181 related articles for article (PubMed ID: 35171398)
1. Saikosaponin B1 and Saikosaponin D inhibit tumor growth in medulloblastoma allograft mice via inhibiting the Hedgehog signaling pathway.
Luo J; Wang J; Yang J; Huang W; Liu J; Tan W; Xin H
J Nat Med; 2022 Jun; 76(3):584-593. PubMed ID: 35171398
[TBL] [Abstract][Full Text] [Related]
2. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway.
Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X
Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899
[TBL] [Abstract][Full Text] [Related]
3. Saikosaponin B2 attenuates kidney fibrosis via inhibiting the Hedgehog Pathway.
Ren D; Luo J; Li Y; Zhang J; Yang J; Liu J; Zhang X; Cheng N; Xin H
Phytomedicine; 2020 Feb; 67():153163. PubMed ID: 31901891
[TBL] [Abstract][Full Text] [Related]
4. Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells.
Scheidt T; Alka O; Gonczarowska-Jorge H; Gruber W; Rathje F; Dell'Aica M; Rurik M; Kohlbacher O; Zahedi RP; Aberger F; Huber CG
Cell Commun Signal; 2020 Jun; 18(1):99. PubMed ID: 32576205
[TBL] [Abstract][Full Text] [Related]
5. Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures.
Cohen JR; Resnick DZ; Niewiadomski P; Dong H; Liau LM; Waschek JA
BMC Cancer; 2010 Dec; 10():676. PubMed ID: 21143927
[TBL] [Abstract][Full Text] [Related]
6. β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.
Miele E; Po A; Begalli F; Antonucci L; Mastronuzzi A; Marras CE; Carai A; Cucchi D; Abballe L; Besharat ZM; Catanzaro G; Infante P; Di Marcotullio L; Canettieri G; De Smaele E; Screpanti I; Locatelli F; Ferretti E
BMC Cancer; 2017 Jul; 17(1):488. PubMed ID: 28716052
[TBL] [Abstract][Full Text] [Related]
7. The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.
Scicchitano S; Giordano M; Lucchino V; Montalcini Y; Chiarella E; Aloisio A; Codispoti B; Zoppoli P; Melocchi V; Bianchi F; De Smaele E; Mesuraca M; Morrone G; Bond HM
Cell Death Dis; 2019 Sep; 10(10):715. PubMed ID: 31558698
[TBL] [Abstract][Full Text] [Related]
8. Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth.
Di Magno L; Manzi D; D'Amico D; Coni S; Macone A; Infante P; Di Marcotullio L; De Smaele E; Ferretti E; Screpanti I; Agostinelli E; Gulino A; Canettieri G
Cell Cycle; 2014; 13(21):3404-13. PubMed ID: 25485584
[TBL] [Abstract][Full Text] [Related]
9. Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1.
Götschel F; Berg D; Gruber W; Bender C; Eberl M; Friedel M; Sonntag J; Rüngeler E; Hache H; Wierling C; Nietfeld W; Lehrach H; Frischauf A; Schwartz-Albiez R; Aberger F; Korf U
PLoS One; 2013; 8(6):e65403. PubMed ID: 23762360
[TBL] [Abstract][Full Text] [Related]
10. Curcumin analogue BDDD-721 exhibits more potent anticancer effects than curcumin on medulloblastoma by targeting Shh/Gli1 signaling pathway.
Gong W; Zhao W; Liu G; Shi L; Zhao X
Aging (Albany NY); 2022 Jul; 14(13):5464-5477. PubMed ID: 35802536
[TBL] [Abstract][Full Text] [Related]
11. Identification of pseudolaric acid B as a novel Hedgehog pathway inhibitor in medulloblastoma.
Wei SF; He DH; Zhang SB; Lu Y; Ye X; Fan XZ; Wang H; Wang Q; Liu YQ
Biochem Pharmacol; 2021 Aug; 190():114593. PubMed ID: 33964282
[TBL] [Abstract][Full Text] [Related]
12. ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli.
Huang W; Liu H; Tan W; Wang J
Med Oncol; 2022 Sep; 39(12):188. PubMed ID: 36071246
[TBL] [Abstract][Full Text] [Related]
13. Cynanbungeigenin C and D, a pair of novel epimers from Cynanchum bungei, suppress hedgehog pathway-dependent medulloblastoma by blocking signaling at the level of Gli.
Li XY; Zhou LF; Gao LJ; Wei Y; Xu SF; Chen FY; Huang WJ; Tan WF; Ye YP
Cancer Lett; 2018 Apr; 420():195-207. PubMed ID: 29425683
[TBL] [Abstract][Full Text] [Related]
14. Prostaglandin E1 Inhibits
Wu F; Zhang C; Zhao C; Wu H; Teng Z; Jiang T; Wang Y
Cancer Res; 2020 Jul; 80(13):2818-2832. PubMed ID: 32371475
[TBL] [Abstract][Full Text] [Related]
15. GABA
Kaushik I; Srivastava SK
Mol Ther; 2022 Jul; 30(7):2584-2602. PubMed ID: 35331907
[TBL] [Abstract][Full Text] [Related]
16. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.
Long J; Li B; Rodriguez-Blanco J; Pastori C; Volmar CH; Wahlestedt C; Capobianco A; Bai F; Pei XH; Ayad NG; Robbins DJ
J Biol Chem; 2014 Dec; 289(51):35494-502. PubMed ID: 25355313
[TBL] [Abstract][Full Text] [Related]
17. RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism.
Azatyan A; Gallo-Oller G; Diao Y; Selivanova G; Johnsen JI; Zaphiropoulos PG
Cancer Lett; 2019 Feb; 442():341-350. PubMed ID: 30447254
[TBL] [Abstract][Full Text] [Related]
18. Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance.
Dijkgraaf GJ; Alicke B; Weinmann L; Januario T; West K; Modrusan Z; Burdick D; Goldsmith R; Robarge K; Sutherlin D; Scales SJ; Gould SE; Yauch RL; de Sauvage FJ
Cancer Res; 2011 Jan; 71(2):435-44. PubMed ID: 21123452
[TBL] [Abstract][Full Text] [Related]
19. β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.
Zinke J; Schneider FT; Harter PN; Thom S; Ziegler N; Toftgård R; Plate KH; Liebner S
Mol Cancer; 2015 Feb; 14(1):17. PubMed ID: 25645196
[TBL] [Abstract][Full Text] [Related]
20. mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.
Wu CC; Hou S; Orr BA; Kuo BR; Youn YH; Ong T; Roth F; Eberhart CG; Robinson GW; Solecki DJ; Taketo MM; Gilbertson RJ; Roussel MF; Han YG
Dev Cell; 2017 Dec; 43(6):673-688.e5. PubMed ID: 29103956
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
