These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 35219626)

  • 21. The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity.
    Tomaszowski KH; Aasland D; Margison GP; Williams E; Pinder SI; Modesti M; Fuchs RP; Kaina B
    DNA Repair (Amst); 2015 Apr; 28():14-20. PubMed ID: 25703834
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.
    Ma W; Westmoreland JW; Gordenin DA; Resnick MA
    PLoS Genet; 2011 Apr; 7(4):e1002059. PubMed ID: 21552545
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth).
    Ramos AA; Pedro DF; Lima CF; Collins AR; Pereira-Wilson C
    Free Radic Biol Med; 2013 Jul; 60():41-8. PubMed ID: 23391575
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Dual repair modulation reverses Temozolomide resistance in vitro.
    Barvaux VA; Ranson M; Brown R; McElhinney RS; McMurry TB; Margison GP
    Mol Cancer Ther; 2004 Feb; 3(2):123-7. PubMed ID: 14985452
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Combined effect of temozolomide and hyperthermia on human melanoma cell growth and O6-methylguanine-DNA methyltransferase activity.
    Pagani E; Falcinelli S; Pepponi R; Turriziani M; Caporaso P; Caporali S; Bonmassar E; D'Atri S
    Int J Oncol; 2007 Feb; 30(2):443-51. PubMed ID: 17203227
    [TBL] [Abstract][Full Text] [Related]  

  • 26. O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo.
    Klapacz J; Meira LB; Luchetti DG; Calvo JA; Bronson RT; Edelmann W; Samson LD
    Proc Natl Acad Sci U S A; 2009 Jan; 106(2):576-81. PubMed ID: 19124772
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Nucleosomes suppress the formation of double-strand DNA breaks during attempted base excision repair of clustered oxidative damages.
    Cannan WJ; Tsang BP; Wallace SS; Pederson DS
    J Biol Chem; 2014 Jul; 289(29):19881-93. PubMed ID: 24891506
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Implication of localization of human DNA repair enzyme O6-methylguanine-DNA methyltransferase at active transcription sites in transcription-repair coupling of the mutagenic O6-methylguanine lesion.
    Ali RB; Teo AK; Oh HK; Chuang LS; Ayi TC; Li BF
    Mol Cell Biol; 1998 Mar; 18(3):1660-9. PubMed ID: 9488483
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.
    Naumann SC; Roos WP; Jöst E; Belohlavek C; Lennerz V; Schmidt CW; Christmann M; Kaina B
    Br J Cancer; 2009 Jan; 100(2):322-33. PubMed ID: 19127257
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.
    Groth P; Ausländer S; Majumder MM; Schultz N; Johansson F; Petermann E; Helleday T
    J Mol Biol; 2010 Sep; 402(1):70-82. PubMed ID: 20643142
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Deficient expression of O(6)-methylguanine-DNA methyltransferase combined with mismatch-repair proteins hMLH1 and hMSH2 is related to poor prognosis in human biliary tract carcinoma.
    Kohya N; Miyazaki K; Matsukura S; Yakushiji H; Kitajima Y; Kitahara K; Fukuhara M; Nakabeppu Y; Sekiguchi M
    Ann Surg Oncol; 2002 May; 9(4):371-9. PubMed ID: 11986189
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models.
    Kaina B; Ziouta A; Ochs K; Coquerelle T
    Mutat Res; 1997 Nov; 381(2):227-41. PubMed ID: 9434879
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damage.
    Teo AK; Oh HK; Ali RB; Li BF
    Mol Cell Biol; 2001 Oct; 21(20):7105-14. PubMed ID: 11564893
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents.
    Christmann M; Kaina B
    J Biol Chem; 2000 Nov; 275(46):36256-62. PubMed ID: 10954713
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O(6)-methylguanine due to high E2F1 regulated mismatch repair.
    Roos WP; Christmann M; Fraser ST; Kaina B
    Cell Death Differ; 2007 Aug; 14(8):1422-32. PubMed ID: 17464330
    [TBL] [Abstract][Full Text] [Related]  

  • 36. DNA repair in eukaryotes.
    Wood RD
    Annu Rev Biochem; 1996; 65():135-67. PubMed ID: 8811177
    [TBL] [Abstract][Full Text] [Related]  

  • 37. N3-substituted temozolomide analogs overcome methylguanine-DNA methyltransferase and mismatch repair precipitating apoptotic and autophagic cancer cell death.
    Zhang J; Hummersone M; Matthews CS; Stevens MF; Bradshaw TD
    Oncology; 2015; 88(1):28-48. PubMed ID: 25277441
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents.
    Liu L; Taverna P; Whitacre CM; Chatterjee S; Gerson SL
    Clin Cancer Res; 1999 Oct; 5(10):2908-17. PubMed ID: 10537360
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Repair of O6-carboxymethylguanine adducts by O6-methylguanine-DNA methyltransferase in human colon epithelial cells.
    Kostka T; Empl MT; Seiwert N; Geisen SM; Hoffmann P; Adam J; Seeger B; Shay JW; Christmann M; Sturla SJ; Fahrer J; Steinberg P
    Carcinogenesis; 2021 Aug; 42(8):1110-1118. PubMed ID: 34115837
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The proline rich domain of p53 is dispensable for MGMT-dependent DNA repair and cell survival following alkylation damage.
    Baran K; Yang M; Dillon CP; Samson LL; Green DR
    Cell Death Differ; 2017 Nov; 24(11):1925-1936. PubMed ID: 28753207
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.