BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 35268423)

  • 1. Efficacy of Flotetuzumab in Combination with Cytarabine in Patient-Derived Xenograft Models of Pediatric Acute Myeloid Leukemia.
    Barwe SP; Kisielewski A; Bonvini E; Muth J; Davidson-Moncada J; Kolb EA; Gopalakrishnapillai A
    J Clin Med; 2022 Feb; 11(5):. PubMed ID: 35268423
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A CD3xCD123 bispecific DART for redirecting host T cells to myelogenous leukemia: preclinical activity and safety in nonhuman primates.
    Chichili GR; Huang L; Li H; Burke S; He L; Tang Q; Jin L; Gorlatov S; Ciccarone V; Chen F; Koenig S; Shannon M; Alderson R; Moore PA; Johnson S; Bonvini E
    Sci Transl Med; 2015 May; 7(289):289ra82. PubMed ID: 26019218
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Integrated Pharmacokinetic/Pharmacodynamic Model of a Bispecific CD3xCD123 DART Molecule in Nonhuman Primates: Evaluation of Activity and Impact of Immunogenicity.
    Campagne O; Delmas A; Fouliard S; Chenel M; Chichili GR; Li H; Alderson R; Scherrmann JM; Mager DE
    Clin Cancer Res; 2018 Jun; 24(11):2631-2641. PubMed ID: 29463552
    [No Abstract]   [Full Text] [Related]  

  • 4. Targeting CD123 in acute myeloid leukemia using a T-cell-directed dual-affinity retargeting platform.
    Al-Hussaini M; Rettig MP; Ritchey JK; Karpova D; Uy GL; Eissenberg LG; Gao F; Eades WC; Bonvini E; Chichili GR; Moore PA; Johnson S; Collins L; DiPersio JF
    Blood; 2016 Jan; 127(1):122-31. PubMed ID: 26531164
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML.
    Vadakekolathu J; Lai C; Reeder S; Church SE; Hood T; Lourdusamy A; Rettig MP; Aldoss I; Advani AS; Godwin J; Wieduwilt MJ; Arellano M; Muth J; Yau TO; Ravandi F; Sweet K; Altmann H; Foulds GA; Stölzel F; Middeke JM; Ciciarello M; Curti A; Valk PJM; Löwenberg B; Gojo I; Bornhäuser M; DiPersio JF; Davidson-Moncada JK; Rutella S
    Blood Adv; 2020 Oct; 4(20):5011-5024. PubMed ID: 33057635
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transgenic Expression of IL15 Retains CD123-Redirected T Cells in a Less Differentiated State Resulting in Improved Anti-AML Activity in Autologous AML PDX Models.
    Mu-Mosley H; Ostermann L; Muftuoglu M; Vaidya A; Bonifant CL; Velasquez MP; Gottschalk S; Andreeff M
    Front Immunol; 2022; 13():880108. PubMed ID: 35615350
    [TBL] [Abstract][Full Text] [Related]  

