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5. Tankyrase Sterile α Motif Domain Polymerization Is Required for Its Role in Wnt Signaling. Riccio AA; McCauley M; Langelier MF; Pascal JM Structure; 2016 Sep; 24(9):1573-81. PubMed ID: 27499439 [TBL] [Abstract][Full Text] [Related]
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7. Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Koirala S; Klein J; Zheng Y; Glenn NO; Eisemann T; Fon Tacer K; Miller DJ; Kulak O; Lu M; Finkelstein DB; Neale G; Tillman H; Vogel P; Strand DW; Lum L; Brautigam CA; Pascal JM; Clements WK; Potts PR Cell Rep; 2020 Jul; 32(3):107922. PubMed ID: 32698014 [TBL] [Abstract][Full Text] [Related]
9. Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling. Callow MG; Tran H; Phu L; Lau T; Lee J; Sandoval WN; Liu PS; Bheddah S; Tao J; Lill JR; Hongo JA; Davis D; Kirkpatrick DS; Polakis P; Costa M PLoS One; 2011; 6(7):e22595. PubMed ID: 21799911 [TBL] [Abstract][Full Text] [Related]
10. Tankyrase Inhibition Attenuates Cardiac Dilatation and Dysfunction in Ischemic Heart Failure. Wang H; Segersvärd H; Siren J; Perttunen S; Immonen K; Kosonen R; Chen YC; Tolva J; Laivuori M; Mäyränpää MI; Kovanen PT; Sinisalo J; Laine M; Tikkanen I; Lakkisto P Int J Mol Sci; 2022 Sep; 23(17):. PubMed ID: 36077457 [TBL] [Abstract][Full Text] [Related]
11. Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes. Thorvaldsen TE; Pedersen NM; Wenzel EM; Schultz SW; Brech A; Liestøl K; Waaler J; Krauss S; Stenmark H Mol Cancer Res; 2015 Nov; 13(11):1487-501. PubMed ID: 26124443 [TBL] [Abstract][Full Text] [Related]
12. Structural insights into SAM domain-mediated tankyrase oligomerization. DaRosa PA; Ovchinnikov S; Xu W; Klevit RE Protein Sci; 2016 Sep; 25(9):1744-52. PubMed ID: 27328430 [TBL] [Abstract][Full Text] [Related]
13. Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors. Shirai F; Tsumura T; Yashiroda Y; Yuki H; Niwa H; Sato S; Chikada T; Koda Y; Washizuka K; Yoshimoto N; Abe M; Onuki T; Mazaki Y; Hirama C; Fukami T; Watanabe H; Honma T; Umehara T; Shirouzu M; Okue M; Kano Y; Watanabe T; Kitamura K; Shitara E; Muramatsu Y; Yoshida H; Mizutani A; Seimiya H; Yoshida M; Koyama H J Med Chem; 2019 Apr; 62(7):3407-3427. PubMed ID: 30883102 [TBL] [Abstract][Full Text] [Related]
14. Evidence for tankyrases as antineoplastic targets in lung cancer. Busch AM; Johnson KC; Stan RV; Sanglikar A; Ahmed Y; Dmitrovsky E; Freemantle SJ BMC Cancer; 2013 Apr; 13():211. PubMed ID: 23621985 [TBL] [Abstract][Full Text] [Related]
15. A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice. Waaler J; Machon O; Tumova L; Dinh H; Korinek V; Wilson SR; Paulsen JE; Pedersen NM; Eide TJ; Machonova O; Gradl D; Voronkov A; von Kries JP; Krauss S Cancer Res; 2012 Jun; 72(11):2822-32. PubMed ID: 22440753 [TBL] [Abstract][Full Text] [Related]
16. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth. Lau T; Chan E; Callow M; Waaler J; Boggs J; Blake RA; Magnuson S; Sambrone A; Schutten M; Firestein R; Machon O; Korinek V; Choo E; Diaz D; Merchant M; Polakis P; Holsworth DD; Krauss S; Costa M Cancer Res; 2013 May; 73(10):3132-44. PubMed ID: 23539443 [TBL] [Abstract][Full Text] [Related]
17. The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2. Croy HE; Fuller CN; Giannotti J; Robinson P; Foley AVA; Yamulla RJ; Cosgriff S; Greaves BD; von Kleeck RA; An HH; Powers CM; Tran JK; Tocker AM; Jacob KD; Davis BK; Roberts DM J Biol Chem; 2016 Jun; 291(24):12747-12760. PubMed ID: 27068743 [TBL] [Abstract][Full Text] [Related]
18. RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model. Mizutani A; Yashiroda Y; Muramatsu Y; Yoshida H; Chikada T; Tsumura T; Okue M; Shirai F; Fukami T; Yoshida M; Seimiya H Cancer Sci; 2018 Dec; 109(12):4003-4014. PubMed ID: 30238564 [TBL] [Abstract][Full Text] [Related]
19. The Discovery and Characterization of K-756, a Novel Wnt/β-Catenin Pathway Inhibitor Targeting Tankyrase. Okada-Iwasaki R; Takahashi Y; Watanabe Y; Ishida H; Saito J; Nakai R; Asai A Mol Cancer Ther; 2016 Jul; 15(7):1525-34. PubMed ID: 27196752 [TBL] [Abstract][Full Text] [Related]
20. Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors. Hua Z; Bregman H; Buchanan JL; Chakka N; Guzman-Perez A; Gunaydin H; Huang X; Gu Y; Berry V; Liu J; Teffera Y; Huang L; Egge B; Emkey R; Mullady EL; Schneider S; Andrews PS; Acquaviva L; Dovey J; Mishra A; Newcomb J; Saffran D; Serafino R; Strathdee CA; Turci SM; Stanton M; Wilson C; Dimauro EF J Med Chem; 2013 Dec; 56(24):10003-15. PubMed ID: 24294969 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]