These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 35184041)

  • 1. Distinct Roles of the Sister Nuclear Receptors PXR and CAR in Liver Cancer Development.
    Yoshinari K; Shizu R
    Drug Metab Dispos; 2022 Jul; 50(7):1019-1026. PubMed ID: 35184041
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
    PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of Nuclear Receptors PXR and CAR in Xenobiotic-Induced Hepatocyte Proliferation and Chemical Carcinogenesis.
    Yoshinari K
    Biol Pharm Bull; 2019; 42(8):1243-1252. PubMed ID: 31366862
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
    Luisier R; Lempiäinen H; Scherbichler N; Braeuning A; Geissler M; Dubost V; Müller A; Scheer N; Chibout SD; Hara H; Picard F; Theil D; Couttet P; Vitobello A; Grenet O; Grasl-Kraupp B; Ellinger-Ziegelbauer H; Thomson JP; Meehan RR; Elcombe CR; Henderson CJ; Wolf CR; Schwarz M; Moulin P; Terranova R; Moggs JG
    Toxicol Sci; 2014 Jun; 139(2):501-11. PubMed ID: 24690595
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The xenobiotic receptors PXR and CAR in liver physiology, an update.
    Cai X; Young GM; Xie W
    Biochim Biophys Acta Mol Basis Dis; 2021 Jun; 1867(6):166101. PubMed ID: 33600998
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats.
    Haines C; Chatham LR; Vardy A; Elcombe CR; Foster JR; Lake BG
    Toxicology; 2018 May; 400-401():20-27. PubMed ID: 29548889
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The influence of the long-term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice.
    Shizu R; Ishimura M; Nobusawa S; Hosaka T; Sasaki T; Kakizaki S; Yoshinari K
    Arch Toxicol; 2021 Mar; 95(3):1089-1102. PubMed ID: 33398415
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
    J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phenobarbital in Nuclear Receptor Activation: An Update.
    Men S; Wang H
    Drug Metab Dispos; 2023 Feb; 51(2):210-218. PubMed ID: 36351837
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
    Kast HR; Goodwin B; Tarr PT; Jones SA; Anisfeld AM; Stoltz CM; Tontonoz P; Kliewer S; Willson TM; Edwards PA
    J Biol Chem; 2002 Jan; 277(4):2908-15. PubMed ID: 11706036
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of Hepatic Long Noncoding RNAs by Pregnane X Receptor and Constitutive Androstane Receptor Agonists in Mouse Liver.
    Dempsey JL; Cui JY
    Drug Metab Dispos; 2019 Mar; 47(3):329-339. PubMed ID: 30593543
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional Interaction between Pregnane X Receptor and Yes-Associated Protein in Xenobiotic-Dependent Liver Hypertrophy and Drug Metabolism.
    Abe T; Shizu R; Sasaki T; Shimizu Y; Hosaka T; Kodama S; Matsuzawa A; Yoshinari K
    J Pharmacol Exp Ther; 2019 Dec; 371(3):590-601. PubMed ID: 31533970
    [TBL] [Abstract][Full Text] [Related]  

  • 13. AhR, PXR and CAR: From Xenobiotic Receptors to Metabolic Sensors.
    Rakateli L; Huchzermeier R; van der Vorst EPC
    Cells; 2023 Nov; 12(23):. PubMed ID: 38067179
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
    Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
    Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator.
    Elcombe CR; Peffer RC; Wolf DC; Bailey J; Bars R; Bell D; Cattley RC; Ferguson SS; Geter D; Goetz A; Goodman JI; Hester S; Jacobs A; Omiecinski CJ; Schoeny R; Xie W; Lake BG
    Crit Rev Toxicol; 2014 Jan; 44(1):64-82. PubMed ID: 24180433
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.
    Tolson AH; Wang H
    Adv Drug Deliv Rev; 2010 Oct; 62(13):1238-49. PubMed ID: 20727377
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Xenosensors CAR and PXR at work: impact on statin metabolism.
    Marino M; di Masi A; Trezza V; Pallottini V; Polticelli F; Ascenzi P
    Curr Drug Metab; 2011 Mar; 12(3):300-11. PubMed ID: 21395534
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.
    Tamasi V; Juvan P; Beer M; Rozman D; Meyer UA
    Mol Pharm; 2009; 6(5):1573-81. PubMed ID: 19708687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of Nuclear Receptors PXR and CAR by Small Molecules and Signal Crosstalk: Roles in Drug Metabolism and Beyond.
    Poudel S; Huber AD; Chen T
    Drug Metab Dispos; 2023 Feb; 51(2):228-236. PubMed ID: 36116789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genetic polymorphisms in the TATA box and upstream phenobarbital-responsive enhancer module of the UGT1A1 promoter have combined effects on UDP-glucuronosyltransferase 1A1 transcription mediated by constitutive androstane receptor, pregnane X receptor, or glucocorticoid receptor in human liver.
    Li Y; Buckley D; Wang S; Klaassen CD; Zhong XB
    Drug Metab Dispos; 2009 Sep; 37(9):1978-86. PubMed ID: 19541828
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.