166 related articles for article (PubMed ID: 35178174)
1. Design, Synthesis, and Biological Evaluation of Apcin-Based CDC20 Inhibitors.
Bhuniya R; Yuan X; Bai L; Howie KL; Wang R; Li W; Park F; Yang CY
ACS Med Chem Lett; 2022 Feb; 13(2):188-195. PubMed ID: 35178174
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological evaluation of CDC20 inhibitors for treatment of triple-negative breast cancer.
Zhao SF; Leng JF; Xie SS; Zhu LQ; Zhang MY; Kong LY; Yin Y
Eur J Med Chem; 2024 Mar; 268():116204. PubMed ID: 38364716
[TBL] [Abstract][Full Text] [Related]
3. Discovery of Ureido-Based Apcin Analogues as Cdc20-specific Inhibitors against Cancer.
He Y; Le X; Hu G; Li Q; Chen Z
Pharmaceuticals (Basel); 2023 Feb; 16(2):. PubMed ID: 37259447
[TBL] [Abstract][Full Text] [Related]
4. Cdc20 inhibitor apcin inhibits the growth and invasion of osteosarcoma cells.
Gao Y; Zhang B; Wang Y; Shang G
Oncol Rep; 2018 Aug; 40(2):841-848. PubMed ID: 29901174
[TBL] [Abstract][Full Text] [Related]
5. Paradoxical mitotic exit induced by a small molecule inhibitor of APC/C
Richeson KV; Bodrug T; Sackton KL; Yamaguchi M; Paulo JA; Gygi SP; Schulman BA; Brown NG; King RW
Nat Chem Biol; 2020 May; 16(5):546-555. PubMed ID: 32152539
[TBL] [Abstract][Full Text] [Related]
6. Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.
Sackton KL; Dimova N; Zeng X; Tian W; Zhang M; Sackton TB; Meaders J; Pfaff KL; Sigoillot F; Yu H; Luo X; King RW
Nature; 2014 Oct; 514(7524):646-9. PubMed ID: 25156254
[TBL] [Abstract][Full Text] [Related]
7. Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells.
Lub S; Maes A; Maes K; De Veirman K; De Bruyne E; Menu E; Fostier K; Kassambara A; Moreaux J; Hose D; Leleu X; King RW; Vanderkerken K; Van Valckenborgh E
Oncotarget; 2016 Jan; 7(4):4062-76. PubMed ID: 26716651
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of Cdc20 suppresses the metastasis in triple negative breast cancer (TNBC).
Song C; Lowe VJ; Lee S
Breast Cancer; 2021 Sep; 28(5):1073-1086. PubMed ID: 33813687
[TBL] [Abstract][Full Text] [Related]
9. CDC20: a novel therapeutic target in cancer.
He W; Meng J
Am J Transl Res; 2023; 15(2):678-693. PubMed ID: 36915766
[TBL] [Abstract][Full Text] [Related]
10. An in vitro assay for Cdc20-dependent mitotic anaphase-promoting complex activity from budding yeast.
Schuyler SC; Murray AW
Methods Mol Biol; 2009; 545():271-85. PubMed ID: 19475395
[TBL] [Abstract][Full Text] [Related]
11. p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Chen Y; Yang P; Wang J; Gao S; Xiao S; Zhang W; Zhu M; Wang Y; Ke X; Jing H
Exp Hematol Oncol; 2023 Mar; 12(1):28. PubMed ID: 36882855
[TBL] [Abstract][Full Text] [Related]
12. Cdc20 protein contains a destruction-box but, unlike Clb2, its proteolysisis not acutely dependent on the activity of anaphase-promoting complex.
Goh PY; Lim HH; Surana U
Eur J Biochem; 2000 Jan; 267(2):434-49. PubMed ID: 10632713
[TBL] [Abstract][Full Text] [Related]
13. Targeting Cdc20 as a novel cancer therapeutic strategy.
Wang L; Zhang J; Wan L; Zhou X; Wang Z; Wei W
Pharmacol Ther; 2015 Jul; 151():141-51. PubMed ID: 25850036
[TBL] [Abstract][Full Text] [Related]
14. Discovery of a Dual Tubulin Polymerization and Cell Division Cycle 20 Homologue Inhibitor via Structural Modification on Apcin.
Huang P; Le X; Huang F; Yang J; Yang H; Ma J; Hu G; Li Q; Chen Z
J Med Chem; 2020 May; 63(9):4685-4700. PubMed ID: 32290657
[TBL] [Abstract][Full Text] [Related]
15. Anaphase-promoting complex/cyclosome-Cdc-20 promotes Zwint-1 degradation.
He Y; Li R; Gu L; Deng H; Zhao Y; Guo Y; Yu S; Wang G
Cell Biochem Funct; 2020 Jun; 38(4):451-459. PubMed ID: 31945194
[TBL] [Abstract][Full Text] [Related]
16. TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1.
Vodermaier HC; Gieffers C; Maurer-Stroh S; Eisenhaber F; Peters JM
Curr Biol; 2003 Sep; 13(17):1459-68. PubMed ID: 12956947
[TBL] [Abstract][Full Text] [Related]
17. Apcin inhibits the growth and invasion of glioblastoma cells and improves glioma sensitivity to temozolomide.
Ding Y; Zhang C; He L; Song X; Zheng C; Pan Y; Yu S
Bioengineered; 2021 Dec; 12(2):10791-10798. PubMed ID: 34753395
[TBL] [Abstract][Full Text] [Related]
18. An old dog learns new tricks: a novel function for Cdc20-APC in dendrite morphogenesis in neurons.
Puram SV; Kim AH; Bonni A
Cell Cycle; 2010 Feb; 9(3):482-5. PubMed ID: 20195072
[TBL] [Abstract][Full Text] [Related]
19. Spindle assembly checkpoint protein Cdc20 transcriptionally activates expression of ubiquitin carrier protein UbcH10.
Nath S; Banerjee T; Sen D; Das T; Roychoudhury S
J Biol Chem; 2011 May; 286(18):15666-77. PubMed ID: 21454660
[TBL] [Abstract][Full Text] [Related]
20. Role of ubiquitylation of components of mitotic checkpoint complex in their dissociation from anaphase-promoting complex/cyclosome.
Sitry-Shevah D; Kaisari S; Teichner A; Miniowitz-Shemtov S; Hershko A
Proc Natl Acad Sci U S A; 2018 Feb; 115(8):1777-1782. PubMed ID: 29432156
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
