BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 35259014)

  • 1. Poly-dipeptides produced from
    Jo Y; Lee J; Lee SY; Kwon I; Cho H
    Proc Natl Acad Sci U S A; 2022 Mar; 119(11):e2113813119. PubMed ID: 35259014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.
    Kanekura K; Yagi T; Cammack AJ; Mahadevan J; Kuroda M; Harms MB; Miller TM; Urano F
    Hum Mol Genet; 2016 May; 25(9):1803-13. PubMed ID: 26931465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pathogenesis underlying hexanucleotide repeat expansions in
    Chong ZZ; Menkes DL; Souayah N
    Rev Neurosci; 2024 Jan; 35(1):85-97. PubMed ID: 37525497
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity.
    Xu W; Bao P; Jiang X; Wang H; Qin M; Wang R; Wang T; Yang Y; Lorenzini I; Liao L; Sattler R; Xu J
    Brain; 2019 May; 142(5):1349-1364. PubMed ID: 30938419
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis.
    Farg MA; Konopka A; Soo KY; Ito D; Atkin JD
    Hum Mol Genet; 2017 Aug; 26(15):2882-2896. PubMed ID: 28481984
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR.
    Hao Z; Liu L; Tao Z; Wang R; Ren H; Sun H; Lin Z; Zhang Z; Mu C; Zhou J; Wang G
    Nat Commun; 2019 Jul; 10(1):2906. PubMed ID: 31266945
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.
    Gomez-Deza J; Lee YB; Troakes C; Nolan M; Al-Sarraj S; Gallo JM; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():38. PubMed ID: 26108573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
    Peters OM; Cabrera GT; Tran H; Gendron TF; McKeon JE; Metterville J; Weiss A; Wightman N; Salameh J; Kim J; Sun H; Boylan KB; Dickson D; Kennedy Z; Lin Z; Zhang YJ; Daughrity L; Jung C; Gao FB; Sapp PC; Horvitz HR; Bosco DA; Brown SP; de Jong P; Petrucelli L; Mueller C; Brown RH
    Neuron; 2015 Dec; 88(5):902-909. PubMed ID: 26637797
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heterochromatin anomalies and double-stranded RNA accumulation underlie
    Zhang YJ; Guo L; Gonzales PK; Gendron TF; Wu Y; Jansen-West K; O'Raw AD; Pickles SR; Prudencio M; Carlomagno Y; Gachechiladze MA; Ludwig C; Tian R; Chew J; DeTure M; Lin WL; Tong J; Daughrity LM; Yue M; Song Y; Andersen JW; Castanedes-Casey M; Kurti A; Datta A; Antognetti G; McCampbell A; Rademakers R; Oskarsson B; Dickson DW; Kampmann M; Ward ME; Fryer JD; Link CD; Shorter J; Petrucelli L
    Science; 2019 Feb; 363(6428):. PubMed ID: 30765536
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disrupted phase behavior of FUS underlies poly-PR-induced DNA damage in amyotrophic lateral sclerosis.
    Wang Y; Liu L; Chen H; Yang Y; Mu C; Ren H; Liu Y; Yu L; Fang Q; Wang G; Hao Z
    Hum Mol Genet; 2023 Dec; 33(1):64-77. PubMed ID: 37756636
    [TBL] [Abstract][Full Text] [Related]  

  • 11. C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in
    Xu W; Xu J
    J Neurosci; 2018 Aug; 38(35):7741-7752. PubMed ID: 30037833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA.
    Suzuki H; Matsuoka M
    J Neurochem; 2021 Aug; 158(3):753-765. PubMed ID: 34081786
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model.
    Swaminathan A; Bouffard M; Liao M; Ryan S; Callister JB; Pickering-Brown SM; Armstrong GAB; Drapeau P
    Hum Mol Genet; 2018 May; 27(10):1754-1762. PubMed ID: 29528390
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
    Sonobe Y; Aburas J; Krishnan G; Fleming AC; Ghadge G; Islam P; Warren EC; Gu Y; Kankel MW; Brown AEX; Kiskinis E; Gendron TF; Gao FB; Roos RP; Kratsios P
    Nat Commun; 2021 Oct; 12(1):6025. PubMed ID: 34654821
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular Mechanisms of Neurodegeneration Related to
    Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
    Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death.
    Wen X; Tan W; Westergard T; Krishnamurthy K; Markandaiah SS; Shi Y; Lin S; Shneider NA; Monaghan J; Pandey UB; Pasinelli P; Ichida JK; Trotti D
    Neuron; 2014 Dec; 84(6):1213-25. PubMed ID: 25521377
    [TBL] [Abstract][Full Text] [Related]  

  • 17. C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
    Dafinca R; Scaber J; Ababneh N; Lalic T; Weir G; Christian H; Vowles J; Douglas AG; Fletcher-Jones A; Browne C; Nakanishi M; Turner MR; Wade-Martins R; Cowley SA; Talbot K
    Stem Cells; 2016 Aug; 34(8):2063-78. PubMed ID: 27097283
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.
    Yin S; Lopez-Gonzalez R; Kunz RC; Gangopadhyay J; Borufka C; Gygi SP; Gao FB; Reed R
    Cell Rep; 2017 Jun; 19(11):2244-2256. PubMed ID: 28614712
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The proline-arginine repeat protein linked to C9-ALS/FTD causes neuronal toxicity by inhibiting the DEAD-box RNA helicase-mediated ribosome biogenesis.
    Suzuki H; Shibagaki Y; Hattori S; Matsuoka M
    Cell Death Dis; 2018 Sep; 9(10):975. PubMed ID: 30250194
    [TBL] [Abstract][Full Text] [Related]  

  • 20. C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration.
    May S; Hornburg D; Schludi MH; Arzberger T; Rentzsch K; Schwenk BM; Grässer FA; Mori K; Kremmer E; Banzhaf-Strathmann J; Mann M; Meissner F; Edbauer D
    Acta Neuropathol; 2014 Oct; 128(4):485-503. PubMed ID: 25120191
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.