BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 35101776)

  • 21. New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1.
    Dyrkheeva NS; Filimonov AS; Luzina OA; Orlova KA; Chernyshova IA; Kornienko TE; Malakhova AA; Medvedev SP; Zakharenko AL; Ilina ES; Anarbaev RO; Naumenko KN; Klabenkova KV; Burakova EA; Stetsenko DA; Zakian SM; Salakhutdinov NF; Lavrik OI
    Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768766
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Depletion of tyrosyl DNA phosphodiesterase 2 activity enhances etoposide-mediated double-strand break formation and cell killing.
    Kont YS; Dutta A; Mallisetty A; Mathew J; Minas T; Kraus C; Dhopeshwarkar P; Kallakury B; Mitra S; Üren A; Adhikari S
    DNA Repair (Amst); 2016 Jul; 43():38-47. PubMed ID: 27235629
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mammalian Tyrosyl-DNA Phosphodiesterases in the Context of Mitochondrial DNA Repair.
    Huang SN; Pommier Y
    Int J Mol Sci; 2019 Jun; 20(12):. PubMed ID: 31226795
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Tyrosyl-DNA-phosphodiesterase I (TDP1) participates in the removal and repair of stabilized-Top2α cleavage complexes in human cells.
    Borda MA; Palmitelli M; Verón G; González-Cid M; de Campos Nebel M
    Mutat Res; 2015 Nov; 781():37-48. PubMed ID: 26421495
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Trapped topoisomerase-DNA covalent complexes in the mitochondria and their role in human diseases.
    Das BB; Ghosh A; Bhattacharjee S; Bhattacharyya A
    Mitochondrion; 2021 Sep; 60():234-244. PubMed ID: 34500116
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions.
    Plo I; Liao ZY; Barceló JM; Kohlhagen G; Caldecott KW; Weinfeld M; Pommier Y
    DNA Repair (Amst); 2003 Oct; 2(10):1087-100. PubMed ID: 13679147
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Novel TDP2-ubiquitin interactions and their importance for the repair of topoisomerase II-mediated DNA damage.
    Rao T; Gao R; Takada S; Al Abo M; Chen X; Walters KJ; Pommier Y; Aihara H
    Nucleic Acids Res; 2016 Dec; 44(21):10201-10215. PubMed ID: 27543075
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.
    Liu C; Pouliot JJ; Nash HA
    Proc Natl Acad Sci U S A; 2002 Nov; 99(23):14970-5. PubMed ID: 12397185
    [TBL] [Abstract][Full Text] [Related]  

  • 29. [Tyrosyl-DNA phosphodiesterases: potential targets for cancer treatment].
    Hu Z; Wang HW; An LK
    Yao Xue Xue Bao; 2016 Feb; 51(2):215-25. PubMed ID: 29856574
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Discovery, enantioselective synthesis of myrtucommulone E analogues as tyrosyl-DNA phosphodiesterase 2 inhibitors and their biological activities.
    Zhang Y; Yang H; Wang FT; Peng X; Liu HY; Li QJ; An LK
    Eur J Med Chem; 2022 Aug; 238():114445. PubMed ID: 35580424
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1.
    Zakharenko AL; Luzina OA; Chepanova AA; Dyrkheeva NS; Salakhutdinov NF; Lavrik OI
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982848
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Tyrosyl-DNA phosphodiesterase 1 (TDP1) and SPRTN protease repair histone 3 and topoisomerase 1 DNA-protein crosslinks
    Anticevic I; Otten C; Vinkovic L; Jukic L; Popovic M
    Open Biol; 2023 Oct; 13(10):230113. PubMed ID: 37788708
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways.
    Sun Y; Saha LK; Saha S; Jo U; Pommier Y
    DNA Repair (Amst); 2020 Oct; 94():102926. PubMed ID: 32674013
    [TBL] [Abstract][Full Text] [Related]  

  • 34. TDP1 knockout Leishmania donovani accumulate topoisomerase 1-linked DNA damage and are hypersensitive to clinically used antileishmanial drugs.
    Chowdhury SR; Das SK; Banerjee B; Paul Chowdhuri S; Majumder HK; Das BB
    FASEB J; 2022 Apr; 36(4):e22265. PubMed ID: 35319800
    [TBL] [Abstract][Full Text] [Related]  

  • 35. TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.
    Zeng Z; Cortés-Ledesma F; El Khamisy SF; Caldecott KW
    J Biol Chem; 2011 Jan; 286(1):403-9. PubMed ID: 21030584
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Correlation between topoisomerase I and tyrosyl-DNA phosphodiesterase 1 activities in non-small cell lung cancer tissue.
    Jakobsen AK; Lauridsen KL; Samuel EB; Proszek J; Knudsen BR; Hager H; Stougaard M
    Exp Mol Pathol; 2015 Aug; 99(1):56-64. PubMed ID: 25987486
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents.
    Zhang XR; Wang HW; Tang WL; Zhang Y; Yang H; Hu DX; Ravji A; Marchand C; Kiselev E; Ofori-Atta K; Agama K; Pommier Y; An LK
    J Med Chem; 2018 Nov; 61(22):9908-9930. PubMed ID: 30336023
    [TBL] [Abstract][Full Text] [Related]  

  • 38. ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells.
    Bian K; Muppani NR; Elkhadragy L; Wang W; Zhang C; Chen T; Jung S; Seternes OM; Long W
    Oncotarget; 2016 Feb; 7(6):6665-75. PubMed ID: 26701725
    [TBL] [Abstract][Full Text] [Related]  

  • 39. MUS81 cleaves TOP1-derived lesions and other DNA-protein cross-links.
    Marini V; Nikulenkov F; Samadder P; Juul S; Knudsen BR; Krejci L
    BMC Biol; 2023 May; 21(1):110. PubMed ID: 37194054
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes.
    Lee KC; Swan RL; Sondka Z; Padget K; Cowell IG; Austin CA
    Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30011940
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.