BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 35101976)

  • 1. The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice.
    Yu H; Luo H; Chang L; Wang S; Geng X; Kang L; Zhong Y; Cao Y; Wang R; Yang X; Zhu Y; Shi MJ; Hu Y; Liu Z; Yin X; Ran Y; Yang H; Fan W; Zhao BQ
    Proc Natl Acad Sci U S A; 2022 Feb; 119(6):. PubMed ID: 35101976
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells.
    Wang Y; Luo Z; Pan Y; Wang W; Zhou X; Jeong LS; Chu Y; Liu J; Jia L
    Cancer Biol Ther; 2015; 16(3):420-9. PubMed ID: 25782162
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neddylation in the chronically hypoperfused corpus callosum: MLN4924 reduces blood-brain barrier injury via ERK5/KLF2 signaling.
    Yang X; Chang L; Liu Z; Geng X; Wang R; Yin X; Fan W; Zhao BQ
    Exp Neurol; 2024 Jan; 371():114587. PubMed ID: 37914067
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
    Lan H; Tang Z; Jin H; Sun Y
    Sci Rep; 2016 Apr; 6():24218. PubMed ID: 27063292
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibiting Neddylation with MLN4924 Suppresses Growth and Delays Multicellular Development in
    Huber RJ; Kim WD; Mathavarajah S
    Biomolecules; 2021 Mar; 11(3):. PubMed ID: 33807046
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MLN4924 is an efficient inhibitor of NEDD8 conjugation in plants.
    Hakenjos JP; Richter R; Dohmann EM; Katsiarimpa A; Isono E; Schwechheimer C
    Plant Physiol; 2011 Jun; 156(2):527-36. PubMed ID: 21527421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nedd8-Activating Enzyme Is a Druggable Host Dependency Factor of Human and Mouse Cytomegalovirus.
    Flores-Martínez YA; Le-Trilling VTK; Trilling M
    Viruses; 2021 Aug; 13(8):. PubMed ID: 34452475
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells.
    Luo Z; Pan Y; Jeong LS; Liu J; Jia L
    Autophagy; 2012 Nov; 8(11):1677-9. PubMed ID: 22874562
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma.
    Tong S; Si Y; Yu H; Zhang L; Xie P; Jiang W
    Sci Rep; 2017 Jul; 7(1):5599. PubMed ID: 28717191
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of neddylation induces mitotic defects and alters MKLP1 accumulation at the midbody during cytokinesis.
    Chung D; Salsman J; Dellaire G
    Cell Cycle; 2019 May; 18(10):1135-1153. PubMed ID: 31057046
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cullin neddylation inhibitor attenuates hyperglycemia by enhancing hepatic insulin signaling through insulin receptor substrate stabilization.
    Chen C; Gu L; Matye DJ; Clayton YD; Hasan MN; Wang Y; Friedman JE; Li T
    Proc Natl Acad Sci U S A; 2022 Feb; 119(6):. PubMed ID: 35115401
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Validation of NEDD8-conjugating enzyme UBC12 as a new therapeutic target in lung cancer.
    Li L; Kang J; Zhang W; Cai L; Wang S; Liang Y; Jiang Y; Liu X; Zhang Y; Ruan H; Chen G; Wang M; Jia L
    EBioMedicine; 2019 Jul; 45():81-91. PubMed ID: 31208947
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of neddylation represses lipopolysaccharide-induced proinflammatory cytokine production in macrophage cells.
    Chang FM; Reyna SM; Granados JC; Wei SJ; Innis-Whitehouse W; Maffi SK; Rodriguez E; Slaga TJ; Short JD
    J Biol Chem; 2012 Oct; 287(42):35756-35767. PubMed ID: 22927439
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Suppression of tumor angiogenesis by targeting the protein neddylation pathway.
    Yao WT; Wu JF; Yu GY; Wang R; Wang K; Li LH; Chen P; Jiang YN; Cheng H; Lee HW; Yu J; Qi H; Yu XJ; Wang P; Chu YW; Yang M; Hua ZC; Ying HQ; Hoffman RM; Jeong LS; Jia LJ
    Cell Death Dis; 2014 Feb; 5(2):e1059. PubMed ID: 24525735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting Protein Neddylation for Cancer Therapy.
    Zhou L; Jia L
    Adv Exp Med Biol; 2020; 1217():297-315. PubMed ID: 31898235
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neddylation-Independent Activities of MLN4924.
    Mao H; Sun Y
    Adv Exp Med Biol; 2020; 1217():363-372. PubMed ID: 31898238
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of p21-dependent senescence by an NAE inhibitor, MLN4924, as a mechanism of growth suppression.
    Jia L; Li H; Sun Y
    Neoplasia; 2011 Jun; 13(6):561-9. PubMed ID: 21677879
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MLN4924 suppresses neddylation and induces cell cycle arrest, senescence, and apoptosis in human osteosarcoma.
    Zhang Y; Shi CC; Zhang HP; Li GQ; Li SS
    Oncotarget; 2016 Jul; 7(29):45263-45274. PubMed ID: 27223074
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overactivated neddylation pathway as a therapeutic target in lung cancer.
    Li L; Wang M; Yu G; Chen P; Li H; Wei D; Zhu J; Xie L; Jia H; Shi J; Li C; Yao W; Wang Y; Gao Q; Jeong LS; Lee HW; Yu J; Hu F; Mei J; Wang P; Chu Y; Qi H; Yang M; Dong Z; Sun Y; Hoffman RM; Jia L
    J Natl Cancer Inst; 2014 Jun; 106(6):dju083. PubMed ID: 24853380
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer.
    Pan WW; Zhou JJ; Yu C; Xu Y; Guo LJ; Zhang HY; Zhou D; Song FZ; Fan HY
    J Biol Chem; 2013 Oct; 288(41):29680-91. PubMed ID: 23995842
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.