182 related articles for article (PubMed ID: 35212811)
1. The role of SHMT2 in modulating lipid metabolism in hepatocytes via glycine-mediated mTOR activation.
Choi YJ; Lee G; Yun SH; Lee W; Yu J; Kim SK; Lee BH
Amino Acids; 2022 May; 54(5):823-834. PubMed ID: 35212811
[TBL] [Abstract][Full Text] [Related]
2. SHMT2 Promotes Liver Regeneration Through Glycine-activated Akt/mTOR Pathway.
Wang M; Yuan F; Bai H; Zhang J; Wu H; Zheng K; Zhang W; Miao M; Gong J
Transplantation; 2019 Jul; 103(7):e188-e197. PubMed ID: 30964837
[TBL] [Abstract][Full Text] [Related]
3. Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma.
Woo CC; Chen WC; Teo XQ; Radda GK; Lee PT
Oncotarget; 2016 Aug; 7(33):53005-53017. PubMed ID: 27391339
[TBL] [Abstract][Full Text] [Related]
4. Cancer proteome and metabolite changes linked to SHMT2.
Tong J; Krieger JR; Taylor P; Bagshaw R; Kang J; Jeedigunta S; Wybenga-Groot LE; Zhang W; Badr H; Mirhadi S; Pham NA; Coyaud É; Yu M; Li M; Cabanero M; Raught B; Maynes JT; Hawkins C; Tsao MS; Moran MF
PLoS One; 2020; 15(9):e0237981. PubMed ID: 32903271
[TBL] [Abstract][Full Text] [Related]
5. SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells.
Zhang Y; Liu Z; Wang X; Jian H; Xiao H; Wen T
Cancer Gene Ther; 2022 Oct; 29(10):1514-1527. PubMed ID: 35422087
[TBL] [Abstract][Full Text] [Related]
6. SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT.
Huo FC; Xie M; Zhu ZM; Zheng JN; Pei DS
Genomics; 2022 Jul; 114(4):110424. PubMed ID: 35798250
[TBL] [Abstract][Full Text] [Related]
7. Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway.
Li Z; Xu G; Qin Y; Zhang C; Tang H; Yin Y; Xiang X; Li Y; Zhao J; Mulholland M; Zhang W
Proc Natl Acad Sci U S A; 2014 Sep; 111(36):13163-8. PubMed ID: 25157160
[TBL] [Abstract][Full Text] [Related]
8. [Serine hydroxymethyl transferase 2 regulates the AMPK/mTOR pathway and induces autophagy to promote chemotherapy resistance in colon cancer cells].
Liu F; Liu Y; Gao H; Wang L
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2019 Apr; 35(4):344-350; 356. PubMed ID: 31167694
[TBL] [Abstract][Full Text] [Related]
9. Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastoma.
Clark RA; Qiao J; Jacobson JC; Chung DH
Oncotarget; 2022; 13():32-45. PubMed ID: 35018218
[TBL] [Abstract][Full Text] [Related]
10. Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs.
Minton DR; Nam M; McLaughlin DJ; Shin J; Bayraktar EC; Alvarez SW; Sviderskiy VO; Papagiannakopoulos T; Sabatini DM; Birsoy K; Possemato R
Mol Cell; 2018 Feb; 69(4):610-621.e5. PubMed ID: 29452640
[TBL] [Abstract][Full Text] [Related]
11. Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties.
Tramonti A; Nardella C; di Salvo ML; Barile A; Cutruzzolà F; Contestabile R
Biochemistry; 2018 Dec; 57(51):6984-6996. PubMed ID: 30500180
[TBL] [Abstract][Full Text] [Related]
12. SHMT2 reduces fatty liver but is necessary for liver inflammation and fibrosis in mice.
Chen G; Zhou G; Zhai L; Bao X; Tiwari N; Li J; Mottillo E; Wang J
Commun Biol; 2024 Feb; 7(1):173. PubMed ID: 38347107
[TBL] [Abstract][Full Text] [Related]
13. SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke AC; Doebele C; Zindel A; Lee KS; Rieke SA; Ceribelli M; Comoglio F; Phelan JD; Wang JQ; Pikman Y; Jahn D; Häupl B; Schneider C; Scheich S; Tosto FA; Bohnenberger H; Stauder P; Schnütgen F; Slabicki M; Coulibaly ZA; Wolf S; Bojarczuk K; Chapuy B; Brandts CH; Stroebel P; Lewis CA; Engelke M; Xu X; Kim H; Dang TH; Schmitz R; Hodson DJ; Stegmaier K; Urlaub H; Serve H; Schmitt CA; Kreuz F; Knittel G; Rabinowitz JD; Reinhardt HC; Vander Heiden MG; Thomas C; Staudt LM; Zenz T; Oellerich T
Blood; 2022 Jan; 139(4):538-553. PubMed ID: 34624079
[TBL] [Abstract][Full Text] [Related]
14. Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Liu Z; Fan M; Hou J; Pan S; Xu Y; Zhang H; Liu C; Hao X; Li X; Wang H
Cell Death Dis; 2023 Feb; 14(2):144. PubMed ID: 36806313
[TBL] [Abstract][Full Text] [Related]
15. Vital role of SHMT2 in diverse disease.
Ma W; Liu R; Zhao K; Zhong J
Biochem Biophys Res Commun; 2023 Sep; 671():160-165. PubMed ID: 37302290
[TBL] [Abstract][Full Text] [Related]
16. Glycine homeostasis requires reverse SHMT flux.
McBride MJ; Hunter CJ; Zhang Z; TeSlaa T; Xu X; Ducker GS; Rabinowitz JD
Cell Metab; 2024 Jan; 36(1):103-115.e4. PubMed ID: 38171330
[TBL] [Abstract][Full Text] [Related]
17. Cytoplasmic SHMT2 drives the progression and metastasis of colorectal cancer by inhibiting β-catenin degradation.
Liu C; Wang L; Liu X; Tan Y; Tao L; Xiao Y; Deng P; Wang H; Deng Q; Lin Y; Jie H; Zhang H; Zhang J; Peng Y; Zhang H; Zhou Z; Sun Q; Cen X; Zhao Y
Theranostics; 2021; 11(6):2966-2986. PubMed ID: 33456583
[No Abstract] [Full Text] [Related]
18. Regulation of lipid-induced macrophage polarization through modulating peroxisome proliferator-activated receptor-gamma activity affects hepatic lipid metabolism via a Toll-like receptor 4/NF-κB signaling pathway.
Wu HM; Ni XX; Xu QY; Wang Q; Li XY; Hua J
J Gastroenterol Hepatol; 2020 Nov; 35(11):1998-2008. PubMed ID: 32128893
[TBL] [Abstract][Full Text] [Related]
19. ERRα activates SHMT2 transcription to enhance the resistance of breast cancer to lapatinib via modulating the mitochondrial metabolic adaption.
Li X; Zhang K; Hu Y; Luo N
Biosci Rep; 2020 Jan; 40(1):. PubMed ID: 31894856
[TBL] [Abstract][Full Text] [Related]
20. Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD.
Ghrayeb A; Finney AC; Agranovich B; Peled D; Anand SK; McKinney MP; Sarji M; Yang D; Weissman N; Drucker S; Fernandes SI; Fernández-García J; Mahan K; Abassi Z; Tan L; Lorenzi PL; Traylor J; Zhang J; Abramovich I; Chen YE; Rom O; Mor I; Gottlieb E
Cell Metab; 2024 Jan; 36(1):116-129.e7. PubMed ID: 38171331
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]