BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 35256939)

  • 21. Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis.
    Loberg MA; Bell RK; Goodwin LO; Eudy E; Miles LA; SanMiguel JM; Young K; Bergstrom DE; Levine RL; Schneider RK; Trowbridge JJ
    Leukemia; 2019 Jul; 33(7):1635-1649. PubMed ID: 30692594
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia.
    Berenstein R; Blau IW; Suckert N; Baldus C; Pezzutto A; Dörken B; Blau O
    J Exp Clin Cancer Res; 2015 May; 34(1):55. PubMed ID: 25994761
    [TBL] [Abstract][Full Text] [Related]  

  • 23. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
    Rickard JA; O'Donnell JA; Evans JM; Lalaoui N; Poh AR; Rogers T; Vince JE; Lawlor KE; Ninnis RL; Anderton H; Hall C; Spall SK; Phesse TJ; Abud HE; Cengia LH; Corbin J; Mifsud S; Di Rago L; Metcalf D; Ernst M; Dewson G; Roberts AW; Alexander WS; Murphy JM; Ekert PG; Masters SL; Vaux DL; Croker BA; Gerlic M; Silke J
    Cell; 2014 May; 157(5):1175-88. PubMed ID: 24813849
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Dnmt3a-null hematopoietic stem and progenitor cells expand after busulfan treatment.
    Chen J; Matatall KA; Feng X; Hormaechea-Agulla D; Maharjan M; Young N; King KY
    Exp Hematol; 2020 Nov; 91():39-45.e2. PubMed ID: 32961298
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Remethylation of
    Ketkar S; Verdoni AM; Smith AM; Bangert CV; Leight ER; Chen DY; Brune MK; Helton NM; Hoock M; George DR; Fronick C; Fulton RS; Ramakrishnan SM; Chang GS; Petti AA; Spencer DH; Miller CA; Ley TJ
    Proc Natl Acad Sci U S A; 2020 Feb; 117(6):3123-3134. PubMed ID: 31996479
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Clonal Hematopoiesis-Driver DNMT3A Mutations Alter Immune Cells in Heart Failure.
    Abplanalp WT; Cremer S; John D; Hoffmann J; Schuhmacher B; Merten M; Rieger MA; Vasa-Nicotera M; Zeiher AM; Dimmeler S
    Circ Res; 2021 Jan; 128(2):216-228. PubMed ID: 33155517
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity.
    Nguyen TV; Yao S; Wang Y; Rolfe A; Selvaraj A; Darman R; Ke J; Warmuth M; Smith PG; Larsen NA; Yu L; Zhu P; Fekkes P; Vaillancourt FH; Bolduc DM
    J Biol Chem; 2019 Nov; 294(45):16966-16977. PubMed ID: 31582562
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Clonal hematopoiesis and risk of acute myeloid leukemia.
    Young AL; Tong RS; Birmann BM; Druley TE
    Haematologica; 2019 Dec; 104(12):2410-2417. PubMed ID: 31004019
    [TBL] [Abstract][Full Text] [Related]  

  • 29. DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice.
    Scourzic L; Couronné L; Pedersen MT; Della Valle V; Diop M; Mylonas E; Calvo J; Mouly E; Lopez CK; Martin N; Fontenay M; Bender A; Guibert S; Dubreuil P; Dessen P; Droin N; Pflumio F; Weber M; Gaulard P; Helin K; Mercher T; Bernard OA
    Leukemia; 2016 Jun; 30(6):1388-98. PubMed ID: 26876596
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Acute myeloid leukemia derived from lympho-myeloid clonal hematopoiesis.
    Thol F; Klesse S; Köhler L; Gabdoulline R; Kloos A; Liebich A; Wichmann M; Chaturvedi A; Fabisch J; Gaidzik VI; Paschka P; Bullinger L; Bug G; Serve H; Göhring G; Schlegelberger B; Lübbert M; Kirchner H; Wattad M; Kraemer D; Hertenstein B; Heil G; Fiedler W; Krauter J; Schlenk RF; Döhner K; Döhner H; Ganser A; Heuser M
    Leukemia; 2017 Jun; 31(6):1286-1295. PubMed ID: 27881874
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis.
    SanMiguel JM; Eudy E; Loberg MA; Young KA; Mistry JJ; Mujica KD; Schwartz LS; Stearns TM; Challen GA; Trowbridge JJ
    Cancer Discov; 2022 Dec; 12(12):2763-2773. PubMed ID: 36169447
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Clonal hematopoiesis as determined by the HUMARA assay is a marker for acquired mutations in epigenetic regulators in older women.
    Wiedmeier JE; Kato C; Zhang Z; Lee H; Dunlap J; Nutt E; Rattray R; McKay S; Eide C; Press R; Mori M; Druker B; Dao KH
    Exp Hematol; 2016 Sep; 44(9):857-865.e5. PubMed ID: 27235757
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Persistent DNMT3A mutation burden in DNMT3A mutated adult cytogenetically normal acute myeloid leukemia patients in long-term remission.
    Sun Y; Shen H; Xu T; Yang Z; Qiu H; Sun A; Chen S; Wu D; Xu Y
    Leuk Res; 2016 Oct; 49():102-7. PubMed ID: 27626217
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Clonal Hematopoiesis, Cardiovascular Diseases and Hematopoietic Stem Cells.
    Kandarakov O; Belyavsky A
    Int J Mol Sci; 2020 Oct; 21(21):. PubMed ID: 33114351
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis.
    Roderick JE; Hermance N; Zelic M; Simmons MJ; Polykratis A; Pasparakis M; Kelliher MA
    Proc Natl Acad Sci U S A; 2014 Oct; 111(40):14436-41. PubMed ID: 25246544
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Aging and leukemic evolution of hematopoietic stem cells under various stress conditions.
    Kurosawa S; Iwama A
    Inflamm Regen; 2020 Nov; 40(1):29. PubMed ID: 33292805
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.
    Chang YI; You X; Kong G; Ranheim EA; Wang J; Du J; Liu Y; Zhou Y; Ryu MJ; Zhang J
    Leukemia; 2015 Sep; 29(9):1847-56. PubMed ID: 25801914
    [TBL] [Abstract][Full Text] [Related]  

  • 38. DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia.
    Gaidzik VI; Weber D; Paschka P; Kaumanns A; Krieger S; Corbacioglu A; Krönke J; Kapp-Schwoerer S; Krämer D; Horst HA; Schmidt-Wolf I; Held G; Kündgen A; Ringhoffer M; Götze K; Kindler T; Fiedler W; Wattad M; Schlenk RF; Bullinger L; Teleanu V; Schlegelberger B; Thol F; Heuser M; Ganser A; Döhner H; Döhner K;
    Leukemia; 2018 Jan; 32(1):30-37. PubMed ID: 28643785
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inflammatory Modulation of Hematopoiesis: Linking Trained Immunity and Clonal Hematopoiesis with Chronic Disorders.
    Chavakis T; Wielockx B; Hajishengallis G
    Annu Rev Physiol; 2022 Feb; 84():183-207. PubMed ID: 34614373
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development.
    Lu R; Wang P; Parton T; Zhou Y; Chrysovergis K; Rockowitz S; Chen WY; Abdel-Wahab O; Wade PA; Zheng D; Wang GG
    Cancer Cell; 2016 Jul; 30(1):92-107. PubMed ID: 27344947
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.