BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 35230971)

  • 1. Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B.
    Kumar D; Kashyap MK; Yu Z; Spaanderman I; Villa R; Kipps TJ; La Clair JJ; Burkart MD; Castro JE
    Aging (Albany NY); 2022 Mar; 14(5):2081-2100. PubMed ID: 35230971
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B.
    Kashyap MK; Kumar D; Villa R; La Clair JJ; Benner C; Sasik R; Jones H; Ghia EM; Rassenti LZ; Kipps TJ; Burkart MD; Castro JE
    Haematologica; 2015 Jul; 100(7):945-54. PubMed ID: 25862704
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Therapy-induced stress response is associated with downregulation of pre-mRNA splicing in cancer cells.
    Anufrieva KS; Shender VО; Arapidi GP; Pavlyukov MS; Shakhparonov MI; Shnaider PV; Butenko IO; Lagarkova MA; Govorun VM
    Genome Med; 2018 Jun; 10(1):49. PubMed ID: 29950180
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apoptosis induction and cell cycle arrest of pladienolide B in erythroleukemia cell lines.
    Jorge J; Petronilho S; Alves R; Coucelo M; Gonçalves AC; Nascimento Costa JM; Sarmento-Ribeiro AB
    Invest New Drugs; 2020 Apr; 38(2):369-377. PubMed ID: 31147807
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of SF3b1 by pladienolide B evokes cycle arrest, apoptosis induction and p73 splicing in human cervical carcinoma cells.
    Zhang Q; Di C; Yan J; Wang F; Qu T; Wang Y; Chen Y; Zhang X; Liu Y; Yang H; Zhang H
    Artif Cells Nanomed Biotechnol; 2019 Dec; 47(1):1273-1280. PubMed ID: 30963795
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High antitumor activity of pladienolide B and its derivative in gastric cancer.
    Sato M; Muguruma N; Nakagawa T; Okamoto K; Kimura T; Kitamura S; Yano H; Sannomiya K; Goji T; Miyamoto H; Okahisa T; Mikasa H; Wada S; Iwata M; Takayama T
    Cancer Sci; 2014 Jan; 105(1):110-6. PubMed ID: 24635824
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds.
    Cretu C; Agrawal AA; Cook A; Will CL; Fekkes P; Smith PG; Lührmann R; Larsen N; Buonamici S; Pena V
    Mol Cell; 2018 Apr; 70(2):265-273.e8. PubMed ID: 29656923
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Splicing factor SF3b as a target of the antitumor natural product pladienolide.
    Kotake Y; Sagane K; Owa T; Mimori-Kiyosue Y; Shimizu H; Uesugi M; Ishihama Y; Iwata M; Mizui Y
    Nat Chem Biol; 2007 Sep; 3(9):570-5. PubMed ID: 17643112
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma.
    Sciarrillo R; Wojtuszkiewicz A; El Hassouni B; Funel N; Gandellini P; Lagerweij T; Buonamici S; Blijlevens M; Zeeuw van der Laan EA; Zaffaroni N; Deraco M; Kusamura S; Würdinger T; Peters GJ; Molthoff CFM; Jansen G; Kaspers GJL; Cloos J; Giovannetti E
    EBioMedicine; 2019 Jan; 39():215-225. PubMed ID: 30581150
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of RNA Splicing in Regulation of Cancer Stem Cell.
    Tripathi G; Tripathi A; Johnson J; Kashyap MK
    Curr Stem Cell Res Ther; 2023; 18(1):3-6. PubMed ID: 34875992
    [No Abstract]   [Full Text] [Related]  

  • 11. Biological validation that SF3b is a target of the antitumor macrolide pladienolide.
    Yokoi A; Kotake Y; Takahashi K; Kadowaki T; Matsumoto Y; Minoshima Y; Sugi NH; Sagane K; Hamaguchi M; Iwata M; Mizui Y
    FEBS J; 2011 Dec; 278(24):4870-80. PubMed ID: 21981285
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Splicing targeting drugs highlight intron retention as an actionable vulnerability in advanced prostate cancer.
    Naro C; Antonioni A; Medici V; Caggiano C; Jolly A; de la Grange P; Bielli P; Paronetto MP; Sette C
    J Exp Clin Cancer Res; 2024 Feb; 43(1):58. PubMed ID: 38413979
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stabilized cyclopropane analogs of the splicing inhibitor FD-895.
    Villa R; Kashyap MK; Kumar D; Kipps TJ; Castro JE; La Clair JJ; Burkart MD
    J Med Chem; 2013 Sep; 56(17):6576-82. PubMed ID: 23919277
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pre-mRNA splicing repression triggers abiotic stress signaling in plants.
    Ling Y; Alshareef S; Butt H; Lozano-Juste J; Li L; Galal AA; Moustafa A; Momin AA; Tashkandi M; Richardson DN; Fujii H; Arold S; Rodriguez PL; Duque P; Mahfouz MM
    Plant J; 2017 Jan; 89(2):291-309. PubMed ID: 27664942
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Splicing Factor 3b Subunit 1 (SF3B1) Reduced Cell Proliferation, Induced Apoptosis and Resulted in Cell Cycle Arrest by Regulating Homeobox A10 (HOXA10) Splicing in AGS and MKN28 Human Gastric Cancer Cells.
    Zhang Y; Yuan Z; Jiang Y; Shen R; Gu M; Xu W; Gu X
    Med Sci Monit; 2020 Jan; 26():e919460. PubMed ID: 31927557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Coherence between cellular responses and in vitro splicing inhibition for the anti-tumor drug pladienolide B and its analogs.
    Effenberger KA; Anderson DD; Bray WM; Prichard BE; Ma N; Adams MS; Ghosh AK; Jurica MS
    J Biol Chem; 2014 Jan; 289(4):1938-47. PubMed ID: 24302718
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug.
    Alors-Perez E; Blázquez-Encinas R; Alcalá S; Viyuela-García C; Pedraza-Arevalo S; Herrero-Aguayo V; Jiménez-Vacas JM; Mafficini A; Sánchez-Frías ME; Cano MT; Abollo-Jiménez F; Marín-Sanz JA; Cabezas-Sainz P; Lawlor RT; Luchini C; Sánchez L; Sánchez-Hidalgo JM; Ventura S; Martin-Hijano L; Gahete MD; Scarpa A; Arjona-Sánchez Á; Ibáñez-Costa A; Sainz B; Luque RM; Castaño JP
    J Exp Clin Cancer Res; 2021 Dec; 40(1):382. PubMed ID: 34857016
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemical Inhibition of Pre-mRNA Splicing in Living Saccharomyces cerevisiae.
    Hansen SR; Nikolai BJ; Spreacker PJ; Carrocci TJ; Hoskins AA
    Cell Chem Biol; 2019 Mar; 26(3):443-448.e3. PubMed ID: 30639260
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SF3B1 is a stress-sensitive splicing factor that regulates both HSF1 concentration and activity.
    Kim Guisbert KS; Guisbert E
    PLoS One; 2017; 12(4):e0176382. PubMed ID: 28445500
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enantioselective total synthesis of pladienolide B: a potent spliceosome inhibitor.
    Ghosh AK; Anderson DD
    Org Lett; 2012 Sep; 14(18):4730-3. PubMed ID: 22954141
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.