320 related articles for article (PubMed ID: 35178052)
1. Pharmacological Inhibition of FAK-Pyk2 Pathway Protects Against Organ Damage and Prolongs the Survival of Septic Mice.
Alves GF; Aimaretti E; Einaudi G; Mastrocola R; de Oliveira JG; Collotta D; Porchietto E; Aragno M; Cifani C; Sordi R; Thiemermann C; Fernandes D; Collino M
Front Immunol; 2022; 13():837180. PubMed ID: 35178052
[TBL] [Abstract][Full Text] [Related]
2. Delayed Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Inhibition by Trametinib Attenuates Systemic Inflammatory Responses and Multiple Organ Injury in Murine Sepsis.
Smith JA; Mayeux PR; Schnellmann RG
Crit Care Med; 2016 Aug; 44(8):e711-20. PubMed ID: 27031380
[TBL] [Abstract][Full Text] [Related]
3. FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammation.
Murphy JM; Jeong K; Rodriguez YAR; Kim JH; Ahn EE; Lim SS
Sci Rep; 2019 May; 9(1):7617. PubMed ID: 31110200
[TBL] [Abstract][Full Text] [Related]
4. ICOS-Fc as innovative immunomodulatory approach to counteract inflammation and organ injury in sepsis.
Alves GF; Stoppa I; Aimaretti E; Monge C; Mastrocola R; Porchietto E; Einaudi G; Collotta D; Bertocchi I; Boggio E; Gigliotti CL; Clemente N; Aragno M; Fernandes D; Cifani C; Thiemermann C; Dianzani C; Dianzani U; Collino M
Front Immunol; 2022; 13():992614. PubMed ID: 36119089
[TBL] [Abstract][Full Text] [Related]
5. Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness.
Behmoaram E; Bijian K; Jie S; Xu Y; Darnel A; Bismar TA; Alaoui-Jamali MA
Am J Pathol; 2008 Nov; 173(5):1540-50. PubMed ID: 18832579
[TBL] [Abstract][Full Text] [Related]
6. (R)-Ketamine ameliorates lethal inflammatory responses and multi-organ injury in mice induced by cecum ligation and puncture.
Zhang J; Ma L; Hashimoto Y; Wan X; Shan J; Qu Y; Hashimoto K
Life Sci; 2021 Nov; 284():119882. PubMed ID: 34384829
[TBL] [Abstract][Full Text] [Related]
7. Targeted inhibition of FAK, PYK2 and BCL-XL synergistically enhances apoptosis in ovarian clear cell carcinoma cell lines.
Yoon H; Choi YL; Song JY; Do I; Kang SY; Ko YH; Song S; Kim BG
PLoS One; 2014; 9(2):e88587. PubMed ID: 24523919
[TBL] [Abstract][Full Text] [Related]
8. Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice.
O'Riordan CE; Purvis GSD; Collotta D; Chiazza F; Wissuwa B; Al Zoubi S; Stiehler L; Martin L; Coldewey SM; Collino M; Thiemermann C
Front Immunol; 2019; 10():2129. PubMed ID: 31552054
[TBL] [Abstract][Full Text] [Related]
9. Cooperation between c-Met and focal adhesion kinase family members in medulloblastoma and implications for therapy.
Guessous F; Yang Y; Johnson E; Marcinkiewicz L; Smith M; Zhang Y; Kofman A; Schiff D; Christensen J; Abounader R
Mol Cancer Ther; 2012 Feb; 11(2):288-97. PubMed ID: 22188814
[TBL] [Abstract][Full Text] [Related]
10. Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation.
Boutahar N; Guignandon A; Vico L; Lafage-Proust MH
J Biol Chem; 2004 Jul; 279(29):30588-99. PubMed ID: 15096502
[TBL] [Abstract][Full Text] [Related]
11. [Effect of combination therapy with propofol and hydrogen-rich saline on organ damage and cytokines in a murine model of sepsis].
Hong Y; Chen H; Yu Y; Xie K
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue; 2017 Apr; 29(4):316-320. PubMed ID: 28420464
[TBL] [Abstract][Full Text] [Related]
12. Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity.
Fan H; Guan JL
J Biol Chem; 2011 May; 286(21):18573-82. PubMed ID: 21471206
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of IκB kinase reduces the multiple organ dysfunction caused by sepsis in the mouse.
Coldewey SM; Rogazzo M; Collino M; Patel NS; Thiemermann C
Dis Model Mech; 2013 Jul; 6(4):1031-42. PubMed ID: 23649820
[TBL] [Abstract][Full Text] [Related]
14. B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading.
Tse KW; Dang-Lawson M; Lee RL; Vong D; Bulic A; Buckbinder L; Gold MR
J Biol Chem; 2009 Aug; 284(34):22865-77. PubMed ID: 19561089
[TBL] [Abstract][Full Text] [Related]
15. Adenosine monophosphate-activated protein kinase activation protects against sepsis-induced organ injury and inflammation.
Escobar DA; Botero-Quintero AM; Kautza BC; Luciano J; Loughran P; Darwiche S; Rosengart MR; Zuckerbraun BS; Gomez H
J Surg Res; 2015 Mar; 194(1):262-72. PubMed ID: 25456115
[TBL] [Abstract][Full Text] [Related]
16. Involvement of proline-rich tyrosine kinase 2 in platelet activation: tyrosine phosphorylation mostly dependent on alphaIIbbeta3 integrin and protein kinase C, translocation to the cytoskeleton and association with Shc through Grb2.
Ohmori T; Yatomi Y; Asazuma N; Satoh K; Ozaki Y
Biochem J; 2000 Apr; 347(Pt 2):561-9. PubMed ID: 10749687
[TBL] [Abstract][Full Text] [Related]
17. Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis.
Chung IC; OuYang CN; Yuan SN; Li HP; Chen JT; Shieh HR; Chen YJ; Ojcius DM; Chu CL; Yu JS; Chang YS; Chen LC
Sci Rep; 2016 Oct; 6():36214. PubMed ID: 27796369
[TBL] [Abstract][Full Text] [Related]
18. Evolution of an immune suppressive macrophage phenotype as a product of P38 MAPK activation in polymicrobial sepsis.
Song GY; Chung CS; Jarrar D; Chaudry IH; Ayala A
Shock; 2001 Jan; 15(1):42-8. PubMed ID: 11198356
[TBL] [Abstract][Full Text] [Related]
19. Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant-induced migration, adhesion and Akt activation in follicular and marginal zone B cells.
Tse KW; Lin KB; Dang-Lawson M; Guzman-Perez A; Aspnes GE; Buckbinder L; Gold MR
Cell Immunol; 2012; 275(1-2):47-54. PubMed ID: 22507871
[TBL] [Abstract][Full Text] [Related]
20. (alpha)v(beta)3 integrins and Pyk2 mediate insulin-like growth factor I activation of Src and mitogen-activated protein kinase in 3T3-L1 cells.
Sekimoto H; Eipper-Mains J; Pond-Tor S; Boney CM
Mol Endocrinol; 2005 Jul; 19(7):1859-67. PubMed ID: 15761030
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
