239 related articles for article (PubMed ID: 35217664)
1. A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Schmidt JM; Yang R; Kumar A; Hunker O; Seebacher J; Bleichert F
Nat Commun; 2022 Feb; 13(1):1059. PubMed ID: 35217664
[TBL] [Abstract][Full Text] [Related]
2. Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing.
Amasino AL; Gupta S; Friedman LJ; Gelles J; Bell SP
Proc Natl Acad Sci U S A; 2023 Jul; 120(29):e2221484120. PubMed ID: 37428921
[TBL] [Abstract][Full Text] [Related]
3. Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Yuan Z; Schneider S; Dodd T; Riera A; Bai L; Yan C; Magdalou I; Ivanov I; Stillman B; Li H; Speck C
Proc Natl Acad Sci U S A; 2020 Jul; 117(30):17747-17756. PubMed ID: 32669428
[TBL] [Abstract][Full Text] [Related]
4. CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6.
Chen S; Bell SP
Genes Dev; 2011 Feb; 25(4):363-72. PubMed ID: 21289063
[TBL] [Abstract][Full Text] [Related]
5. An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.
Fernández-Cid A; Riera A; Tognetti S; Herrera MC; Samel S; Evrin C; Winkler C; Gardenal E; Uhle S; Speck C
Mol Cell; 2013 May; 50(4):577-88. PubMed ID: 23603117
[TBL] [Abstract][Full Text] [Related]
6. The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Feng X; Noguchi Y; Barbon M; Stillman B; Speck C; Li H
Nat Commun; 2021 Jun; 12(1):3883. PubMed ID: 34162887
[TBL] [Abstract][Full Text] [Related]
7. Replication origin-flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence.
Warner MD; Azmi IF; Kang S; Zhao Y; Bell SP
J Biol Chem; 2017 Dec; 292(52):21417-21430. PubMed ID: 29074622
[TBL] [Abstract][Full Text] [Related]
8. Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase.
Randell JC; Bowers JL; Rodríguez HK; Bell SP
Mol Cell; 2006 Jan; 21(1):29-39. PubMed ID: 16387651
[TBL] [Abstract][Full Text] [Related]
9. Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases.
Takara TJ; Bell SP
EMBO J; 2011 Nov; 30(24):4885-96. PubMed ID: 22045335
[TBL] [Abstract][Full Text] [Related]
10. Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Schmidt JM; Bleichert F
Nat Commun; 2020 Aug; 11(1):4263. PubMed ID: 32848132
[TBL] [Abstract][Full Text] [Related]
11. Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
Yuan Z; Riera A; Bai L; Sun J; Nandi S; Spanos C; Chen ZA; Barbon M; Rappsilber J; Stillman B; Speck C; Li H
Nat Struct Mol Biol; 2017 Mar; 24(3):316-324. PubMed ID: 28191893
[TBL] [Abstract][Full Text] [Related]
12. A helicase-tethered ORC flip enables bidirectional helicase loading.
Gupta S; Friedman LJ; Gelles J; Bell SP
Elife; 2021 Dec; 10():. PubMed ID: 34882090
[TBL] [Abstract][Full Text] [Related]
13. The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.
Evrin C; Fernández-Cid A; Riera A; Zech J; Clarke P; Herrera MC; Tognetti S; Lurz R; Speck C
Nucleic Acids Res; 2014 Feb; 42(4):2257-69. PubMed ID: 24234446
[TBL] [Abstract][Full Text] [Related]
14. Changing protein-DNA interactions promote ORC binding-site exchange during replication origin licensing.
Zhang A; Friedman LJ; Gelles J; Bell SP
Proc Natl Acad Sci U S A; 2023 Jul; 120(30):e2305556120. PubMed ID: 37463200
[TBL] [Abstract][Full Text] [Related]
15. In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.
Evrin C; Fernández-Cid A; Zech J; Herrera MC; Riera A; Clarke P; Brill S; Lurz R; Speck C
Nucleic Acids Res; 2013 Mar; 41(5):3162-72. PubMed ID: 23376927
[TBL] [Abstract][Full Text] [Related]
16. Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading.
Chen S; de Vries MA; Bell SP
Genes Dev; 2007 Nov; 21(22):2897-907. PubMed ID: 18006685
[TBL] [Abstract][Full Text] [Related]
17. Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.
Sun J; Evrin C; Samel SA; Fernández-Cid A; Riera A; Kawakami H; Stillman B; Speck C; Li H
Nat Struct Mol Biol; 2013 Aug; 20(8):944-51. PubMed ID: 23851460
[TBL] [Abstract][Full Text] [Related]
18. ATPase-dependent quality control of DNA replication origin licensing.
Frigola J; Remus D; Mehanna A; Diffley JF
Nature; 2013 Mar; 495(7441):339-43. PubMed ID: 23474987
[TBL] [Abstract][Full Text] [Related]
19. Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
Remus D; Beuron F; Tolun G; Griffith JD; Morris EP; Diffley JF
Cell; 2009 Nov; 139(4):719-30. PubMed ID: 19896182
[TBL] [Abstract][Full Text] [Related]
20. DNA replication origins retain mobile licensing proteins.
Sánchez H; McCluskey K; van Laar T; van Veen E; Asscher FM; Solano B; Diffley JFX; Dekker NH
Nat Commun; 2021 Mar; 12(1):1908. PubMed ID: 33772005
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]