BR
    Hum Mol Genet; 2019 May; 28(10):1661-1670. PubMed ID: 30624705
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Striatal Induction and Spread of the Huntington's Disease Protein: A Novel Rhes Route.
    Subramaniam S
    J Huntingtons Dis; 2022; 11(3):281-290. PubMed ID: 35871361
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cerebrospinal fluid mutant huntingtin is a biomarker for huntingtin lowering in the striatum of Huntington disease mice.
    Caron NS; Banos R; Aly AE; Xie Y; Ko S; Potluri N; Anderson C; Black HF; Anderson LM; Gordon B; Southwell AL; Hayden MR
    Neurobiol Dis; 2022 May; 166():105652. PubMed ID: 35143966
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cell-Autonomous and Non-cell-Autonomous Pathogenic Mechanisms in Huntington's Disease: Insights from In Vitro and In Vivo Models.
    Creus-Muncunill J; Ehrlich ME
    Neurotherapeutics; 2019 Oct; 16(4):957-978. PubMed ID: 31529216
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice.
    Vodicka P; Chase K; Iuliano M; Tousley A; Valentine DT; Sapp E; Kegel-Gleason KB; Sena-Esteves M; Aronin N; DiFiglia M
    J Huntingtons Dis; 2016 Oct; 5(3):249-260. PubMed ID: 27689619
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.