BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 35269588)

  • 1. Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.
    Martínez-Iglesias O; Naidoo V; Carrera I; Cacabelos R
    Int J Mol Sci; 2022 Feb; 23(5):. PubMed ID: 35269588
    [TBL] [Abstract][Full Text] [Related]  

  • 2. COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.
    Wang H; Dey D; Carrera I; Minond D; Bianchi E; Xu S; Lakshmana MK
    J Biol Chem; 2013 Sep; 288(37):26668-77. PubMed ID: 23926111
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor
    Andrew RJ; De Rossi P; Nguyen P; Kowalski HR; Recupero AJ; Guerbette T; Krause SV; Rice RC; Laury-Kleintop L; Wagner SL; Thinakaran G
    J Biol Chem; 2019 Mar; 294(12):4477-4487. PubMed ID: 30692199
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice.
    Kapadia M; Mian MF; Michalski B; Azam AB; Ma D; Salwierz P; Christopher A; Rosa E; Zovkic IB; Forsythe P; Fahnestock M; Sakic B
    J Alzheimers Dis; 2018; 63(3):1191-1205. PubMed ID: 29710702
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques.
    Zhou FQ; Jiang J; Griffith CM; Patrylo PR; Cai H; Chu Y; Yan XX
    Alzheimers Res Ther; 2018 Apr; 10(1):40. PubMed ID: 29690919
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.
    Bhattacharyya R; Teves CAF; Long A; Hofert M; Tanzi RE
    Sci Rep; 2022 Mar; 12(1):3486. PubMed ID: 35241726
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular Genetics of Early- and Late-Onset Alzheimer's Disease.
    Uddin MS; Hasana S; Hossain MF; Islam MS; Behl T; Perveen A; Hafeez A; Ashraf GM
    Curr Gene Ther; 2021; 21(1):43-52. PubMed ID: 33231156
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models.
    De Rossi P; Andrew RJ; Musial TF; Buggia-Prevot V; Xu G; Ponnusamy M; Ly H; Krause SV; Rice RC; de l'Estoile V; Valin T; Salem S; Despa F; Borchelt DR; Bindokas VP; Nicholson DA; Thinakaran G
    Brain Pathol; 2019 Jul; 29(4):485-501. PubMed ID: 30506549
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.
    Soler-López M; Zanzoni A; Lluís R; Stelzl U; Aloy P
    Genome Res; 2011 Mar; 21(3):364-76. PubMed ID: 21163940
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Abundance of Aβ₅-x like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer's disease.
    Guzmán EA; Bouter Y; Richard BC; Lannfelt L; Ingelsson M; Paetau A; Verkkoniemi-Ahola A; Wirths O; Bayer TA
    Mol Neurodegener; 2014 Apr; 9():13. PubMed ID: 24694184
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.
    Readhead B; Haure-Mirande JV; Zhang B; Haroutunian V; Gandy S; Schadt EE; Dudley JT; Ehrlich ME
    Mol Psychiatry; 2016 Aug; 21(8):1099-111. PubMed ID: 26552589
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.
    España J; Giménez-Llort L; Valero J; Miñano A; Rábano A; Rodriguez-Alvarez J; LaFerla FM; Saura CA
    Biol Psychiatry; 2010 Mar; 67(6):513-21. PubMed ID: 19664757
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alzheimer's disease BIN1 coding variants increase intracellular Aβ levels by interfering with BACE1 recycling.
    Perdigão C; Barata MA; Burrinha T; Guimas Almeida C
    J Biol Chem; 2021 Sep; 297(3):101056. PubMed ID: 34375641
    [TBL] [Abstract][Full Text] [Related]  

  • 14. L-3-n-butylphthalide improves cognitive impairment and reduces amyloid-beta in a transgenic model of Alzheimer's disease.
    Peng Y; Sun J; Hon S; Nylander AN; Xia W; Feng Y; Wang X; Lemere CA
    J Neurosci; 2010 Jun; 30(24):8180-9. PubMed ID: 20554868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone deacetylase-3 regulates the expression of the amyloid precursor protein and its inhibition promotes neuroregenerative pathways in Alzheimer's disease models.
    Davis N; Taylor B; Abelleira-Hervas L; Karimian-Marnani N; Aleksynas R; Syed N; Di Giovanni S; Palmisano I; Sastre M
    FASEB J; 2024 May; 38(10):e23659. PubMed ID: 38733301
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bridging Integrator 1 (BIN1) Genotypes Mediate Alzheimer's Disease Risk by Altering Neuronal Degeneration.
    Wang HF; Wan Y; Hao XK; Cao L; Zhu XC; Jiang T; Tan MS; Tan L; Zhang DQ; Tan L; Yu JT;
    J Alzheimers Dis; 2016 Mar; 52(1):179-90. PubMed ID: 27003210
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amyloid-β protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer's disease.
    Rolyan H; Feike AC; Upadhaya AR; Waha A; Van Dooren T; Haass C; Birkenmeier G; Pietrzik CU; Van Leuven F; Thal DR
    J Neural Transm (Vienna); 2011 May; 118(5):699-712. PubMed ID: 21210284
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
    Sakae N; Liu CC; Shinohara M; Frisch-Daiello J; Ma L; Yamazaki Y; Tachibana M; Younkin L; Kurti A; Carrasquillo MM; Zou F; Sevlever D; Bisceglio G; Gan M; Fol R; Knight P; Wang M; Han X; Fryer JD; Fitzgerald ML; Ohyagi Y; Younkin SG; Bu G; Kanekiyo T
    J Neurosci; 2016 Mar; 36(13):3848-59. PubMed ID: 27030769
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.
    Martiskainen H; Viswanathan J; Nykänen NP; Kurki M; Helisalmi S; Natunen T; Sarajärvi T; Kurkinen KM; Pursiheimo JP; Rauramaa T; Alafuzoff I; Jääskeläinen JE; Leinonen V; Soininen H; Haapasalo A; Huttunen HJ; Hiltunen M
    Neurobiol Aging; 2015 Feb; 36(2):1221.e15-28. PubMed ID: 25281018
    [TBL] [Abstract][Full Text] [Related]  

  • 20. X11alpha haploinsufficiency enhances Abeta amyloid deposition in Alzheimer's disease transgenic mice.
    Saluja I; Paulson H; Gupta A; Turner RS
    Neurobiol Dis; 2009 Oct; 36(1):162-8. PubMed ID: 19631749
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.