BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 35210421)

  • 1. Tuning the rate of aggregation of hIAPP into amyloid using small-molecule modulators of assembly.
    Xu Y; Maya-Martinez R; Guthertz N; Heath GR; Manfield IW; Breeze AL; Sobott F; Foster R; Radford SE
    Nat Commun; 2022 Feb; 13(1):1040. PubMed ID: 35210421
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aggregation of an amyloidogenic fragment of human islet amyloid polypeptide.
    Rhoades E; Agarwal J; Gafni A
    Biochim Biophys Acta; 2000 Feb; 1476(2):230-8. PubMed ID: 10669788
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular Dynamics Simulations Reveal the Inhibitory Mechanism of Dopamine against Human Islet Amyloid Polypeptide (hIAPP) Aggregation and Its Destabilization Effect on hIAPP Protofibrils.
    Lao Z; Chen Y; Tang Y; Wei G
    ACS Chem Neurosci; 2019 Sep; 10(9):4151-4159. PubMed ID: 31436406
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
    Meier DT; Entrup L; Templin AT; Hogan MF; Mellati M; Zraika S; Hull RL; Kahn SE
    Diabetologia; 2016 Oct; 59(10):2166-71. PubMed ID: 27393137
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Studies on the cross-interaction between hIAPP and Aβ
    Pang B; Zhuang X; Bian X; Liu S; Liu Z; Song F
    J Mass Spectrom; 2020 Oct; 55(10):e4643. PubMed ID: 32893436
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular Structure, Membrane Interactions, and Toxicity of the Islet Amyloid Polypeptide in Type 2 Diabetes Mellitus.
    Caillon L; Hoffmann AR; Botz A; Khemtemourian L
    J Diabetes Res; 2016; 2016():5639875. PubMed ID: 26636105
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular insights into the oligomerization dynamics and conformations of amyloidogenic and non-amyloidogenic amylin from discrete molecular dynamics simulations.
    Wang Y; Liu Y; Zhang Y; Wei G; Ding F; Sun Y
    Phys Chem Chem Phys; 2022 Sep; 24(36):21773-21785. PubMed ID: 36098068
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The glucagon-like peptide-1 receptor agonist exenatide restores impaired pro-islet amyloid polypeptide processing in cultured human islets: implications in type 2 diabetes and islet transplantation.
    Park YJ; Ao Z; Kieffer TJ; Chen H; Safikhan N; Thompson DM; Meloche M; Warnock GL; Marzban L
    Diabetologia; 2013 Mar; 56(3):508-19. PubMed ID: 23262664
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alpha1-antitrypsin ameliorates islet amyloid-induced glucose intolerance and β-cell dysfunction.
    Rodríguez-Comas J; Moreno-Vedia J; Obach M; Castaño C; de Pablo S; Alcarraz-Vizán G; Díaz-Catalán D; Mestre A; Horrillo R; Costa M; Novials A; Servitja JM
    Mol Metab; 2020 Jul; 37():100984. PubMed ID: 32229246
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Azadirachtin inhibits amyloid formation, disaggregates pre-formed fibrils and protects pancreatic β-cells from human islet amyloid polypeptide/amylin-induced cytotoxicity.
    Dubey R; Patil K; Dantu SC; Sardesai DM; Bhatia P; Malik N; Acharya JD; Sarkar S; Ghosh S; Chakrabarti R; Sharma S; Kumar A
    Biochem J; 2019 Mar; 476(5):889-907. PubMed ID: 30814273
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genistein: A Dual Inhibitor of Both Amyloid β and Human Islet Amylin Peptides.
    Ren B; Liu Y; Zhang Y; Cai Y; Gong X; Chang Y; Xu L; Zheng J
    ACS Chem Neurosci; 2018 May; 9(5):1215-1224. PubMed ID: 29432676
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of hIAPP Amyloid Aggregation and Pancreatic β-Cell Toxicity by OH-Terminated PAMAM Dendrimer.
    Gurzov EN; Wang B; Pilkington EH; Chen P; Kakinen A; Stanley WJ; Litwak SA; Hanssen EG; Davis TP; Ding F; Ke PC
    Small; 2016 Mar; 12(12):1615-26. PubMed ID: 26808649
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An investigation into the potential action of polyphenols against human Islet Amyloid Polypeptide aggregation in type 2 diabetes.
    Mahboob A; Senevirathne DKL; Paul P; Nabi F; Khan RH; Chaari A
    Int J Biol Macromol; 2023 Jan; 225():318-350. PubMed ID: 36400215
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cross-seeding enables repurposing of aurein antimicrobial peptides as a promoter of human islet amyloid polypeptide (hIAPP).
    Tang Y; Zhang D; Gong X; Zheng J
    J Mater Chem B; 2023 Aug; 11(33):7920-7932. PubMed ID: 37431688
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide.
    de Koning EJ; Morris ER; Hofhuis FM; Posthuma G; Höppener JW; Morris JF; Capel PJ; Clark A; Verbeek JS
    Proc Natl Acad Sci U S A; 1994 Aug; 91(18):8467-71. PubMed ID: 8078905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Melatonin Inhibits hIAPP Oligomerization by Preventing β-Sheet and Hydrogen Bond Formation of the Amyloidogenic Region Revealed by Replica-Exchange Molecular Dynamics Simulation.
    Wang G; Zhu X; Song X; Zhang Q; Qian Z
    Int J Mol Sci; 2022 Sep; 23(18):. PubMed ID: 36142176
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hydrophobic/Hydrophilic Ratio of Amphiphilic Helix Mimetics Determines the Effects on Islet Amyloid Polypeptide Aggregation.
    Tang H; Sun Y; Ding F
    J Chem Inf Model; 2022 Apr; 62(7):1760-1770. PubMed ID: 35311274
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human IAPP amyloidogenic properties and pancreatic β-cell death.
    Fernández MS
    Cell Calcium; 2014 Nov; 56(5):416-27. PubMed ID: 25224501
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of the Role of the Conserved Disulfide in Amyloid Formation by Human Islet Amyloid Polypeptide in Homogeneous and Heterogeneous Environments.
    Ridgway Z; Zhang X; Wong AG; Abedini A; Schmidt AM; Raleigh DP
    Biochemistry; 2018 May; 57(21):3065-3074. PubMed ID: 29697253
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human islet amyloid polypeptide (hIAPP) aggregation in type 2 diabetes: Correlation between intrinsic physicochemical properties of hIAPP aggregates and their cytotoxicity.
    Chaari A; Ladjimi M
    Int J Biol Macromol; 2019 Sep; 136():57-65. PubMed ID: 31195047
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.