These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 35213030)

  • 1. Intrathecal Delivery of Therapeutic Oligonucleotides for Potent Modulation of Gene Expression in the Central Nervous System.
    Kennedy Z; Gilbert JW; Godinho BMDC
    Methods Mol Biol; 2022; 2434():345-353. PubMed ID: 35213030
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A physiologically-based pharmacokinetic model to describe antisense oligonucleotide distribution after intrathecal administration.
    Monine M; Norris D; Wang Y; Nestorov I
    J Pharmacokinet Pharmacodyn; 2021 Oct; 48(5):639-654. PubMed ID: 33991294
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intrathecal Delivery of Antisense Oligonucleotides in the Rat Central Nervous System.
    Chen Y; Mazur C; Luo Y; Sun L; Zhang M; McCampbell A; Tomassy GS
    J Vis Exp; 2019 Oct; (152):. PubMed ID: 31736489
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Direct Administration and Gene Modulation Using Antisense Oligonucleotides Within the CNS.
    Wahlestedt C; Khorkova O
    Cell Mol Neurobiol; 2021 Jul; 41(5):849-853. PubMed ID: 32656646
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Convective forces increase rostral delivery of intrathecal radiotracers and antisense oligonucleotides in the cynomolgus monkey nervous system.
    Sullivan JM; Mazur C; Wolf DA; Horky L; Currier N; Fitzsimmons B; Hesterman J; Pauplis R; Haller S; Powers B; Tayefeh L; DeBrosse-Serra B; Hoppin J; Kordasiewicz H; Swayze EE; Verma A
    J Transl Med; 2020 Aug; 18(1):309. PubMed ID: 32771027
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of a simple, rapid, and robust intrathecal catheterization method in the rat.
    Mazur C; Fitzsimmons B; Kamme F; Nichols B; Powers B; Wancewicz E
    J Neurosci Methods; 2017 Mar; 280():36-46. PubMed ID: 28163066
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biodistribution of Radioactively Labeled Splice Modulating Antisense Oligonucleotides After Intracerebroventricular and Intrathecal Injection in Mice.
    Metz T; Welling MM; Suidgeest E; Nieuwenhuize E; de Vlaam T; Curtis D; Hailu TT; van der Weerd L; van Roon-Mom WMC
    Nucleic Acid Ther; 2024 Feb; 34(1):26-34. PubMed ID: 38386285
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS.
    Nagata T; Dwyer CA; Yoshida-Tanaka K; Ihara K; Ohyagi M; Kaburagi H; Miyata H; Ebihara S; Yoshioka K; Ishii T; Miyata K; Miyata K; Powers B; Igari T; Yamamoto S; Arimura N; Hirabayashi H; Uchihara T; Hara RI; Wada T; Bennett CF; Seth PP; Rigo F; Yokota T
    Nat Biotechnol; 2021 Dec; 39(12):1529-1536. PubMed ID: 34385691
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lentiviral gene delivery to CNS by spinal intrathecal administration to neonatal mice.
    Fedorova E; Battini L; Prakash-Cheng A; Marras D; Gusella GL
    J Gene Med; 2006 Apr; 8(4):414-24. PubMed ID: 16389638
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Toxicologic Pathology Forum: Opinion on Interpretive Challenges for Procedure-Related Effects Associated With Direct Central Nervous System Delivery of Oligonucleotides to Rodents, Dogs, and Nonhuman Primates.
    Berman-Booty LD; Klein SK; Mazur C; Schroeder J; Korte S; Ludwig FT; Romeike A; Bolon B; Grieves JL
    Toxicol Pathol; 2023 Aug; 51(6):375-389. PubMed ID: 38179962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides.
    Geary RS; Norris D; Yu R; Bennett CF
    Adv Drug Deliv Rev; 2015 Jun; 87():46-51. PubMed ID: 25666165
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS.
    Kandasamy P; Liu Y; Aduda V; Akare S; Alam R; Andreucci A; Boulay D; Bowman K; Byrne M; Cannon M; Chivatakarn O; Shelke JD; Iwamoto N; Kawamoto T; Kumarasamy J; Lamore S; Lemaitre M; Lin X; Longo K; Looby R; Marappan S; Metterville J; Mohapatra S; Newman B; Paik IH; Patil S; Purcell-Estabrook E; Shimizu M; Shum P; Standley S; Taborn K; Tripathi S; Yang H; Yin Y; Zhao X; Dale E; Vargeese C
    Nucleic Acids Res; 2022 Jun; 50(10):5401-5423. PubMed ID: 35106589
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A mechanistic pharmacokinetic model for intrathecal administration of antisense oligonucleotides.
    Linninger AA; Barua D; Hang Y; Iadevaia S; Vakilynejad M
    Front Physiol; 2023; 14():1130925. PubMed ID: 37334053
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Range of Neurological Signs in Cynomolgus Monkeys After Intrathecal Bolus Administration of Antisense Oligonucleotides.
    Korte S; Runge F; Wozniak MM; Ludwig FT; Smieja D; Korytko P; Mecklenburg L
    Int J Toxicol; 2020; 39(6):505-509. PubMed ID: 32794413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Highly efficient gene silencing in mouse brain by overhanging-duplex oligonucleotides via intraventricular route.
    Lei Mon SS; Yoshioka K; Jia C; Kunieda T; Asami Y; Yoshida-Tanaka K; Piao W; Kuwahara H; Nishina K; Nagata T; Yokota T
    FEBS Lett; 2020 May; 594(9):1413-1423. PubMed ID: 31990989
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nusinersen: antisense oligonucleotide to increase SMN protein production in spinal muscular atrophy.
    Paton DM
    Drugs Today (Barc); 2017 Jun; 53(6):327-337. PubMed ID: 28799578
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intrathecal Injection of Newborn Mouse for Genome Editing and Drug Delivery.
    Lu X; Jiang YH
    J Vis Exp; 2024 Mar; (205):. PubMed ID: 38526075
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neurotrophin-3 antisense oligonucleotide attenuates nerve injury-induced Abeta-fibre sprouting.
    White DM
    Brain Res; 2000 Dec; 885(1):79-86. PubMed ID: 11121532
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modification of phosphorothioate oligonucleotides yields potent analogs with minimal toxicity for antisense experiments in the CNS.
    Peng Ho S; Livanov V; Zhang W; Li J; Lesher T
    Brain Res Mol Brain Res; 1998 Nov; 62(1):1-11. PubMed ID: 9795101
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Delivery of Antisense Oligonucleotides to the Mouse Brain by Intracerebroventricular Injections.
    Metz T; Kuijper EC; van Roon-Mom WMC
    Methods Mol Biol; 2022; 2434():333-341. PubMed ID: 35213029
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.