135 related articles for article (PubMed ID: 35174659)
21. The role of CYP3A4 mRNA transcript with shortened 3'-untranslated region in hepatocyte differentiation, liver development, and response to drug induction.
Li D; Gaedigk R; Hart SN; Leeder JS; Zhong XB
Mol Pharmacol; 2012 Jan; 81(1):86-96. PubMed ID: 21998292
[TBL] [Abstract][Full Text] [Related]
22. The application of HepRG cells in evaluation of cytochrome P450 induction properties of drug compounds.
Andersson TB
Methods Mol Biol; 2010; 640():375-87. PubMed ID: 20645063
[TBL] [Abstract][Full Text] [Related]
23. Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo.
Henderson CJ; McLaughlin LA; Scheer N; Stanley LA; Wolf CR
Mol Pharmacol; 2015 Apr; 87(4):733-9. PubMed ID: 25657337
[TBL] [Abstract][Full Text] [Related]
24. Long-term functional stability of human HepaRG hepatocytes and use for chronic toxicity and genotoxicity studies.
Jossé R; Aninat C; Glaise D; Dumont J; Fessard V; Morel F; Poul JM; Guguen-Guillouzo C; Guillouzo A
Drug Metab Dispos; 2008 Jun; 36(6):1111-8. PubMed ID: 18347083
[TBL] [Abstract][Full Text] [Related]
25. Optimisation of the HepaRG cell line model for drug toxicity studies using two different cultivation conditions: advantages and limitations.
Hammour MM; Othman A; Aspera-Werz R; Braun B; Weis-Klemm M; Wagner S; Nadalin S; Histing T; Ruoß M; Nüssler AK
Arch Toxicol; 2022 Sep; 96(9):2511-2521. PubMed ID: 35748891
[TBL] [Abstract][Full Text] [Related]
26. Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Zanelli U; Caradonna NP; Hallifax D; Turlizzi E; Houston JB
Drug Metab Dispos; 2012 Jan; 40(1):104-10. PubMed ID: 21998403
[TBL] [Abstract][Full Text] [Related]
27. Drug metabolism of CYP3A4, CYP2C9 and CYP2D6 substrates in pigs and humans.
Thörn HA; Lundahl A; Schrickx JA; Dickinson PA; Lennernäs H
Eur J Pharm Sci; 2011 Jun; 43(3):89-98. PubMed ID: 21447389
[TBL] [Abstract][Full Text] [Related]
28. Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug.
Berger B; Bachmann F; Duthaler U; Krähenbühl S; Haschke M
Front Pharmacol; 2018; 9():774. PubMed ID: 30087611
[TBL] [Abstract][Full Text] [Related]
29. Cytochrome P450 expression and regulation in CYP3A4/CYP2D6 double transgenic humanized mice.
Felmlee MA; Lon HK; Gonzalez FJ; Yu AM
Drug Metab Dispos; 2008 Feb; 36(2):435-41. PubMed ID: 18048490
[TBL] [Abstract][Full Text] [Related]
30. Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells.
Ogasawara A; Kato N; Torimoto N; Aohara F; Ohashi R; Yamada Y; Taniguchi H
Drug Metab Lett; 2018; 12(1):14-23. PubMed ID: 29357810
[TBL] [Abstract][Full Text] [Related]
31. Evaluation of CYP3A4 inhibition and hepatotoxicity using DMSO-treated human hepatoma HuH-7 cells.
Liu Y; Flynn TJ; Xia M; Wiesenfeld PL; Ferguson MS
Cell Biol Toxicol; 2015 Oct; 31(4-5):221-30. PubMed ID: 26377104
[TBL] [Abstract][Full Text] [Related]
32. Development of a DsRed-expressing HepaRG cell line for real-time monitoring of hepatocyte-like cell differentiation by fluorescence imaging, with application in screening of novel geometric microstructured cell growth substrates.
Uta M; Sima LE; Hoffmann P; Dinca V; Branza-Nichita N
Biomed Microdevices; 2017 Mar; 19(1):3. PubMed ID: 28070697
[TBL] [Abstract][Full Text] [Related]
33. CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA).
Carmo H; Brulport M; Hermes M; Oesch F; de Boer D; Remião F; Carvalho F; Schön MR; Krebsfaenger N; Doehmer J; Bastos Mde L; Hengstler JG
Toxicology; 2007 Jan; 229(3):236-44. PubMed ID: 17156908
[TBL] [Abstract][Full Text] [Related]
34. Generation of cytochrome P450 enzyme-polymorphic human induced pluripotent stem cell lines with CYP2D6*10/CYP3A5*3C and CYP2D6*10/CYP2C19*2.
Lee J; Kim G; Chi KY; Han C; Kim JH
Stem Cell Res; 2022 Dec; 65():102970. PubMed ID: 36399926
[TBL] [Abstract][Full Text] [Related]
35. Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG cells.
McGinnity DF; Zhang G; Kenny JR; Hamilton GA; Otmani S; Stams KR; Haney S; Brassil P; Stresser DM; Riley RJ
Drug Metab Dispos; 2009 Jun; 37(6):1259-68. PubMed ID: 19307295
[TBL] [Abstract][Full Text] [Related]
36. Analysis of hiPSCs differentiation toward hepatocyte-like cells upon extended exposition to oncostatin.
Danoy M; Tauran Y; Poulain S; Arakawa H; Mori D; Araya K; Kato S; Kido T; Kusuhara H; Kato Y; Miyajima A; Plessy C; Sakai Y; Leclerc E
Differentiation; 2020; 114():36-48. PubMed ID: 32563741
[TBL] [Abstract][Full Text] [Related]
37. Influence of CYP2D6 and CYP3A4 Phenotypes, Drug Interactions, and Vitamin D Status on Tamoxifen Biotransformation.
Antunes MV; Timm TA; de Oliveira V; Staudt DE; Raymundo S; Gössling G; Biazús JV; Cavalheiro JA; Rosa DD; Wallemacq P; Haufroid V; Linden R; Schwartsmann G
Ther Drug Monit; 2015 Dec; 37(6):733-44. PubMed ID: 25853922
[TBL] [Abstract][Full Text] [Related]
38. Evaluation of organic anion-transporting polypeptide 1B1 and CYP3A4 activities in primary human hepatocytes and HepaRG cells cultured in a dynamic three-dimensional bioreactor system.
Ulvestad M; Darnell M; Molden E; Ellis E; Åsberg A; Andersson TB
J Pharmacol Exp Ther; 2012 Oct; 343(1):145-56. PubMed ID: 22789711
[TBL] [Abstract][Full Text] [Related]
39. Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG.
Rasmussen MK; Daujat-Chavanieu M; Gerbal-Chaloin S
Toxicol Lett; 2017 Aug; 277():1-8. PubMed ID: 28571685
[TBL] [Abstract][Full Text] [Related]
40. Quantitative Evaluation of Cytochrome P450 3A4 Inhibition and Hepatotoxicity in HepaRG 3-D Spheroids.
Shin DS; Seo H; Yang JY; Joo J; Im SH; Kim SS; Kim SK; Bae MA
Int J Toxicol; 2018; 37(5):393-403. PubMed ID: 29923436
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
