133 related articles for article (PubMed ID: 35104620)
1. Current developments in extracellular-regulated protein kinase (ERK1/2) inhibitors.
Niu Y; Ji H
Drug Discov Today; 2022 May; 27(5):1464-1473. PubMed ID: 35104620
[TBL] [Abstract][Full Text] [Related]
2. Targeting Extracellular Signal-Regulated Protein Kinase 1/2 (ERK1/2) in Cancer: An Update on Pharmacological Small-Molecule Inhibitors.
Fu L; Chen S; He G; Chen Y; Liu B
J Med Chem; 2022 Oct; 65(20):13561-13573. PubMed ID: 36205714
[TBL] [Abstract][Full Text] [Related]
3. Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1.
Kogut MH; Genovese KJ; He H
Mol Immunol; 2007 Mar; 44(7):1729-36. PubMed ID: 17045653
[TBL] [Abstract][Full Text] [Related]
4. Targeting ERK1/2 protein-serine/threonine kinases in human cancers.
Roskoski R
Pharmacol Res; 2019 Apr; 142():151-168. PubMed ID: 30794926
[TBL] [Abstract][Full Text] [Related]
5. Development of extracellular signal-regulated kinase inhibitors.
Burkhard K; Smith S; Deshmukh R; MacKerell AD; Shapiro P
Curr Top Med Chem; 2009; 9(8):678-89. PubMed ID: 19689374
[TBL] [Abstract][Full Text] [Related]
6. Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer.
Liu B; Fu L; Zhang C; Zhang L; Zhang Y; Ouyang L; He G; Huang J
Oncotarget; 2015 Mar; 6(9):6762-75. PubMed ID: 25742792
[TBL] [Abstract][Full Text] [Related]
7. Identification of novel extracellular signal-regulated kinase docking domain inhibitors.
Hancock CN; Macias A; Lee EK; Yu SY; Mackerell AD; Shapiro P
J Med Chem; 2005 Jul; 48(14):4586-95. PubMed ID: 15999996
[TBL] [Abstract][Full Text] [Related]
8. Parallel signaling pathways in endothelin-1-induced proliferation of U373MG astrocytoma cells.
He S; Dibas A; Yorio T; Prasanna G
Exp Biol Med (Maywood); 2007 Mar; 232(3):370-84. PubMed ID: 17327470
[TBL] [Abstract][Full Text] [Related]
9. Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy.
Tong Z; Singh G; Rainbow AJ
Cancer Res; 2002 Oct; 62(19):5528-35. PubMed ID: 12359764
[TBL] [Abstract][Full Text] [Related]
10. Nitric oxide and cGMP activate the Ras-MAP kinase pathway-stimulating protein tyrosine phosphorylation in rabbit aortic endothelial cells.
Oliveira CJ; Schindler F; Ventura AM; Morais MS; Arai RJ; Debbas V; Stern A; Monteiro HP
Free Radic Biol Med; 2003 Aug; 35(4):381-96. PubMed ID: 12899940
[TBL] [Abstract][Full Text] [Related]
11. cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner.
Hecquet C; Lefevre G; Valtink M; Engelmann K; Mascarelli F
Oncogene; 2002 Sep; 21(39):6101-12. PubMed ID: 12203122
[TBL] [Abstract][Full Text] [Related]
12. Prolonged extracellular signal-regulated kinase 1/2 activation during fibroblast growth factor 1- or heregulin beta1-induced antiestrogen-resistant growth of breast cancer cells is resistant to mitogen-activated protein/extracellular regulated kinase kinase inhibitors.
Thottassery JV; Sun Y; Westbrook L; Rentz SS; Manuvakhova M; Qu Z; Samuel S; Upshaw R; Cunningham A; Kern FG
Cancer Res; 2004 Jul; 64(13):4637-47. PubMed ID: 15231676
[TBL] [Abstract][Full Text] [Related]
13. Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells.
Lall MM; Harned J; McGahan MC
Mol Vis; 2013; 19():2106-12. PubMed ID: 24146543
[TBL] [Abstract][Full Text] [Related]
14. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.
Roberts PJ; Der CJ
Oncogene; 2007 May; 26(22):3291-310. PubMed ID: 17496923
[TBL] [Abstract][Full Text] [Related]
15. The RAF-MEK-ERK pathway: targeting ERK to overcome obstacles to effective cancer therapy.
Yu Z; Ye S; Hu G; Lv M; Tu Z; Zhou K; Li Q
Future Med Chem; 2015; 7(3):269-89. PubMed ID: 25826360
[TBL] [Abstract][Full Text] [Related]
16. Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells.
Basken J; Stuart SA; Kavran AJ; Lee T; Ebmeier CC; Old WM; Ahn NG
Mol Cell Proteomics; 2018 Apr; 17(4):550-564. PubMed ID: 29255136
[TBL] [Abstract][Full Text] [Related]
17. Extracellular signal-regulated kinases (ERKs) pathway and reactive oxygen species regulate tyrosine phosphorylation in capacitating boar spermatozoa.
Awda BJ; Buhr MM
Biol Reprod; 2010 Nov; 83(5):750-8. PubMed ID: 20592309
[TBL] [Abstract][Full Text] [Related]
18. Rational Design and Synthesis of Diverse Pyrimidine Molecules Bearing Sulfonamide Moiety as Novel ERK Inhibitors.
Halawa AH; Eskandrani AA; Elgammal WE; Hassan SM; Hassan AH; Ebrahim HY; Mehany ABM; El-Agrody AM; Okasha RM
Int J Mol Sci; 2019 Nov; 20(22):. PubMed ID: 31717402
[TBL] [Abstract][Full Text] [Related]
19. Constitutively active Ras negatively regulates Erk MAP kinase through induction of MAP kinase phosphatase 3 (MKP3) in NIH3T3 cells.
Park YJ; Lee JM; Shin SY; Kim YH
BMB Rep; 2014 Dec; 47(12):685-90. PubMed ID: 24602610
[TBL] [Abstract][Full Text] [Related]
20. Protein Kinase CK2α Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2α Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ERK in BRAF Mutant Melanoma.
Zhou B; Ritt DA; Morrison DK; Der CJ; Cox AD
J Biol Chem; 2016 Aug; 291(34):17804-15. PubMed ID: 27226552
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]