These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 35143176)

  • 1. Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1.
    Liu WH; Miner RE; Albaugh BN; Ananiev GE; Wildman SA; Denu JM
    Biochemistry; 2022 Mar; 61(5):354-366. PubMed ID: 35143176
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein.
    Cheng J; Yang Y; Fang J; Xiao J; Zhu T; Chen F; Wang P; Li Z; Yang H; Xu Y
    J Biol Chem; 2013 Jan; 288(2):1329-39. PubMed ID: 23161542
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular investigation of the tandem Tudor domain and plant homeodomain histone binding domains of the epigenetic regulator UHRF2.
    Ginnard SM; Winkler AE; Mellado Fritz C; Bluhm T; Kemmer R; Gilliam M; Butkevich N; Abdrabbo S; Bricker K; Feiler J; Miller I; Zoerman J; El-Mohri Z; Khuansanguan P; Basch M; Petzold T; Kostoff M; Konopka S; Kociba B; Gillis T; Heyl DL; Trievel RC; Albaugh BN
    Proteins; 2022 Mar; 90(3):835-847. PubMed ID: 34766381
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells.
    Vaughan RM; Kupai A; Foley CA; Sagum CA; Tibben BM; Eden HE; Tiedemann RL; Berryhill CA; Patel V; Shaw KM; Krajewski K; Strahl BD; Bedford MT; Frye SV; Dickson BM; Rothbart SB
    Epigenetics Chromatin; 2020 Oct; 13(1):44. PubMed ID: 33097091
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation.
    Vaughan RM; Rothbart SB; Dickson BM
    J Biol Chem; 2019 Oct; 294(43):15724-15732. PubMed ID: 31481468
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stella protein facilitates DNA demethylation by disrupting the chromatin association of the RING finger-type E3 ubiquitin ligase UHRF1.
    Du W; Dong Q; Zhang Z; Liu B; Zhou T; Xu RM; Wang H; Zhu B; Li Y
    J Biol Chem; 2019 May; 294(22):8907-8917. PubMed ID: 31018966
    [No Abstract]   [Full Text] [Related]  

  • 7. Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation.
    Rothbart SB; Dickson BM; Ong MS; Krajewski K; Houliston S; Kireev DB; Arrowsmith CH; Strahl BD
    Genes Dev; 2013 Jun; 27(11):1288-98. PubMed ID: 23752590
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers.
    Lallous N; Legrand P; McEwen AG; Ramón-Maiques S; Samama JP; Birck C
    PLoS One; 2011; 6(11):e27599. PubMed ID: 22096602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger.
    Hata K; Kobayashi N; Sugimura K; Qin W; Haxholli D; Chiba Y; Yoshimi S; Hayashi G; Onoda H; Ikegami T; Mulholland CB; Nishiyama A; Nakanishi M; Leonhardt H; Konuma T; Arita K
    Nucleic Acids Res; 2022 Nov; 50(21):12527-12542. PubMed ID: 36420895
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.
    Harrison JS; Cornett EM; Goldfarb D; DaRosa PA; Li ZM; Yan F; Dickson BM; Guo AH; Cantu DV; Kaustov L; Brown PJ; Arrowsmith CH; Erie DA; Major MB; Klevit RE; Krajewski K; Kuhlman B; Strahl BD; Rothbart SB
    Elife; 2016 Sep; 5():. PubMed ID: 27595565
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression.
    Rajakumara E; Wang Z; Ma H; Hu L; Chen H; Lin Y; Guo R; Wu F; Li H; Lan F; Shi YG; Xu Y; Patel DJ; Shi Y
    Mol Cell; 2011 Jul; 43(2):275-284. PubMed ID: 21777816
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increasing role of UHRF1 in the reading and inheritance of the epigenetic code as well as in tumorogenesis.
    Bronner C; Krifa M; Mousli M
    Biochem Pharmacol; 2013 Dec; 86(12):1643-9. PubMed ID: 24134914
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward Chromatin.
    Foster BM; Stolz P; Mulholland CB; Montoya A; Kramer H; Bultmann S; Bartke T
    Mol Cell; 2018 Nov; 72(4):739-752.e9. PubMed ID: 30392929
    [TBL] [Abstract][Full Text] [Related]  

  • 14. UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail.
    Xie S; Jakoncic J; Qian C
    J Mol Biol; 2012 Jan; 415(2):318-28. PubMed ID: 22100450
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation.
    DaRosa PA; Harrison JS; Zelter A; Davis TN; Brzovic P; Kuhlman B; Klevit RE
    Mol Cell; 2018 Nov; 72(4):753-765.e6. PubMed ID: 30392931
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.
    Rothbart SB; Krajewski K; Nady N; Tempel W; Xue S; Badeaux AI; Barsyte-Lovejoy D; Martinez JY; Bedford MT; Fuchs SM; Arrowsmith CH; Strahl BD
    Nat Struct Mol Biol; 2012 Nov; 19(11):1155-60. PubMed ID: 23022729
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1.
    Arita K; Isogai S; Oda T; Unoki M; Sugita K; Sekiyama N; Kuwata K; Hamamoto R; Tochio H; Sato M; Ariyoshi M; Shirakawa M
    Proc Natl Acad Sci U S A; 2012 Aug; 109(32):12950-5. PubMed ID: 22837395
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain.
    Senisterra G; Zhu HY; Luo X; Zhang H; Xun G; Lu C; Xiao W; Hajian T; Loppnau P; Chau I; Li F; Allali-Hassani A; Atadja P; Oyang C; Li E; Brown PJ; Arrowsmith CH; Zhao K; Yu Z; Vedadi M
    SLAS Discov; 2018 Oct; 23(9):930-940. PubMed ID: 29562800
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance.
    Vaughan RM; Dickson BM; Cornett EM; Harrison JS; Kuhlman B; Rothbart SB
    Nucleic Acids Res; 2018 May; 46(9):4405-4416. PubMed ID: 29506131
    [TBL] [Abstract][Full Text] [Related]  

  • 20. UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.
    Jin W; Chen L; Chen Y; Xu SG; Di GH; Yin WJ; Wu J; Shao ZM
    Breast Cancer Res Treat; 2010 Sep; 123(2):359-73. PubMed ID: 19943104
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.