254 related articles for article (PubMed ID: 35217144)
1. The role of lysosomal cathepsins in neurodegeneration: Mechanistic insights, diagnostic potential and therapeutic approaches.
Drobny A; Prieto Huarcaya S; Dobert J; Kluge A; Bunk J; Schlothauer T; Zunke F
Biochim Biophys Acta Mol Cell Res; 2022 Jul; 1869(7):119243. PubMed ID: 35217144
[TBL] [Abstract][Full Text] [Related]
2. Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.
McGlinchey RP; Lee JC
Proc Natl Acad Sci U S A; 2015 Jul; 112(30):9322-7. PubMed ID: 26170293
[TBL] [Abstract][Full Text] [Related]
3. Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.
Prieto Huarcaya S; Drobny A; Marques ARA; Di Spiezio A; Dobert JP; Balta D; Werner C; Rizo T; Gallwitz L; Bub S; Stojkovska I; Belur NR; Fogh J; Mazzulli JR; Xiang W; Fulzele A; Dejung M; Sauer M; Winner B; Rose-John S; Arnold P; Saftig P; Zunke F
Autophagy; 2022 May; 18(5):1127-1151. PubMed ID: 35287553
[TBL] [Abstract][Full Text] [Related]
4. Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models.
Drobny A; Boros FA; Balta D; Prieto Huarcaya S; Caylioglu D; Qazi N; Vandrey J; Schneider Y; Dobert JP; Pitcairn C; Mazzulli JR; Zunke F
Transl Neurodegener; 2023 Jun; 12(1):31. PubMed ID: 37312133
[TBL] [Abstract][Full Text] [Related]
5. Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes.
Wong CO
Int J Mol Sci; 2020 Jul; 21(14):. PubMed ID: 32708198
[TBL] [Abstract][Full Text] [Related]
6. Comparison of cathepsin protease activities in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease.
Mantle D; Falkous G; Ishiura S; Perry RH; Perry EK
J Neurol Sci; 1995 Jul; 131(1):65-70. PubMed ID: 7561949
[TBL] [Abstract][Full Text] [Related]
7. Lysosomal cathepsins and their regulation in aging and neurodegeneration.
Stoka V; Turk V; Turk B
Ageing Res Rev; 2016 Dec; 32():22-37. PubMed ID: 27125852
[TBL] [Abstract][Full Text] [Related]
8. The vicious cycle between α-synuclein aggregation and autophagic-lysosomal dysfunction.
Bellomo G; Paciotti S; Gatticchi L; Parnetti L
Mov Disord; 2020 Jan; 35(1):34-44. PubMed ID: 31729779
[TBL] [Abstract][Full Text] [Related]
9. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.
Mazzulli JR; Zunke F; Tsunemi T; Toker NJ; Jeon S; Burbulla LF; Patnaik S; Sidransky E; Marugan JJ; Sue CM; Krainc D
J Neurosci; 2016 Jul; 36(29):7693-706. PubMed ID: 27445146
[TBL] [Abstract][Full Text] [Related]
10. Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates.
Bae EJ; Yang NY; Lee C; Kim S; Lee HJ; Lee SJ
Cell Death Dis; 2015 Oct; 6(10):e1901. PubMed ID: 26448324
[TBL] [Abstract][Full Text] [Related]
11. TRPMLs and TPCs: Targets for lysosomal storage and neurodegenerative disease therapy?
Krogsaeter E; Rosato AS; Grimm C
Cell Calcium; 2022 May; 103():102553. PubMed ID: 35144097
[TBL] [Abstract][Full Text] [Related]
12. Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis.
Marques ARA; Di Spiezio A; Thießen N; Schmidt L; Grötzinger J; Lüllmann-Rauch R; Damme M; Storck SE; Pietrzik CU; Fogh J; Bär J; Mikhaylova M; Glatzel M; Bassal M; Bartsch U; Saftig P
Autophagy; 2020 May; 16(5):811-825. PubMed ID: 31282275
[TBL] [Abstract][Full Text] [Related]
13. Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins.
Cermak S; Kosicek M; Mladenovic-Djordjevic A; Smiljanic K; Kanazir S; Hecimovic S
PLoS One; 2016; 11(11):e0167428. PubMed ID: 27902765
[TBL] [Abstract][Full Text] [Related]
14. Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.
Bunk J; Prieto Huarcaya S; Drobny A; Dobert JP; Walther L; Rose-John S; Arnold P; Zunke F
Front Cell Dev Biol; 2021; 9():581805. PubMed ID: 33681191
[TBL] [Abstract][Full Text] [Related]
15. Cellular depletion of major cathepsin proteases reveals their concerted activities for lysosomal proteolysis.
Gallwitz L; Bleibaum F; Voss M; Schweizer M; Spengler K; Winter D; Zöphel F; Müller S; Lichtenthaler S; Damme M; Saftig P
Cell Mol Life Sci; 2024 May; 81(1):227. PubMed ID: 38775843
[TBL] [Abstract][Full Text] [Related]
16. Brain Disorders Due to Lysosomal Dysfunction.
Fraldi A; Klein AD; Medina DL; Settembre C
Annu Rev Neurosci; 2016 Jul; 39():277-95. PubMed ID: 27090953
[TBL] [Abstract][Full Text] [Related]
17. The Emerging Role of the Lysosome in Parkinson's Disease.
Navarro-Romero A; Montpeyó M; Martinez-Vicente M
Cells; 2020 Nov; 9(11):. PubMed ID: 33147750
[TBL] [Abstract][Full Text] [Related]
18. Immunotherapeutic Approaches for the Treatment of Neurodegenerative Diseases: Challenges and Outcomes.
Sushma ; Mondal AC
CNS Neurol Disord Drug Targets; 2023; 22(3):404-416. PubMed ID: 34963438
[TBL] [Abstract][Full Text] [Related]
19. The neuropathogenic contributions of lysosomal dysfunction.
Bahr BA; Bendiske J
J Neurochem; 2002 Nov; 83(3):481-9. PubMed ID: 12390510
[TBL] [Abstract][Full Text] [Related]
20. Preserving Lysosomal Function in the Aging Brain: Insights from Neurodegeneration.
Peng W; Minakaki G; Nguyen M; Krainc D
Neurotherapeutics; 2019 Jul; 16(3):611-634. PubMed ID: 31183763
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
