BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 35190724)

  • 1. Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting.
    Salomon R; Rotem H; Katzenelenbogen Y; Weiner A; Cohen Saban N; Feferman T; Amit I; Dahan R
    Nat Cancer; 2022 Mar; 3(3):287-302. PubMed ID: 35190724
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bispecific antibodies targeting CD40 and tumor-associated antigens promote cross-priming of T cells resulting in an antitumor response superior to monospecific antibodies.
    Hägerbrand K; Varas L; Deronic A; Nyesiga B; Sundstedt A; Ljung L; Sakellariou C; Werchau D; Thagesson M; Gomez Jimenez D; Greiff L; Celander M; Smedenfors K; Rosén A; Bölükbas D; Carlsson F; Levin M; Säll A; von Schantz L; Lindstedt M; Ellmark P
    J Immunother Cancer; 2022 Nov; 10(11):. PubMed ID: 36323431
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phase I study of ABBV-428, a mesothelin-CD40 bispecific, in patients with advanced solid tumors.
    Luke JJ; Barlesi F; Chung K; Tolcher AW; Kelly K; Hollebecque A; Le Tourneau C; Subbiah V; Tsai F; Kao S; Cassier PA; Khasraw M; Kindler HL; Fang H; Fan F; Allaire K; Patel M; Ye S; Chao DT; Henner WR; Hayflick JS; McDevitt MA; Fong L
    J Immunother Cancer; 2021 Feb; 9(2):. PubMed ID: 33608377
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Bispecific Molecule Targeting CD40 and Tumor Antigen Mesothelin Enhances Tumor-Specific Immunity.
    Ye S; Cohen D; Belmar NA; Choi D; Tan SS; Sho M; Akamatsu Y; Kim H; Iyer R; Cabel J; Lake M; Song D; Harlan J; Zhang C; Fang Y; Wahl AF; Culp P; Hollenbaugh D; Chao DT
    Cancer Immunol Res; 2019 Nov; 7(11):1864-1875. PubMed ID: 31462409
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Next Generation CD40 Agonistic Antibodies for Cancer Immunotherapy.
    Salomon R; Dahan R
    Front Immunol; 2022; 13():940674. PubMed ID: 35911742
    [TBL] [Abstract][Full Text] [Related]  

  • 6. XFab-α4-1BB/CD40L fusion protein activates dendritic cells, improves expansion of antigen-specific T cells, and exhibits antitumour efficacy in multiple solid tumour models.
    Wang B; Liu Y; Yuan R; Dou X; Qian N; Pan X; Xu G; Xu Q; Dong B; Yang C; Li H; Wang J; Bai G; Liu L; Gao X
    Cancer Immunol Immunother; 2023 Dec; 72(12):4015-4030. PubMed ID: 37863852
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CD40- and 41BB-specific antibody fusion proteins with PDL1 blockade-restricted agonism.
    Medler J; Kucka K; Melo V; Zhang T; von Rotenhan S; Ulrich J; Bremer E; Hudecek M; Beilhack A; Wajant H
    Theranostics; 2022; 12(4):1486-1499. PubMed ID: 35198053
    [No Abstract]   [Full Text] [Related]  

  • 8. DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
    Muik A; Adams 3rd HC; Gieseke F; Altintas I; Schoedel KB; Blum JM; Sänger B; Burm SM; Stanganello E; Verzijl D; Spires VM; Vascotto F; Toker A; Quinkhardt J; Fereshteh M; Diken M; Satijn DPE; Kreiter S; Ahmadi T; Breij ECW; Türeci Ö; Sasser K; Sahin U; Jure-Kunkel M
    J Immunother Cancer; 2022 Jun; 10(6):. PubMed ID: 35688554
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rationale and clinical development of CD40 agonistic antibodies for cancer immunotherapy.
    Enell Smith K; Deronic A; Hägerbrand K; Norlén P; Ellmark P
    Expert Opin Biol Ther; 2021 Dec; 21(12):1635-1646. PubMed ID: 34043482
    [No Abstract]   [Full Text] [Related]  

  • 10. A potential novel cancer immunotherapy: Agonistic anti-CD40 antibodies.
    Jian CZ; Lin L; Hsu CL; Chen YH; Hsu C; Tan CT; Ou DL
    Drug Discov Today; 2024 Mar; 29(3):103893. PubMed ID: 38272173
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Bispecific Antibody Antagonizes Prosurvival CD40 Signaling and Promotes Vγ9Vδ2 T cell-Mediated Antitumor Responses in Human B-cell Malignancies.
    de Weerdt I; Lameris R; Scheffer GL; Vree J; de Boer R; Stam AG; van de Ven R; Levin MD; Pals ST; Roovers RC; Parren PWHI; de Gruijl TD; Kater AP; van der Vliet HJ
    Cancer Immunol Res; 2021 Jan; 9(1):50-61. PubMed ID: 33177109
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity.
    Sum E; Rapp M; Fröbel P; Le Clech M; Dürr H; Giusti AM; Perro M; Speziale D; Kunz L; Menietti E; Brünker P; Hopfer U; Lechmann M; Sobieniecki A; Appelt B; Adelfio R; Nicolini V; Freimoser-Grundschober A; Jordaan W; Labiano S; Weber F; Emrich T; Christen F; Essig B; Romero P; Trumpfheller C; Umaña P
    Clin Cancer Res; 2021 Jul; 27(14):4036-4053. PubMed ID: 33771854
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines.
    Ceglia V; Zurawski S; Montes M; Kroll M; Bouteau A; Wang Z; Ellis J; Igyártó BZ; Lévy Y; Zurawski G
    Front Immunol; 2021; 12():786144. PubMed ID: 35095862
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A PDGFRB- and CD40-targeting bispecific AffiMab induces stroma-targeted immune cell activation.
    Mega A; Mebrahtu A; Aniander G; Ryer E; Sköld A; Sandegren A; Backström Rydin E; Rockberg J; Östman A; Frejd FY
    MAbs; 2023; 15(1):2223750. PubMed ID: 37332119
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Agonistic CD40 antibodies and cancer therapy.
    Vonderheide RH; Glennie MJ
    Clin Cancer Res; 2013 Mar; 19(5):1035-43. PubMed ID: 23460534
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Concomitant or delayed anti-TNF differentially impact on immune-related adverse events and antitumor efficacy after anti-CD40 therapy.
    Jacoberger-Foissac C; Blake SJ; Liu J; McDonald E; Triscott H; Nakamura K; Smyth MJ; Teng MW
    J Immunother Cancer; 2020 Nov; 8(2):. PubMed ID: 33199513
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IL-15 synergizes with CD40 agonist antibodies to induce durable immunity against bladder cancer.
    Wong JL; Smith P; Angulo-Lozano J; Ranti D; Bochner BH; Sfakianos JP; Horowitz A; Ravetch JV; Knorr DA
    Proc Natl Acad Sci U S A; 2023 Aug; 120(35):e2306782120. PubMed ID: 37607227
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity.
    Knorr DA; Dahan R; Ravetch JV
    Proc Natl Acad Sci U S A; 2018 Oct; 115(43):11048-11053. PubMed ID: 30297432
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity.
    Ishihara J; Ishihara A; Potin L; Hosseinchi P; Fukunaga K; Damo M; Gajewski TF; Swartz MA; Hubbell JA
    Mol Cancer Ther; 2018 Nov; 17(11):2399-2411. PubMed ID: 30097487
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Harnessing the potential of CD40 agonism in cancer therapy.
    Zhou Y; Richmond A; Yan C
    Cytokine Growth Factor Rev; 2024 Feb; 75():40-56. PubMed ID: 38102001
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.