174 related articles for article (PubMed ID: 35245608)
1. Heterozygous Dnmt3a R878C induces expansion of quiescent hematopoietic stem cell pool.
Higo T; Suzuki Y; Sato M; Koya J; Mizuno H; Miyauchi M; Masamoto Y; Kataoka K; Sumitomo Y; Tsuruta-Kishino T; Sato T; Kurokawa M
Exp Hematol; 2022 May; 109():45-54. PubMed ID: 35245608
[TBL] [Abstract][Full Text] [Related]
2. Txnip Enhances Fitness of Dnmt3a-Mutant Hematopoietic Stem Cells via p21.
Zhang CR; Ostrander EL; Kukhar O; Mallaney C; Sun J; Haussler E; Celik H; Koh WK; King KY; Gontarz P; Challen GA
Blood Cancer Discov; 2022 May; 3(3):220-239. PubMed ID: 35394496
[TBL] [Abstract][Full Text] [Related]
3. Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo.
Jeong M; Park HJ; Celik H; Ostrander EL; Reyes JM; Guzman A; Rodriguez B; Lei Y; Lee Y; Ding L; Guryanova OA; Li W; Goodell MA; Challen GA
Cell Rep; 2018 Apr; 23(1):1-10. PubMed ID: 29617651
[TBL] [Abstract][Full Text] [Related]
4. Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling.
Hormaechea-Agulla D; Matatall KA; Le DT; Kain B; Long X; Kus P; Jaksik R; Challen GA; Kimmel M; King KY
Cell Stem Cell; 2021 Aug; 28(8):1428-1442.e6. PubMed ID: 33743191
[TBL] [Abstract][Full Text] [Related]
5. Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
Tovy A; Reyes JM; Gundry MC; Brunetti L; Lee-Six H; Petljak M; Park HJ; Guzman AG; Rosas C; Jeffries AR; Baple E; Mill J; Crosby AH; Sency V; Xin B; Machado HE; Castillo D; Weitzel JN; Li W; Stratton MR; Campbell PJ; Wang H; Sanders MA; Goodell MA
Cell Stem Cell; 2020 Aug; 27(2):326-335.e4. PubMed ID: 32673568
[TBL] [Abstract][Full Text] [Related]
6. Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis.
Zioni N; Bercovich AA; Chapal-Ilani N; Bacharach T; Rappoport N; Solomon A; Avraham R; Kopitman E; Porat Z; Sacma M; Hartmut G; Scheller M; Muller-Tidow C; Lipka D; Shlush E; Minden M; Kaushansky N; Shlush LI
Nat Commun; 2023 Apr; 14(1):2070. PubMed ID: 37045808
[TBL] [Abstract][Full Text] [Related]
7. Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response.
Scheller M; Ludwig AK; Göllner S; Rohde C; Krämer S; Stäble S; Janssen M; Müller JA; He L; Bäumer N; Arnold C; Gerß J; Schönung M; Thiede C; Niederwieser C; Niederwieser D; Serve H; Berdel WE; Thiem U; Hemmerling I; Leuschner F; Plass C; Schlesner M; Zaugg J; Milsom MD; Trumpp A; Pabst C; Lipka DB; Müller-Tidow C
Nat Cancer; 2021 May; 2(5):527-544. PubMed ID: 35122024
[TBL] [Abstract][Full Text] [Related]
8. CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease.
Sano S; Oshima K; Wang Y; Katanasaka Y; Sano M; Walsh K
Circ Res; 2018 Jul; 123(3):335-341. PubMed ID: 29728415
[TBL] [Abstract][Full Text] [Related]
9. Divergent Effects of Dnmt3a and Tet2 Mutations on Hematopoietic Progenitor Cell Fitness.
Ostrander EL; Kramer AC; Mallaney C; Celik H; Koh WK; Fairchild J; Haussler E; Zhang CRC; Challen GA
Stem Cell Reports; 2020 Apr; 14(4):551-560. PubMed ID: 32220332
[TBL] [Abstract][Full Text] [Related]
10. Dnmt3a-null hematopoietic stem and progenitor cells expand after busulfan treatment.
Chen J; Matatall KA; Feng X; Hormaechea-Agulla D; Maharjan M; Young N; King KY
Exp Hematol; 2020 Nov; 91():39-45.e2. PubMed ID: 32961298
[TBL] [Abstract][Full Text] [Related]
11. Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.
