These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
256 related articles for article (PubMed ID: 35138624)
1. The Functional Properties, Physiological Roles, Channelopathy and Pharmacological Characteristics of the Slack (KCNT1) Channel. Zhang Q; Liu Y; Xu J; Teng Y; Zhang Z Adv Exp Med Biol; 2021; 1349():387-400. PubMed ID: 35138624 [TBL] [Abstract][Full Text] [Related]
2. Functional evaluation of epilepsy-associated KCNT1 variants in multiple cellular systems reveals a predominant gain of function impact on channel properties. Hinckley CA; Zhu Z; Chu JH; Gubbels C; Danker T; Cherry JJ; Whelan CD; Engle SJ; Nguyen V Epilepsia; 2023 Aug; 64(8):2126-2136. PubMed ID: 37177976 [TBL] [Abstract][Full Text] [Related]
3. Potassium channelopathies associated with epilepsy-related syndromes and directions for therapeutic intervention. Gribkoff VK; Winquist RJ Biochem Pharmacol; 2023 Feb; 208():115413. PubMed ID: 36646291 [TBL] [Abstract][Full Text] [Related]
4. The Phe932Ile mutation in KCNT1 channels associated with severe epilepsy, delayed myelination and leukoencephalopathy produces a loss-of-function channel phenotype. Evely KM; Pryce KD; Bhattacharjee A Neuroscience; 2017 May; 351():65-70. PubMed ID: 28366665 [TBL] [Abstract][Full Text] [Related]
6. Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons. Wu J; Quraishi IH; Zhang Y; Bromwich M; Kaczmarek LK Cell Rep; 2024 Mar; 43(3):113904. PubMed ID: 38457342 [TBL] [Abstract][Full Text] [Related]
7. New use for an old drug: quinidine in KCNT1-related epilepsy therapy. Liu R; Sun L; Wang Y; Wang Q; Wu J Neurol Sci; 2023 Apr; 44(4):1201-1206. PubMed ID: 36437393 [TBL] [Abstract][Full Text] [Related]
8. An Epilepsy-Associated KCNT1 Mutation Enhances Excitability of Human iPSC-Derived Neurons by Increasing Slack K Quraishi IH; Stern S; Mangan KP; Zhang Y; Ali SR; Mercier MR; Marchetto MC; McLachlan MJ; Jones EM; Gage FH; Kaczmarek LK J Neurosci; 2019 Sep; 39(37):7438-7449. PubMed ID: 31350261 [TBL] [Abstract][Full Text] [Related]
9. Two Patients With KCNT1-Related Epilepsy Responding to Phenobarbital and Potassium Bromide. Datta AN; Michoulas A; Guella I; ; Demos M J Child Neurol; 2019 Oct; 34(12):728-734. PubMed ID: 31208268 [No Abstract] [Full Text] [Related]
11. Impaired motor skill learning and altered seizure susceptibility in mice with loss or gain of function of the Kcnt1 gene encoding Slack (K Quraishi IH; Mercier MR; McClure H; Couture RL; Schwartz ML; Lukowski R; Ruth P; Kaczmarek LK Sci Rep; 2020 Feb; 10(1):3213. PubMed ID: 32081855 [TBL] [Abstract][Full Text] [Related]
12. KCNT1 mutations in seizure disorders: the phenotypic spectrum and functional effects. Lim CX; Ricos MG; Dibbens LM; Heron SE J Med Genet; 2016 Apr; 53(4):217-25. PubMed ID: 26740507 [TBL] [Abstract][Full Text] [Related]
13. Drosophila expressing mutant human KCNT1 transgenes make an effective tool for targeted drug screening in a whole animal model of KCNT1-epilepsy. Hussain R; Lim CX; Shaukat Z; Islam A; Caseley EA; Lippiat JD; Rychkov GY; Ricos MG; Dibbens LM Sci Rep; 2024 Feb; 14(1):3357. PubMed ID: 38336906 [TBL] [Abstract][Full Text] [Related]
14. K Gertler TS; Cherian S; DeKeyser JM; Kearney JA; George AL Neurobiol Dis; 2022 Jun; 168():105713. PubMed ID: 35346832 [TBL] [Abstract][Full Text] [Related]
15. Identification of a novel de novo p.Phe932Ile KCNT1 mutation in a patient with leukoencephalopathy and severe epilepsy. Vanderver A; Simons C; Schmidt JL; Pearl PL; Bloom M; Lavenstein B; Miller D; Grimmond SM; Taft RJ Pediatr Neurol; 2014 Jan; 50(1):112-4. PubMed ID: 24120652 [TBL] [Abstract][Full Text] [Related]
16. Carvedilol inhibits neuronal hyperexcitability caused by epilepsy-associated KCNT1 mutations. Di C; Wu T; Gao K; Li N; Song H; Wang L; Sun H; Yi J; Zhang X; Chen J; Shah M; Jiang Y; Huang Z Br J Pharmacol; 2025 Jan; 182(1):162-180. PubMed ID: 39370580 [TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685. Qunies AM; Spitznagel BD; Du Y; David Weaver C; Emmitte KA Bioorg Med Chem; 2023 Nov; 95():117487. PubMed ID: 37812884 [TBL] [Abstract][Full Text] [Related]
19. Phactr1 regulates Slack (KCNT1) channels via protein phosphatase 1 (PP1). Ali SR; Malone TJ; Zhang Y; Prechova M; Kaczmarek LK FASEB J; 2020 Jan; 34(1):1591-1601. PubMed ID: 31914597 [TBL] [Abstract][Full Text] [Related]
20. In silico model reveals the key role of GABA in KCNT1-epilepsy in infancy with migrating focal seizures. Kuchenbuch M; Nabbout R; Yochum M; Sauleau P; Modolo J; Wendling F; Benquet P Epilepsia; 2021 Mar; 62(3):683-697. PubMed ID: 33617692 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]