BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 35104611)

  • 1. Unusual commonality in active site structural features of substrate promiscuous and specialist enzymes.
    Thakur D; Pandit SB
    J Struct Biol; 2022 Mar; 214(1):107835. PubMed ID: 35104611
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular signatures-based prediction of enzyme promiscuity.
    Carbonell P; Faulon JL
    Bioinformatics; 2010 Aug; 26(16):2012-9. PubMed ID: 20551137
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase.
    Wang C; Liu C; Zhu X; Peng Q; Ma Q
    Nat Commun; 2023 Aug; 14(1):4795. PubMed ID: 37558668
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enzyme promiscuity: mechanism and applications.
    Hult K; Berglund P
    Trends Biotechnol; 2007 May; 25(5):231-8. PubMed ID: 17379338
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enzyme promiscuity: a mechanistic and evolutionary perspective.
    Khersonsky O; Tawfik DS
    Annu Rev Biochem; 2010; 79():471-505. PubMed ID: 20235827
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Shining a light on enzyme promiscuity.
    Copley SD
    Curr Opin Struct Biol; 2017 Dec; 47():167-175. PubMed ID: 29169066
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Promiscuity in the Enzymatic Catalysis of Phosphate and Sulfate Transfer.
    Pabis A; Duarte F; Kamerlin SC
    Biochemistry; 2016 Jun; 55(22):3061-81. PubMed ID: 27187273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A quantitative index of substrate promiscuity.
    Nath A; Atkins WM
    Biochemistry; 2008 Jan; 47(1):157-66. PubMed ID: 18081310
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Catalytic and binding poly-reactivities shared by two unrelated proteins: The potential role of promiscuity in enzyme evolution.
    James LC; Tawfik DS
    Protein Sci; 2001 Dec; 10(12):2600-7. PubMed ID: 11714928
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanisms of promiscuity among drug metabolizing enzymes and drug transporters.
    Atkins WM
    FEBS J; 2020 Apr; 287(7):1306-1322. PubMed ID: 31663687
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enzyme Promiscuous Activity: How to Define it and its Evolutionary Aspects.
    De Luca V; Mandrich L
    Protein Pept Lett; 2020; 27(5):400-410. PubMed ID: 31868141
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An evolutionary biochemist's perspective on promiscuity.
    Copley SD
    Trends Biochem Sci; 2015 Feb; 40(2):72-8. PubMed ID: 25573004
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Facilitating the Evolution of Esterase Activity from a Promiscuous Enzyme (Mhg) with Catalytic Functions of Amide Hydrolysis and Carboxylic Acid Perhydrolysis by Engineering the Substrate Entrance Tunnel.
    Yan X; Wang J; Sun Y; Zhu J; Wu S
    Appl Environ Microbiol; 2016 Nov; 82(22):6748-6756. PubMed ID: 27613682
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Catalytic promiscuity of the non-native FPP substrate in the TEAS enzyme: non-negligible flexibility of the carbocation intermediate.
    Zhang F; Wang YH; Tang X; Wu R
    Phys Chem Chem Phys; 2018 Jun; 20(22):15061-15073. PubMed ID: 29790522
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential catalytic promiscuity of the alkaline phosphatase superfamily bimetallo core reveals mechanistic features underlying enzyme evolution.
    Sunden F; AlSadhan I; Lyubimov A; Doukov T; Swan J; Herschlag D
    J Biol Chem; 2017 Dec; 292(51):20960-20974. PubMed ID: 29070681
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The mechanistic insights into different aspects of promiscuity in metalloenzymes.
    Tripathi A; Dubey KD
    Adv Protein Chem Struct Biol; 2024; 141():23-66. PubMed ID: 38960476
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enzyme promiscuity: evolutionary and mechanistic aspects.
    Khersonsky O; Roodveldt C; Tawfik DS
    Curr Opin Chem Biol; 2006 Oct; 10(5):498-508. PubMed ID: 16939713
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Catalytic and substrate promiscuity: distinct multiple chemistries catalysed by the phosphatase domain of receptor protein tyrosine phosphatase.
    Srinivasan B; Marks H; Mitra S; Smalley DM; Skolnick J
    Biochem J; 2016 Jul; 473(14):2165-77. PubMed ID: 27208174
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evolution of conformational dynamics determines the conversion of a promiscuous generalist into a specialist enzyme.
    Zou T; Risso VA; Gavira JA; Sanchez-Ruiz JM; Ozkan SB
    Mol Biol Evol; 2015 Jan; 32(1):132-43. PubMed ID: 25312912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stochastic ensembles, conformationally adaptive teamwork, and enzymatic detoxification.
    Atkins WM; Qian H
    Biochemistry; 2011 May; 50(19):3866-72. PubMed ID: 21473615
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.