BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

683 related articles for article (PubMed ID: 35216965)

  • 1. Stromal HIF2 Regulates Immune Suppression in the Pancreatic Cancer Microenvironment.
    Garcia Garcia CJ; Huang Y; Fuentes NR; Turner MC; Monberg ME; Lin D; Nguyen ND; Fujimoto TN; Zhao J; Lee JJ; Bernard V; Yu M; Delahoussaye AM; Jimenez Sacarello I; Caggiano EG; Phan JL; Deorukhkar A; Molkentine JM; Saur D; Maitra A; Taniguchi CM
    Gastroenterology; 2022 Jun; 162(7):2018-2031. PubMed ID: 35216965
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combined MEK and STAT3 Inhibition Uncovers Stromal Plasticity by Enriching for Cancer-Associated Fibroblasts With Mesenchymal Stem Cell-Like Features to Overcome Immunotherapy Resistance in Pancreatic Cancer.
    Datta J; Dai X; Bianchi A; De Castro Silva I; Mehra S; Garrido VT; Lamichhane P; Singh SP; Zhou Z; Dosch AR; Messaggio F; Ban Y; Umland O; Hosein PJ; Nagathihalli NS; Merchant NB
    Gastroenterology; 2022 Dec; 163(6):1593-1612. PubMed ID: 35948109
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cancer-Associated Fibroblast Induces Acinar-to-Ductal Cell Transdifferentiation and Pancreatic Cancer Initiation Via LAMA5/ITGA4 Axis.
    Parte S; Kaur AB; Nimmakayala RK; Ogunleye AO; Chirravuri R; Vengoji R; Leon F; Nallasamy P; Rauth S; Alsafwani ZW; Lele S; Cox JL; Bhat I; Singh S; Batra SK; Ponnusamy MP
    Gastroenterology; 2024 May; 166(5):842-858.e5. PubMed ID: 38154529
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inter- and intra-tumoural heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma.
    Neuzillet C; Tijeras-Raballand A; Ragulan C; Cros J; Patil Y; Martinet M; Erkan M; Kleeff J; Wilson J; Apte M; Tosolini M; Wilson AS; Delvecchio FR; Bousquet C; Paradis V; Hammel P; Sadanandam A; Kocher HM
    J Pathol; 2019 May; 248(1):51-65. PubMed ID: 30575030
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition.
    Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA;
    Cancer Res; 2021 Jul; 81(13):3461-3479. PubMed ID: 33980655
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer.
    McAndrews KM; Chen Y; Darpolor JK; Zheng X; Yang S; Carstens JL; Li B; Wang H; Miyake T; Correa de Sampaio P; Kirtley ML; Natale M; Wu CC; Sugimoto H; LeBleu VS; Kalluri R
    Cancer Discov; 2022 Jun; 12(6):1580-1597. PubMed ID: 35348629
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential.
    Knudsen ES; Balaji U; Freinkman E; McCue P; Witkiewicz AK
    Oncotarget; 2016 Nov; 7(48):78396-78411. PubMed ID: 27623078
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer.
    Zhang Y; Ware MB; Zaidi MY; Ruggieri AN; Olson BM; Komar H; Farren MR; Nagaraju GP; Zhang C; Chen Z; Sarmiento JM; Ahmed R; Maithel SK; El-Rayes BF; Lesinski GB
    Mol Cancer Ther; 2021 Jan; 20(1):150-160. PubMed ID: 33037138
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Periostin- and podoplanin-positive cancer-associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma.
    Neuzillet C; Nicolle R; Raffenne J; Tijeras-Raballand A; Brunel A; Astorgues-Xerri L; Vacher S; Arbateraz F; Fanjul M; Hilmi M; Samain R; Klein C; Perraud A; Rebours V; Mathonnet M; Bièche I; Kocher H; Cros J; Bousquet C
    J Pathol; 2022 Dec; 258(4):408-425. PubMed ID: 36102377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia Potentiates the Inflammatory Fibroblast Phenotype Promoted by Pancreatic Cancer Cell-Derived Cytokines.
