These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 35121025)

  • 21. Progress in research on the role of Omi/HtrA2 in neurological diseases.
    Su XJ; Huang L; Qu Y; Mu D
    Rev Neurosci; 2019 Apr; 30(3):279-287. PubMed ID: 30205651
    [TBL] [Abstract][Full Text] [Related]  

  • 22. HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.
    Verhagen AM; Silke J; Ekert PG; Pakusch M; Kaufmann H; Connolly LM; Day CL; Tikoo A; Burke R; Wrobel C; Moritz RL; Simpson RJ; Vaux DL
    J Biol Chem; 2002 Jan; 277(1):445-54. PubMed ID: 11604410
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Structural basis of substrate recognition and allosteric activation of the proapoptotic mitochondrial HtrA2 protease.
    Aspholm EE; Lidman J; Burmann BM
    Nat Commun; 2024 May; 15(1):4592. PubMed ID: 38816423
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Dissecting the role of interprotomer cooperativity in the activation of oligomeric high-temperature requirement A2 protein.
    Toyama Y; Harkness RW; Kay LE
    Proc Natl Acad Sci U S A; 2021 Aug; 118(35):. PubMed ID: 34446566
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The serine protease HtrA2 cleaves UCH-L1 and inhibits its hydrolase activity: implication in the UCH-L1-mediated cell death.
    Park DW; Nam MK; Rhim H
    Biochem Biophys Res Commun; 2011 Nov; 415(1):24-9. PubMed ID: 22001920
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes.
    Rodrigue-Gervais IG; Doiron K; Champagne C; Mayes L; Leiva-Torres GA; Vanié P; Douglas T; Vidal SM; Alnemri ES; Saleh M
    Sci Rep; 2018 May; 8(1):8446. PubMed ID: 29855523
    [TBL] [Abstract][Full Text] [Related]  

  • 27. YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways.
    Li H; He F; Zhao X; Zhang Y; Chu X; Hua C; Qu Y; Duan Y; Ming L
    Cell Physiol Biochem; 2017; 44(5):2073-2089. PubMed ID: 29241219
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi.
    Martins LM; Turk BE; Cowling V; Borg A; Jarrell ET; Cantley LC; Downward J
    J Biol Chem; 2003 Dec; 278(49):49417-27. PubMed ID: 14512424
    [TBL] [Abstract][Full Text] [Related]  

  • 29. HtrA2 regulates α-Synuclein-mediated mitochondrial reactive oxygen species production in the mitochondria of microglia.
    Nam MK; Seong Y; Jeong GH; Yoo SA; Rhim H
    Biochem Biophys Res Commun; 2023 Jan; 638():84-93. PubMed ID: 36442236
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Autocatalytic processing of HtrA2/Omi is essential for induction of caspase-dependent cell death through antagonizing XIAP.
    Seong YM; Choi JY; Park HJ; Kim KJ; Ahn SG; Seong GH; Kim IK; Kang S; Rhim H
    J Biol Chem; 2004 Sep; 279(36):37588-96. PubMed ID: 15201285
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structural basis of inactivation of human counterpart of mouse motor neuron degeneration 2 mutant in serine protease HtrA2.
    Wagh AR; Bose K
    Biosci Rep; 2018 Oct; 38(5):. PubMed ID: 30068699
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Translocation of the serine protease Omi/HtrA2 from mitochondria into the cytosol upon seizure-induced hippocampal injury in the neonatal rat brain.
    Rami A; Kim M; Niquet J
    Neurochem Res; 2010 Dec; 35(12):2199-207. PubMed ID: 21132459
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.
    Botham A; Coyaud E; Nirmalanandhan VS; Gronda M; Hurren R; Maclean N; St-Germain J; Mirali S; Laurent E; Raught B; Schimmer A
    Proteomics; 2019 Dec; 19(24):e1900139. PubMed ID: 31617661
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15.
    Trencia A; Fiory F; Maitan MA; Vito P; Barbagallo AP; Perfetti A; Miele C; Ungaro P; Oriente F; Cilenti L; Zervos AS; Formisano P; Beguinot F
    J Biol Chem; 2004 Nov; 279(45):46566-72. PubMed ID: 15328349
    [TBL] [Abstract][Full Text] [Related]  

  • 35. THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death.
    Balakrishnan MP; Cilenti L; Mashak Z; Popat P; Alnemri ES; Zervos AS
    Am J Physiol Heart Circ Physiol; 2009 Aug; 297(2):H643-53. PubMed ID: 19502560
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif.
    Martins LM; Iaccarino I; Tenev T; Gschmeissner S; Totty NF; Lemoine NR; Savopoulos J; Gray CW; Creasy CL; Dingwall C; Downward J
    J Biol Chem; 2002 Jan; 277(1):439-44. PubMed ID: 11602612
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cardiac Specific Overexpression of Mitochondrial Omi/HtrA2 Induces Myocardial Apoptosis and Cardiac Dysfunction.
    Wang K; Yuan Y; Liu X; Lau WB; Zuo L; Wang X; Ma L; Jiao K; Shang J; Wang W; Ma X; Liu H
    Sci Rep; 2016 Dec; 6():37927. PubMed ID: 27924873
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Mitochondrial serine protease HtrA2/Omi as a potential therapeutic target.
    Bhuiyan MS; Fukunaga K
    Curr Drug Targets; 2009 Apr; 10(4):372-83. PubMed ID: 19355862
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease.
    Krick S; Shi S; Ju W; Faul C; Tsai SY; Mundel P; Böttinger EP
    Proc Natl Acad Sci U S A; 2008 Sep; 105(37):14106-11. PubMed ID: 18772386
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
    Merski M; Moreira C; Abreu RM; Ramos MJ; Fernandes PA; Martins LM; Pereira PJB; Macedo-Ribeiro S
    Cell Death Dis; 2017 Oct; 8(10):e3119. PubMed ID: 29022916
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.