  • 7. T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia.
    Mardiros A; Dos Santos C; McDonald T; Brown CE; Wang X; Budde LE; Hoffman L; Aguilar B; Chang WC; Bretzlaff W; Chang B; Jonnalagadda M; Starr R; Ostberg JR; Jensen MC; Bhatia R; Forman SJ
    Blood; 2013 Oct; 122(18):3138-48. PubMed ID: 24030378
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Flotetuzumab and other T-cell immunotherapies upregulate MHC class II expression on acute myeloid leukemia cells.
    Rimando JC; Chendamarai E; Rettig MP; Jayasinghe R; Christopher MJ; Ritchey JK; Christ S; Kim MY; Bonvini E; DiPersio JF
    Blood; 2023 Apr; 141(14):1718-1723. PubMed ID: 36563336
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of a novel fully-human anti-CD123 antibody to target acute myeloid leukemia.
    Hutmacher C; Volta L; Rinaldi F; Murer P; Myburgh R; Manz MG; Neri D
    Leuk Res; 2019 Sep; 84():106178. PubMed ID: 31326578
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia.
    Bonifant CL; Szoor A; Torres D; Joseph N; Velasquez MP; Iwahori K; Gaikwad A; Nguyen P; Arber C; Song XT; Redell M; Gottschalk S
    Mol Ther; 2016 Sep; 24(9):1615-26. PubMed ID: 27401038
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bispecific Antibodies for the Treatment of Acute Myeloid Leukemia.
    Guy DG; Uy GL
    Curr Hematol Malig Rep; 2018 Dec; 13(6):417-425. PubMed ID: 30280288
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pre-clinical development of a novel CD3-CD123 bispecific T-cell engager using cross-over dual-variable domain (CODV) format for acute myeloid leukemia (AML) treatment.
    Bonnevaux H; Guerif S; Albrecht J; Jouannot E; De Gallier T; Beil C; Lange C; Leuschner WD; Schneider M; Lemoine C; Caron A; Amara C; Barrière C; Siavellis J; Bardet V; Luna E; Agrawal P; Drake DR; Rao E; Wonerow P; Carrez C; Blanc V; Hsu K; Wiederschain D; Fraenkel PG; Virone-Oddos A
    Oncoimmunology; 2021; 10(1):1945803. PubMed ID: 34484869
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An Update on the Clinical Evaluation of Antibody-Based Therapeutics in Acute Myeloid Leukemia.
    Venugopal S; Daver N; Ravandi F
    Curr Hematol Malig Rep; 2021 Feb; 16(1):89-96. PubMed ID: 33630233
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Flotetuzumab as a salvage immunotherapy in advanced CD123-positive hematological malignancies, a phase 1 pilot study.
    Aldoss I; Zhang J; Robbins M; Song J; Al Malki MM; Otoukesh S; Sandhu K; Agrawal V; Herrera AF; Popplewell LL; Ghoda L; Stein A; Marcucci G; Forman S; Pullarkat V
    Leuk Lymphoma; 2024 Apr; ():1-9. PubMed ID: 38629176
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting the alpha subunit of IL-3 receptor (CD123) in patients with acute leukemia.
    Aldoss I; Clark M; Song JY; Pullarkat V
    Hum Vaccin Immunother; 2020 Oct; 16(10):2341-2348. PubMed ID: 32692611
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bispecific antibody-targeted T-cell therapy for acute myeloid leukemia.
    Kubicka E; Lum LG; Huang M; Thakur A
    Front Immunol; 2022; 13():899468. PubMed ID: 36389764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Safe and effective off-the-shelf immunotherapy based on CAR.CD123-NK cells for the treatment of acute myeloid leukaemia.
    Caruso S; De Angelis B; Del Bufalo F; Ciccone R; Donsante S; Volpe G; Manni S; Guercio M; Pezzella M; Iaffaldano L; Silvestris DA; Sinibaldi M; Di Cecca S; Pitisci A; Velardi E; Merli P; Algeri M; Lodi M; Paganelli V; Serafini M; Riminucci M; Locatelli F; Quintarelli C
    J Hematol Oncol; 2022 Nov; 15(1):163. PubMed ID: 36335396
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Emodin and Its Combination with Cytarabine Induce Apoptosis in Resistant Acute Myeloid Leukemia Cells in Vitro and in Vivo.
    Chen Y; Gan D; Huang Q; Luo X; Lin D; Hu J
    Cell Physiol Biochem; 2018; 48(5):2061-2073. PubMed ID: 30099447
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient mice.
    Lee EM; Yee D; Busfield SJ; McManus JF; Cummings N; Vairo G; Wei A; Ramshaw HS; Powell JA; Lopez AF; Lewis ID; McCall MN; Lock RB
    Haematologica; 2015 Jul; 100(7):914-26. PubMed ID: 26130514
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Improved Activity against Acute Myeloid Leukemia with Chimeric Antigen Receptor (CAR)-NK-92 Cells Designed to Target CD123.
    Morgan MA; Kloos A; Lenz D; Kattre N; Nowak J; Bentele M; Keisker M; Dahlke J; Zimmermann K; Sauer M; Heuser M; Schambach A
    Viruses; 2021 Jul; 13(7):. PubMed ID: 34372571
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.