139 related articles for article (PubMed ID: 35142524)
1. Membrane Composition and Raf[CRD]-Membrane Attachment Are Driving Forces for K-Ras4B Dimer Stability.
Andreadelis I; Kiriakidi S; Lamprakis C; Theodoropoulou A; Doerr S; Chatzigoulas A; Manchester J; Velez-Vega C; Duca JS; Cournia Z
J Phys Chem B; 2022 Feb; 126(7):1504-1519. PubMed ID: 35142524
[TBL] [Abstract][Full Text] [Related]
2. Characterization of the Spatial Organization of Raf Isoforms Interacting with K-Ras4B in the Lipid Membrane.
Li L; Möbitz S; Winter R
Langmuir; 2020 Jun; 36(21):5944-5953. PubMed ID: 32390436
[TBL] [Abstract][Full Text] [Related]
3. Raf-1 Cysteine-Rich Domain Increases the Affinity of K-Ras/Raf at the Membrane, Promoting MAPK Signaling.
Li S; Jang H; Zhang J; Nussinov R
Structure; 2018 Mar; 26(3):513-525.e2. PubMed ID: 29429878
[TBL] [Abstract][Full Text] [Related]
4. How Anionic Lipids Affect Spatiotemporal Properties of KRAS4B on Model Membranes.
Ngo VA; Sarkar S; Neale C; Garcia AE
J Phys Chem B; 2020 Jul; 124(26):5434-5453. PubMed ID: 32438809
[TBL] [Abstract][Full Text] [Related]
5. A "Tug of War" Maintains a Dynamic Protein-Membrane Complex: Molecular Dynamics Simulations of C-Raf RBD-CRD Bound to K-Ras4B at an Anionic Membrane.
Li ZL; Prakash P; Buck M
ACS Cent Sci; 2018 Feb; 4(2):298-305. PubMed ID: 29532030
[TBL] [Abstract][Full Text] [Related]
6. Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling.
Muratcioglu S; Aydin C; Odabasi E; Ozdemir ES; Firat-Karalar EN; Jang H; Tsai CJ; Nussinov R; Kavakli IH; Gursoy A; Keskin O
J Mol Biol; 2020 Feb; 432(4):1199-1215. PubMed ID: 31931009
[TBL] [Abstract][Full Text] [Related]
7. Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
Mazhab-Jafari MT; Marshall CB; Smith MJ; Gasmi-Seabrook GM; Stathopulos PB; Inagaki F; Kay LE; Neel BG; Ikura M
Proc Natl Acad Sci U S A; 2015 May; 112(21):6625-30. PubMed ID: 25941399
[TBL] [Abstract][Full Text] [Related]
8. Anionic Lipids Impact RAS-Binding Site Accessibility and Membrane Binding Affinity of CRAF RBD-CRD.
Travers T; López CA; Agamasu C; Hettige JJ; Messing S; García AE; Stephen AG; Gnanakaran S
Biophys J; 2020 Aug; 119(3):525-538. PubMed ID: 32649863
[TBL] [Abstract][Full Text] [Related]
9. The higher level of complexity of K-Ras4B activation at the membrane.
Jang H; Banerjee A; Chavan TS; Lu S; Zhang J; Gaponenko V; Nussinov R
FASEB J; 2016 Apr; 30(4):1643-55. PubMed ID: 26718888
[TBL] [Abstract][Full Text] [Related]
10. Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.
Fang Z; Lee KY; Huo KG; Gasmi-Seabrook G; Zheng L; Moghal N; Tsao MS; Ikura M; Marshall CB
Proc Natl Acad Sci U S A; 2020 Jun; 117(22):12101-12108. PubMed ID: 32414921
[TBL] [Abstract][Full Text] [Related]
11. K-Ras G-domain binding with signaling lipid phosphatidylinositol (4,5)-phosphate (PIP2): membrane association, protein orientation, and function.
Cao S; Chung S; Kim S; Li Z; Manor D; Buck M
J Biol Chem; 2019 Apr; 294(17):7068-7084. PubMed ID: 30792310
[TBL] [Abstract][Full Text] [Related]
12. Methionine 170 is an Environmentally Sensitive Membrane Anchor in the Disordered HVR of K-Ras4B.
Neale C; García AE
J Phys Chem B; 2018 Nov; 122(44):10086-10096. PubMed ID: 30351122
[TBL] [Abstract][Full Text] [Related]
13. Insight into the mechanism of allosteric activation of PI3Kα by oncoprotein K-Ras4B.
Li X; Dai J; Ni D; He X; Zhang H; Zhang J; Fu Q; Liu Y; Lu S
Int J Biol Macromol; 2020 Feb; 144():643-655. PubMed ID: 31816384
[TBL] [Abstract][Full Text] [Related]
14. Mechanisms of membrane binding of small GTPase K-Ras4B farnesylated hypervariable region.
Jang H; Abraham SJ; Chavan TS; Hitchinson B; Khavrutskii L; Tarasova NI; Nussinov R; Gaponenko V
J Biol Chem; 2015 Apr; 290(15):9465-77. PubMed ID: 25713064
[TBL] [Abstract][Full Text] [Related]
15. Exploring CRD mobility during RAS/RAF engagement at the membrane.
Nguyen K; López CA; Neale C; Van QN; Carpenter TS; Di Natale F; Travers T; Tran TH; Chan AH; Bhatia H; Frank PH; Tonelli M; Zhang X; Gulten G; Reddy T; Burns V; Oppelstrup T; Hengartner N; Simanshu DK; Bremer PT; Chen D; Glosli JN; Shrestha R; Turbyville T; Streitz FH; Nissley DV; Ingólfsson HI; Stephen AG; Lightstone FC; Gnanakaran S
Biophys J; 2022 Oct; 121(19):3630-3650. PubMed ID: 35778842
[TBL] [Abstract][Full Text] [Related]
16. A novel prenyl-polybasic domain code determines lipid-binding specificity of the K-Ras membrane anchor.
Zhou Y; Hancock JF
Small GTPases; 2020 May; 11(3):220-224. PubMed ID: 29239694
[TBL] [Abstract][Full Text] [Related]
17. GTP-Dependent K-Ras Dimerization.
Muratcioglu S; Chavan TS; Freed BC; Jang H; Khavrutskii L; Freed RN; Dyba MA; Stefanisko K; Tarasov SG; Gursoy A; Keskin O; Tarasova NI; Gaponenko V; Nussinov R
Structure; 2015 Jul; 23(7):1325-35. PubMed ID: 26051715
[TBL] [Abstract][Full Text] [Related]
18. Molecular recognition of RAS/RAF complex at the membrane: Role of RAF cysteine-rich domain.
Travers T; López CA; Van QN; Neale C; Tonelli M; Stephen AG; Gnanakaran S
Sci Rep; 2018 May; 8(1):8461. PubMed ID: 29855542
[TBL] [Abstract][Full Text] [Related]
19. Flexible-body motions of calmodulin and the farnesylated hypervariable region yield a high-affinity interaction enabling K-Ras4B membrane extraction.
Jang H; Banerjee A; Chavan T; Gaponenko V; Nussinov R
J Biol Chem; 2017 Jul; 292(30):12544-12559. PubMed ID: 28623230
[TBL] [Abstract][Full Text] [Related]
20. Computational Modeling Reveals that Signaling Lipids Modulate the Orientation of K-Ras4A at the Membrane Reflecting Protein Topology.
Li ZL; Buck M
Structure; 2017 Apr; 25(4):679-689.e2. PubMed ID: 28286004
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]