BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 35251038)

  • 1. A Critical Function for the Transcription Factors GLI1 and GLI2 in the Proliferation and Survival of Human Mast Cells.
    Falduto GH; Pfeiffer A; Zhang Q; Yin Y; Metcalfe DD; Olivera A
    Front Immunol; 2022; 13():841045. PubMed ID: 35251038
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
    Mazumdar T; DeVecchio J; Agyeman A; Shi T; Houghton JA
    Oncotarget; 2011 Aug; 2(8):638-45. PubMed ID: 21860067
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.
    Tolosa EJ; Fernandez-Barrena MG; Iguchi E; McCleary-Wheeler AL; Carr RM; Almada LL; Flores LF; Vera RE; Alfonse GW; Marks DL; Hogenson TL; Vrabel AM; Horn IP; Koenig AN; Safgren SL; Sigafoos AN; Erkan M; Romecin-Duran PA; Sarabia Gonzalez A; Zhou B; Javelaud D; Marsaud V; Graham RP; Mauviel A; Elsawa SF; Fernandez-Zapico ME
    Biochem J; 2020 Sep; 477(17):3131-3145. PubMed ID: 32766732
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.
    Tang CM; Lee TE; Syed SA; Burgoyne AM; Leonard SY; Gao F; Chan JC; Shi E; Chmielecki J; Morosini D; Wang K; Ross JS; Kendrick ML; Bardsley MR; Siena M; Mao J; Harismendy O; Ordog T; Sicklick JK
    Oncotarget; 2016 Nov; 7(48):78226-78241. PubMed ID: 27793025
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth.
    Maresca L; Crivaro E; Migliorini F; Anichini G; Giammona A; Pepe S; Poggialini F; Vagaggini C; Giannini G; Sestini S; Borgognoni L; Lapucci A; Dreassi E; Taddei M; Manetti F; Petricci E; Stecca B
    Pharmacol Res; 2023 Sep; 195():106858. PubMed ID: 37473878
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth.
    Pandolfi S; Montagnani V; Lapucci A; Stecca B
    Cell Death Differ; 2015 Dec; 22(12):2006-19. PubMed ID: 26024388
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GANT-61 and GDC-0449 induce apoptosis of prostate cancer stem cells through a GLI-dependent mechanism.
    Tong W; Qiu L; Qi M; Liu J; Hu K; Lin W; Huang Y; Fu J
    J Cell Biochem; 2018 Apr; 119(4):3641-3652. PubMed ID: 29231999
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling.
    Harada K; Ohashi R; Naito K; Kanki K
    Int J Mol Sci; 2020 Apr; 21(9):. PubMed ID: 32354204
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis.
    Wu M; Ingram L; Tolosa EJ; Vera RE; Li Q; Kim S; Ma Y; Spyropoulos DD; Beharry Z; Huang J; Fernandez-Zapico ME; Cai H
    J Biol Chem; 2016 Dec; 291(49):25749-25760. PubMed ID: 27760825
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of GLI-SOX2 signaling axis for gemcitabine resistance in pancreatic cancer.
    Jia Y; Gu D; Wan J; Yu B; Zhang X; Chiorean EG; Wang Y; Xie J
    Oncogene; 2019 Mar; 38(10):1764-1777. PubMed ID: 30382189
    [TBL] [Abstract][Full Text] [Related]  

  • 11. mTORC2 regulates hedgehog pathway activity by promoting stability to Gli2 protein and its nuclear translocation.
    Maiti S; Mondal S; Satyavarapu EM; Mandal C
    Cell Death Dis; 2017 Jul; 8(7):e2926. PubMed ID: 28703798
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog.
    Ruiz i Altaba A
    Development; 1998 Jun; 125(12):2203-12. PubMed ID: 9584120
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct repression of anoctamin 1 (
    Mazzone A; Gibbons SJ; Eisenman ST; Strege PR; Zheng T; D'Amato M; Ordog T; Fernandez-Zapico ME; Farrugia G
    FASEB J; 2019 May; 33(5):6632-6642. PubMed ID: 30802137
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
    Agyeman A; Mazumdar T; Houghton JA
    Oncotarget; 2012 Aug; 3(8):854-68. PubMed ID: 23097684
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Abnormal activity of transcription factors gli in high-grade gliomas.
    Volnitskiy A; Shtam T; Burdakov V; Kovalev R; Konev A; Filatov M
    PLoS One; 2019; 14(2):e0211980. PubMed ID: 30730955
    [TBL] [Abstract][Full Text] [Related]  

  • 16. GLI2 promotes cell proliferation and migration through transcriptional activation of ARHGEF16 in human glioma cells.
    Huang D; Wang Y; Xu L; Chen L; Cheng M; Shi W; Xiong H; Zalli D; Luo S
    J Exp Clin Cancer Res; 2018 Oct; 37(1):247. PubMed ID: 30305138
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2.
    Regl G; Kasper M; Schnidar H; Eichberger T; Neill GW; Philpott MP; Esterbauer H; Hauser-Kronberger C; Frischauf AM; Aberger F
    Cancer Res; 2004 Nov; 64(21):7724-31. PubMed ID: 15520176
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gli function is essential for motor neuron induction in zebrafish.
    Vanderlaan G; Tyurina OV; Karlstrom RO; Chandrasekhar A
    Dev Biol; 2005 Jun; 282(2):550-70. PubMed ID: 15890329
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.
    Scicchitano S; Giordano M; Lucchino V; Montalcini Y; Chiarella E; Aloisio A; Codispoti B; Zoppoli P; Melocchi V; Bianchi F; De Smaele E; Mesuraca M; Morrone G; Bond HM
    Cell Death Dis; 2019 Sep; 10(10):715. PubMed ID: 31558698
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
    Mazumdar T; Devecchio J; Agyeman A; Shi T; Houghton JA
    Cancer Res; 2011 Sep; 71(17):5904-14. PubMed ID: 21747117
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.