    Schwörer S; Cimino FV; Ros M; Tsanov KM; Ng C; Lowe SW; Carmona-Fontaine C; Thompson CB
    Cancer Res; 2023 May; 83(10):1596-1610. PubMed ID: 36912618
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting Aggressive Fibroblasts to Enhance the Treatment of Pancreatic Cancer.
    Yu Y; Schuck K; Friess H; Kong B
    Expert Opin Ther Targets; 2021 Jan; 25(1):5-13. PubMed ID: 33246383
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Tango between Cancer-Associated Fibroblasts (CAFs) and Immune Cells in Affecting Immunotherapy Efficacy in Pancreatic Cancer.
    Stouten I; van Montfoort N; Hawinkels LJAC
    Int J Mol Sci; 2023 May; 24(10):. PubMed ID: 37240052
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Opportunities and delusions regarding drug delivery targeting pancreatic cancer-associated fibroblasts.
    Liu H; Shi Y; Qian F
    Adv Drug Deliv Rev; 2021 May; 172():37-51. PubMed ID: 33705881
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CXCR2 signaling promotes secretory cancer-associated fibroblasts in pancreatic ductal adenocarcinoma.
    Awaji M; Saxena S; Wu L; Prajapati DR; Purohit A; Varney ML; Kumar S; Rachagani S; Ly QP; Jain M; Batra SK; Singh RK
    FASEB J; 2020 Jul; 34(7):9405-9418. PubMed ID: 32453916
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Syk Inhibition Reprograms Tumor-Associated Macrophages and Overcomes Gemcitabine-Induced Immunosuppression in Pancreatic Ductal Adenocarcinoma.
    Rohila D; Park IH; Pham TV; Weitz J; Hurtado de Mendoza T; Madheswaran S; Ishfaq M; Beaman C; Tapia E; Sun S; Patel J; Tamayo P; Lowy AM; Joshi S
    Cancer Res; 2023 Aug; 83(16):2675-2689. PubMed ID: 37306759
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis.
    Mizutani Y; Kobayashi H; Iida T; Asai N; Masamune A; Hara A; Esaki N; Ushida K; Mii S; Shiraki Y; Ando K; Weng L; Ishihara S; Ponik SM; Conklin MW; Haga H; Nagasaka A; Miyata T; Matsuyama M; Kobayashi T; Fujii T; Yamada S; Yamaguchi J; Wang T; Woods SL; Worthley D; Shimamura T; Fujishiro M; Hirooka Y; Enomoto A; Takahashi M
    Cancer Res; 2019 Oct; 79(20):5367-5381. PubMed ID: 31439548
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
    Graziano V; Dannhorn A; Hulme H; Williamson K; Buckley H; Karim SA; Wilson M; Lee SY; Kaistha BP; Islam S; Thaventhiran JED; Richards FM; Goodwin R; Brais R; Morton JP; Dovedi SJ; Schuller AG; Eyles J; Jodrell DI
    J Immunother Cancer; 2023 Aug; 11(8):. PubMed ID: 37553182
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cancer-associated fibroblasts promote M2 polarization of macrophages in pancreatic ductal adenocarcinoma.
    Zhang A; Qian Y; Ye Z; Chen H; Xie H; Zhou L; Shen Y; Zheng S
    Cancer Med; 2017 Feb; 6(2):463-470. PubMed ID: 28097809
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer.
    Kitamura F; Semba T; Yasuda-Yoshihara N; Yamada K; Nishimura A; Yamasaki J; Nagano O; Yasuda T; Yonemura A; Tong Y; Wang H; Akiyama T; Matsumura K; Uemura N; Itoyama R; Bu L; Fu L; Hu X; Wei F; Mima K; Imai K; Hayashi H; Yamashita YI; Miyamoto Y; Baba H; Ishimoto T
    JCI Insight; 2023 Oct; 8(20):. PubMed ID: 37733442
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer.
    Perez-Penco M; Weis-Banke SE; Schina A; Siersbæk M; Hübbe ML; Jørgensen MA; Lecoq I; Lara de la Torre L; Bendtsen SK; Martinenaite E; Holmström MO; Madsen DH; Donia M; Ødum N; Grøntved L; Andersen MH
    J Immunother Cancer; 2022 Dec; 10(12):. PubMed ID: 36600556
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.