BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

347 related articles for article (PubMed ID: 35119166)

  • 1. BACE1: More than just a β-secretase.
    Taylor HA; Przemylska L; Clavane EM; Meakin PJ
    Obes Rev; 2022 Jul; 23(7):e13430. PubMed ID: 35119166
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuronal human BACE1 knockin induces systemic diabetes in mice.
    Plucińska K; Dekeryte R; Koss D; Shearer K; Mody N; Whitfield PD; Doherty MK; Mingarelli M; Welch A; Riedel G; Delibegovic M; Platt B
    Diabetologia; 2016 Jul; 59(7):1513-1523. PubMed ID: 27138913
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Control of β-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-λ/ι and Nuclear Factor κ-B.
    Sajan MP; Leitges M; Park C; Diamond DM; Wu J; Hansen BC; Duncan MA; Apostolatos CA; Apostolatos AH; Kindy M; Farese RV
    Curr Alzheimer Res; 2021; 18(12):941-955. PubMed ID: 34951366
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo.
    Hirata-Fukae C; Sidahmed EH; Gooskens TP; Aisen PS; Dewachter I; Devijver H; Van Leuven F; Matsuoka Y
    Neurosci Lett; 2008 Apr; 435(3):186-9. PubMed ID: 18343582
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.
    Chen Y; Huang X; Zhang YW; Rockenstein E; Bu G; Golde TE; Masliah E; Xu H
    J Neurosci; 2012 Aug; 32(33):11390-5. PubMed ID: 22895721
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The β-Secretase Enzyme BACE1: A Biochemical Enigma for Alzheimer's Disease.
    Shah H; Patel A; Parikh V; Nagani A; Bhimani B; Shah U; Bambharoliya T
    CNS Neurol Disord Drug Targets; 2020; 19(3):184-194. PubMed ID: 32452328
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
    Chen CH; Zhou W; Liu S; Deng Y; Cai F; Tone M; Tone Y; Tong Y; Song W
    Int J Neuropsychopharmacol; 2012 Feb; 15(1):77-90. PubMed ID: 21329555
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered amyloid-beta metabolism and deposition in genomic-based beta-secretase transgenic mice.
    Chiocco MJ; Kulnane LS; Younkin L; Younkin S; Evin G; Lamb BT
    J Biol Chem; 2004 Dec; 279(50):52535-42. PubMed ID: 15452128
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.
    Maesako M; Uemura M; Tashiro Y; Sasaki K; Watanabe K; Noda Y; Ueda K; Asada-Utsugi M; Kubota M; Okawa K; Ihara M; Shimohama S; Uemura K; Kinoshita A
    PLoS One; 2015; 10(9):e0131199. PubMed ID: 26414661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
    Wang M; Jing T; Wang X; Yao D
    Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The BACE1-PSEN-AβPP regulatory axis has an ancient role in response to low oxygen/oxidative stress.
    Moussavi Nik SH; Wilson L; Newman M; Croft K; Mori TA; Musgrave I; Lardelli M
    J Alzheimers Dis; 2012; 28(3):515-30. PubMed ID: 22045484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BACE1: the beta-secretase enzyme in Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing.
    Zhao Y; Wang Y; Yang J; Wang X; Zhao Y; Zhang X; Zhang YW
    Mol Neurodegener; 2012 Jun; 7():30. PubMed ID: 22709416
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ
    J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
    Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC
    Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice.
    Devi L; Ohno M
    Eur J Neurosci; 2010 Jan; 31(1):110-8. PubMed ID: 20092558
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synaptic Vesicle Protein 2B Negatively Regulates the Amyloidogenic Processing of AβPP as a Novel Interaction Partner of BACE1.
    Miyamoto M; Kuzuya A; Noda Y; Ueda S; Asada-Utsugi M; Ito S; Fukusumi Y; Kawachi H; Takahashi R; Kinoshita A
    J Alzheimers Dis; 2020; 75(1):173-185. PubMed ID: 32280101
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clec4g (LSECtin) interacts with BACE1 and suppresses Aβ generation.
    Kizuka Y; Kitazume S; Sato K; Taniguchi N
    FEBS Lett; 2015 Jun; 589(13):1418-22. PubMed ID: 25957769
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.