BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 35240686)

  • 1. Identification of novel γ-globin inducers among all potential erythroid druggable targets.
    Yu L; Myers G; Schneider E; Wang Y; Mathews R; Lim KC; Siemieniak D; Tang V; Ginsburg D; Balbin-Cuesta G; Singh SA; Phuwakanjana P; Jearawiriyapaisarn N; Khoriaty R; Engel JD
    Blood Adv; 2022 Jun; 6(11):3280-3285. PubMed ID: 35240686
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells.
    Chou YC; Chen RL; Lai ZS; Song JS; Chao YS; Shen CK
    Mol Cell Biol; 2015 Jul; 35(14):2541-53. PubMed ID: 25986606
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reactivation of Fetal Hemoglobin for Treating β-Thalassemia and Sickle Cell Disease.
    Cui S; Engel JD
    Adv Exp Med Biol; 2017; 1013():177-202. PubMed ID: 29127681
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.
    Traxler EA; Yao Y; Wang YD; Woodard KJ; Kurita R; Nakamura Y; Hughes JR; Hardison RC; Blobel GA; Li C; Weiss MJ
    Nat Med; 2016 Sep; 22(9):987-90. PubMed ID: 27525524
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
    Bao X; Zhang X; Wang L; Wang Z; Huang J; Zhang Q; Ye Y; Liu Y; Chen D; Zuo Y; Liu Q; Xu P; Huang B; Fang J; Lao J; Feng X; Li Y; Kurita R; Nakamura Y; Yu W; Ju C; Huang C; Mohandas N; Li D; Zhao C; Xu X
    Am J Hum Genet; 2021 Apr; 108(4):709-721. PubMed ID: 33735615
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cilostazol-mediated reversion of γ-globin silencing is associated with a high level of HbF production: A potential therapeutic candidate for β-globin disorders.
    Ali H; Khan F; Musharraf SG
    Biomed Pharmacother; 2021 Oct; 142():112058. PubMed ID: 34426256
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells.
    Qin K; Huang P; Feng R; Keller CA; Peslak SA; Khandros E; Saari MS; Lan X; Mayuranathan T; Doerfler PA; Abdulmalik O; Giardine B; Chou ST; Shi J; Hardison RC; Weiss MJ; Blobel GA
    Nat Genet; 2022 Jun; 54(6):874-884. PubMed ID: 35618846
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PUM1 mediates the posttranscriptional regulation of human fetal hemoglobin.
    Elagooz R; Dhara AR; Gott RM; Adams SE; White RA; Ghosh A; Ganguly S; Man Y; Owusu-Ansah A; Mian OY; Gurkan UA; Komar AA; Ramamoorthy M; Gnanapragasam MN
    Blood Adv; 2022 Dec; 6(23):6016-6022. PubMed ID: 35667093
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies.
    Iftikhar F; Khan MBN; Tehreem S; Kanwal N; Musharraf SG
    Bioorg Chem; 2023 Nov; 140():106768. PubMed ID: 37586133
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
    Ali H; Khan F; Ghulam Musharraf S
    Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bach1 inhibitor HPP-D mediates γ-globin gene activation in sickle erythroid progenitors.
    Palani CD; Zhu X; Alagar M; Attucks OC; Pace BS
    Blood Cells Mol Dis; 2024 Jan; 104():102792. PubMed ID: 37633023
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway.
    Macari ER; Lowrey CH
    Blood; 2011 Jun; 117(22):5987-97. PubMed ID: 21464371
    [TBL] [Abstract][Full Text] [Related]  

  • 13. When basic science reaches into rational therapeutic design: from historical to novel leads for the treatment of β-globinopathies.
    Andrieu-Soler C; Soler E
    Curr Opin Hematol; 2020 May; 27(3):141-148. PubMed ID: 32167946
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Plastrum testudinis induces γ-globin gene expression through epigenetic histone modifications within the γ-globin gene promoter via activation of the p38 MAPK signaling pathway.
    Qian X; Chen J; Zhao D; Guo L; Qian X
    Int J Mol Med; 2013 Jun; 31(6):1418-28. PubMed ID: 23588991
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal development.
    McConnell SC; Huo Y; Liu S; Ryan TM
    Mol Cell Biol; 2011 Feb; 31(4):876-83. PubMed ID: 21173165
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters.
    Breveglieri G; Salvatori F; Finotti A; Cosenza LC; Zuccato C; Bianchi N; Breda L; Rivella S; Bresciani A; Bisbocci M; Borgatti M; Gambari R
    Anal Bioanal Chem; 2019 Nov; 411(29):7669-7680. PubMed ID: 31273412
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
    Wilber A; Hargrove PW; Kim YS; Riberdy JM; Sankaran VG; Papanikolaou E; Georgomanoli M; Anagnou NP; Orkin SH; Nienhuis AW; Persons DA
    Blood; 2011 Mar; 117(10):2817-26. PubMed ID: 21156846
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Epigenetic regulation of fetal globin gene expression in adult erythroid cells.
    Ginder GD
    Transl Res; 2015 Jan; 165(1):115-25. PubMed ID: 24880147
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina.
    Promsote W; Makala L; Li B; Smith SB; Singh N; Ganapathy V; Pace BS; Martin PM
    Invest Ophthalmol Vis Sci; 2014 May; 55(8):5382-93. PubMed ID: 24825111
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of fetal hemoglobin through enhanced translation efficiency of γ-globin mRNA.
    Hahn CK; Lowrey CH
    Blood; 2014 Oct; 124(17):2730-4. PubMed ID: 25170120
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.