BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 35092472)

  • 1. Astragaloside IV suppresses migration and invasion of TGF-β
    Li L; Wang Q; He Y; Sun L; Yang Y; Pang X
    Naunyn Schmiedebergs Arch Pharmacol; 2022 Apr; 395(4):397-405. PubMed ID: 35092472
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Astragaloside IV inhibits hepatocellular carcinoma by continually suppressing the development of fibrosis and regulating pSmad3C/3L and Nrf2/HO-1 pathways.
    Zhang C; Li L; Hou S; Shi Z; Xu W; Wang Q; He Y; Gong Y; Fang Z; Yang Y
    J Ethnopharmacol; 2021 Oct; 279():114350. PubMed ID: 34157326
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amelioratory effects of astragaloside IV on hepatocarcinogenesis via Nrf2-mediated pSmad3C/3L transformation.
    Fang Gong Y; Hou S; Xu JC; Chen Y; Zhu LL; Xu YY; Chen YQ; Li MM; Li LL; Yang JJ; Yang Y
    Phytomedicine; 2023 Aug; 117():154903. PubMed ID: 37301185
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nrf2 knockout attenuates the astragaloside IV therapeutic effect on kidney fibrosis from liver cancer by regulating pSmad3C/3L pathways.
    Wang Q; Xu J; Li M; Chen Y; Xu Y; Li L; Gong Y; Yang Y
    Naunyn Schmiedebergs Arch Pharmacol; 2024 Mar; 397(3):1687-1700. PubMed ID: 37712971
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21(WAF1) pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells.
    Li Q; Liu G; Yuan H; Wang J; Guo Y; Chen T; Zhai R; Shao D; Ni W; Tai G
    Oncotarget; 2015 Feb; 6(6):4253-65. PubMed ID: 25714018
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocellular carcinoma progression via miR-145/miR-21 mediated Smad3 phosphorylation.
    Wu C; Chen W; Fang M; Boye A; Tao X; Xu Y; Hou S; Yang Y
    J Ethnopharmacol; 2019 Mar; 231():98-112. PubMed ID: 30412748
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B.
    Murata M; Matsuzaki K; Yoshida K; Sekimoto G; Tahashi Y; Mori S; Uemura Y; Sakaida N; Fujisawa J; Seki T; Kobayashi K; Yokote K; Koike K; Okazaki K
    Hepatology; 2009 Apr; 49(4):1203-17. PubMed ID: 19263472
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heme oxygenase-1/carbon monoxide axis suppresses transforming growth factor-β1-induced growth inhibition by increasing ERK1/2-mediated phosphorylation of Smad3 at Thr-179 in human hepatocellular carcinoma cell lines.
    Park SJ; Lee SK; Lim CR; Park HW; Liu F; Kim SJ; Kim BC
    Biochem Biophys Res Commun; 2018 Apr; 498(3):609-615. PubMed ID: 29524413
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling.
    Liu R; Tang C; Shen A; Luo H; Wei X; Zheng D; Sun C; Li Z; Zhu D; Li T; Wu Z
    Oncotarget; 2016 Dec; 7(51):85079-85096. PubMed ID: 27835881
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chalcone flavokawain A attenuates TGF-β1-induced fibrotic pathology via inhibition of ROS/Smad3 signaling pathways and induction of Nrf2/ARE-mediated antioxidant genes in vascular smooth muscle cells.
    Hseu YC; Yang TY; Li ML; Rajendran P; Mathew DC; Tsai CH; Lin RW; Lee CC; Yang HL
    J Cell Mol Med; 2019 Feb; 23(2):775-788. PubMed ID: 30549180
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma.
    Matsuzaki K; Murata M; Yoshida K; Sekimoto G; Uemura Y; Sakaida N; Kaibori M; Kamiyama Y; Nishizawa M; Fujisawa J; Okazaki K; Seki T
    Hepatology; 2007 Jul; 46(1):48-57. PubMed ID: 17596875
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of Nrf2/AREs-mediated antioxidant signalling, and suppression of profibrotic TGF-β1/Smad3 pathway: a promising therapeutic strategy for hepatic fibrosis - A review.
    Gong Y; Yang Y
    Life Sci; 2020 Sep; 256():117909. PubMed ID: 32512009
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Compound Astragalus and Salvia miltiorrhiza extracts modulate MAPK-regulated TGF-β/Smad signaling in hepatocellular carcinoma by multi-target mechanism.
    Boye A; Wu C; Jiang Y; Wang J; Wu J; Yang X; Yang Y
    J Ethnopharmacol; 2015 Jul; 169():219-28. PubMed ID: 25934513
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hesperidin protects against chemically induced hepatocarcinogenesis via modulation of Nrf2/ARE/HO-1, PPARγ and TGF-β1/Smad3 signaling, and amelioration of oxidative stress and inflammation.
    Mahmoud AM; Mohammed HM; Khadrawy SM; Galaly SR
    Chem Biol Interact; 2017 Nov; 277():146-158. PubMed ID: 28935427
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Smad3 phosphoisoform-mediated signaling during sporadic human colorectal carcinogenesis.
    Matsuzaki K
    Histol Histopathol; 2006 Jun; 21(6):645-62. PubMed ID: 16528675
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis.
    Kawamata S; Matsuzaki K; Murata M; Seki T; Matsuoka K; Iwao Y; Hibi T; Okazaki K
    Inflamm Bowel Dis; 2011 Mar; 17(3):683-95. PubMed ID: 20602465
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Curcumin Attenuates on Carbon Tetrachloride-Induced Acute Liver Injury in Mice via Modulation of the Nrf2/HO-1 and TGF-β1/Smad3 Pathway.
    Peng X; Dai C; Liu Q; Li J; Qiu J
    Molecules; 2018 Jan; 23(1):. PubMed ID: 29351226
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma.
    Nagata H; Hatano E; Tada M; Murata M; Kitamura K; Asechi H; Narita M; Yanagida A; Tamaki N; Yagi S; Ikai I; Matsuzaki K; Uemoto S
    Hepatology; 2009 Jun; 49(6):1944-53. PubMed ID: 19418558
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Smad3 and its phosphoisoforms are prognostic predictors of hepatocellular carcinoma after curative hepatectomy.
    Kim SH; Ahn S; Park CK
    Hepatobiliary Pancreat Dis Int; 2012 Feb; 11(1):51-9. PubMed ID: 22251470
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Asiaticoside inhibits TGF-β1-induced mesothelial-mesenchymal transition and oxidative stress via the Nrf2/HO-1 signaling pathway in the human peritoneal mesothelial cell line HMrSV5.
    Zhao J; Shi J; Shan Y; Yu M; Zhu X; Zhu Y; Liu L; Sheng M
    Cell Mol Biol Lett; 2020; 25():33. PubMed ID: 32514269
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.