Nam AS; Dusaj N; Izzo F; Murali R; Myers RM; Mouhieddine TH; Sotelo J; Benbarche S; Waarts M; Gaiti F; Tahri S; Levine R; Abdel-Wahab O; Godley LA; Chaligne R; Ghobrial I; Landau DA
Nat Genet; 2022 Oct; 54(10):1514-1526. PubMed ID: 36138229
[TBL] [Abstract][Full Text] [Related]
12. Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome.
Tovy A; Rosas C; Gaikwad AS; Medrano G; Zhang L; Reyes JM; Huang YH; Arakawa T; Kurtz K; Conneely SE; Guzman AG; Aguilar R; Gao A; Chen CW; Kim JJ; Carter MT; Lasa-Aranzasti A; Valenzuela I; Van Maldergem L; Brunetti L; Hicks MJ; Marcogliese AN; Goodell MA; Rau RE
Haematologica; 2022 Apr; 107(4):887-898. PubMed ID: 34092059
[TBL] [Abstract][Full Text] [Related]
13. miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a.
Hu W; Dooley J; Chung SS; Chandramohan D; Cimmino L; Mukherjee S; Mason CE; de Strooper B; Liston A; Park CY
Blood; 2015 Apr; 125(14):2206-16. PubMed ID: 25634742
[TBL] [Abstract][Full Text] [Related]
14. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies.
Cole CB; Russler-Germain DA; Ketkar S; Verdoni AM; Smith AM; Bangert CV; Helton NM; Guo M; Klco JM; O'Laughlin S; Fronick C; Fulton R; Chang GS; Petti AA; Miller CA; Ley TJ
J Clin Invest; 2017 Oct; 127(10):3657-3674. PubMed ID: 28872462
[TBL] [Abstract][Full Text] [Related]
15. Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation.
Cypris O; Franzen J; Frobel J; Glück P; Kuo CC; Schmitz S; Nüchtern S; Zenke M; Wagner W
BMC Biol; 2022 Jun; 20(1):141. PubMed ID: 35705990
[TBL] [Abstract][Full Text] [Related]
16. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.
Fujino T; Goyama S; Sugiura Y; Inoue D; Asada S; Yamasaki S; Matsumoto A; Yamaguchi K; Isobe Y; Tsuchiya A; Shikata S; Sato N; Morinaga H; Fukuyama T; Tanaka Y; Fukushima T; Takeda R; Yamamoto K; Honda H; Nishimura EK; Furukawa Y; Shibata T; Abdel-Wahab O; Suematsu M; Kitamura T
Nat Commun; 2021 Mar; 12(1):1826. PubMed ID: 33758188
[TBL] [Abstract][Full Text] [Related]
17. [Functional role of DNMT3A mutation in acute myeloid leukemia].
Koya J; Kurokawa M
Rinsho Ketsueki; 2018; 59(5):602-610. PubMed ID: 29877252
[TBL] [Abstract][Full Text] [Related]
18. Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells.
Guryanova OA; Lieu YK; Garrett-Bakelman FE; Spitzer B; Glass JL; Shank K; Martinez AB; Rivera SA; Durham BH; Rapaport F; Keller MD; Pandey S; Bastian L; Tovbin D; Weinstein AR; Teruya-Feldstein J; Abdel-Wahab O; Santini V; Mason CE; Melnick AM; Mukherjee S; Levine RL
Leukemia; 2016 May; 30(5):1133-42. PubMed ID: 26710888
[TBL] [Abstract][Full Text] [Related]
19. Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis.
Liao M; Dong Q; Chen R; Xu L; Jiang Y; Guo Z; Xiao M; He W; Cao C; Hu R; Sun W; Jiang H; Wang J
Cell Death Discov; 2021 Oct; 7(1):297. PubMed ID: 34663800
[TBL] [Abstract][Full Text] [Related]
20. Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders.
Midic D; Rinke J; Perner F; Müller V; Hinze A; Pester F; Landschulze J; Ernst J; Gruhn B; Matziolis G; Heidel FH; Hochhaus A; Ernst T
Leukemia; 2020 Aug; 34(8):2198-2205. PubMed ID: 32457355
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]