BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 35195438)

  • 1. Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens.
    Mullowney MW; Maltseva NI; Endres M; Kim Y; Joachimiak A; Crofts TS
    Microbiol Spectr; 2022 Apr; 10(2):e0013922. PubMed ID: 35195438
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and Characterization of a Nitroreductase Capable of Conferring Bacterial Resistance to Chloramphenicol.
    Crofts TS; Sontha P; King AO; Wang B; Biddy BA; Zanolli N; Gaumnitz J; Dantas G
    Cell Chem Biol; 2019 Apr; 26(4):559-570.e6. PubMed ID: 30799223
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues.
    Hall KR; Robins KJ; Williams EM; Rich MH; Calcott MJ; Copp JN; Little RF; Schwörer R; Evans GB; Patrick WM; Ackerley DF
    Elife; 2020 Nov; 9():. PubMed ID: 33185191
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chloramphenicol is a substrate for a novel nitroreductase pathway in Haemophilus influenzae.
    Smith AL; Erwin AL; Kline T; Unrath WC; Nelson K; Weber A; Howald WN
    Antimicrob Agents Chemother; 2007 Aug; 51(8):2820-9. PubMed ID: 17526758
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Study of the role played by NfsA, NfsB nitroreductase and NemA flavin reductase from Escherichia coli in the conversion of ethyl 2-(2'-nitrophenoxy)acetate to 4-hydroxy-(2H)-1,4-benzoxazin-3(4H)-one (D-DIBOA), a benzohydroxamic acid with interesting biological properties.
    Valle A; Le Borgne S; Bolívar J; Cabrera G; Cantero D
    Appl Microbiol Biotechnol; 2012 Apr; 94(1):163-71. PubMed ID: 22173483
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxygen-insensitive nitroreductases NfsA and NfsB of Escherichia coli function under anaerobic conditions as lawsone-dependent Azo reductases.
    Rau J; Stolz A
    Appl Environ Microbiol; 2003 Jun; 69(6):3448-55. PubMed ID: 12788749
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characteristics of major Escherichia coli reductases involved in aerobic nitro and azo reduction.
    Mercier C; Chalansonnet V; Orenga S; Gilbert C
    J Appl Microbiol; 2013 Oct; 115(4):1012-22. PubMed ID: 23795903
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Investigating the promiscuity of the chloramphenicol nitroreductase from Haemophilus influenzae towards the reduction of 4-nitrobenzene derivatives.
    Green KD; Fosso MY; Mayhoub AS; Garneau-Tsodikova S
    Bioorg Med Chem Lett; 2019 May; 29(9):1127-1132. PubMed ID: 30826292
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oxygen-insensitive nitroreductases: analysis of the roles of nfsA and nfsB in development of resistance to 5-nitrofuran derivatives in Escherichia coli.
    Whiteway J; Koziarz P; Veall J; Sandhu N; Kumar P; Hoecher B; Lambert IB
    J Bacteriol; 1998 Nov; 180(21):5529-39. PubMed ID: 9791100
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gene cloning, purification, and characterization of NfsB, a minor oxygen-insensitive nitroreductase from Escherichia coli, similar in biochemical properties to FRase I, the major flavin reductase in Vibrio fischeri.
    Zenno S; Koike H; Tanokura M; Saigo K
    J Biochem; 1996 Oct; 120(4):736-44. PubMed ID: 8947835
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Engineering
    Williams EM; Rich MH; Mowday AM; Ashoorzadeh A; Copp JN; Guise CP; Anderson RF; Flanagan JU; Smaill JB; Patterson AV; Ackerley DF
    Biochemistry; 2019 Sep; 58(35):3700-3710. PubMed ID: 31403283
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conversion of NfsB, a minor Escherichia coli nitroreductase, to a flavin reductase similar in biochemical properties to FRase I, the major flavin reductase in Vibrio fischeri, by a single amino acid substitution.
    Zenno S; Koike H; Tanokura M; Saigo K
    J Bacteriol; 1996 Aug; 178(15):4731-3. PubMed ID: 8755909
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of Escherichia coli nitroreductase NfsB in the metabolism of nitrobenzodiazepines.
    Linwu SW; Syu CJ; Chen YL; Wang AH; Peng FC
    Biochem Pharmacol; 2009 Jul; 78(1):96-103. PubMed ID: 19447228
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Use of nfsB, encoding nitroreductase, as a reporter gene to determine the mutational spectrum of spontaneous mutations in Neisseria gonorrhoeae.
    Stein DC; Carrizosa E; Dunham S
    BMC Microbiol; 2009 Nov; 9():239. PubMed ID: 19930647
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxygen-insensitive nitroreductase E. coli NfsA, but not NfsB, is inhibited by fumarate.
    Day MA; Jarrom D; Rajah N; Searle PF; Hyde EI; White SA
    Proteins; 2023 May; 91(5):585-592. PubMed ID: 36443029
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Steady-state and stopped-flow kinetic studies of three Escherichia coli NfsB mutants with enhanced activity for the prodrug CB1954.
    Jarrom D; Jaberipour M; Guise CP; Daff S; White SA; Searle PF; Hyde EI
    Biochemistry; 2009 Aug; 48(32):7665-72. PubMed ID: 19580253
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel 5-Nitrofuran-Activating Reductase in Escherichia coli.
    Le VVH; Davies IG; Moon CD; Wheeler D; Biggs PJ; Rakonjac J
    Antimicrob Agents Chemother; 2019 Nov; 63(11):. PubMed ID: 31481448
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery and evaluation of Escherichia coli nitroreductases that activate the anti-cancer prodrug CB1954.
    Prosser GA; Copp JN; Syddall SP; Williams EM; Smaill JB; Wilson WR; Patterson AV; Ackerley DF
    Biochem Pharmacol; 2010 Mar; 79(5):678-87. PubMed ID: 19852945
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of the nitroreductase NfsB in an E. coli strain as a whole-cell biocatalyst for the production of chlorinated analogues of the natural herbicide DIBOA.
    de la Calle ME; Cabrera G; Cantero D; Valle A; Bolivar J
    N Biotechnol; 2019 May; 50():9-19. PubMed ID: 30630092
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pseudomonas aeruginosa NfsB and nitro-CBI-DEI--a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy.
    Green LK; Syddall SP; Carlin KM; Bell GD; Guise CP; Mowday AM; Hay MP; Smaill JB; Patterson AV; Ackerley DF
    Mol Cancer; 2013 Jun; 12():58. PubMed ID: 23758947
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.