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9. Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia. Kim E; Napierala M; Dent SY Nucleic Acids Res; 2011 Oct; 39(19):8366-77. PubMed ID: 21745819 [TBL] [Abstract][Full Text] [Related]
10. Correlation between frataxin expression and contractility revealed by in vitro Friedreich's ataxia cardiac tissue models engineered from human pluripotent stem cells. Wong AO; Wong G; Shen M; Chow MZ; Tse WW; Gurung B; Mak SY; Lieu DK; Costa KD; Chan CW; Martelli A; Nabhan JF; Li RA Stem Cell Res Ther; 2019 Jul; 10(1):203. PubMed ID: 31286988 [TBL] [Abstract][Full Text] [Related]
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12. Generation and characterization of two human iPSC lines, IGIBi014-A and IGIBi015-A, from Friedreich's ataxia (FRDA) patients with pathogenic (GAA/TTC)n repeat expansion in first intron of the Frataxin (FXN) gene. Ahmad I; Kapoor H; Kumar Srivastava A; Faruq M Stem Cell Res; 2024 Feb; 74():103289. PubMed ID: 38141359 [TBL] [Abstract][Full Text] [Related]
13. Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instability. Ku S; Soragni E; Campau E; Thomas EA; Altun G; Laurent LC; Loring JF; Napierala M; Gottesfeld JM Cell Stem Cell; 2010 Nov; 7(5):631-7. PubMed ID: 21040903 [TBL] [Abstract][Full Text] [Related]
14. Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures. Lai JI; Nachun D; Petrosyan L; Throesch B; Campau E; Gao F; Baldwin KK; Coppola G; Gottesfeld JM; Soragni E J Biol Chem; 2019 Feb; 294(6):1846-1859. PubMed ID: 30552117 [TBL] [Abstract][Full Text] [Related]
15. Epigenetics in Friedreich's Ataxia: Challenges and Opportunities for Therapy. Sandi C; Al-Mahdawi S; Pook MA Genet Res Int; 2013; 2013():852080. PubMed ID: 23533785 [TBL] [Abstract][Full Text] [Related]
16. Genome-Engineering Tools to Establish Accurate Reporter Cell Lines That Enable Identification of Therapeutic Strategies to Treat Friedreich's Ataxia. Villaseñor R; Miraglia L; Romero A; Tu B; Punga T; Knuckles P; Duss S; Orth T; Bühler M J Biomol Screen; 2015 Jul; 20(6):760-7. PubMed ID: 25616511 [TBL] [Abstract][Full Text] [Related]
17. Defining Transcription Regulatory Elements in the Human Frataxin Gene: Implications for Gene Therapy. Li J; Li Y; Wang J; Gonzalez TJ; Asokan A; Napierala JS; Napierala M Hum Gene Ther; 2020 Aug; 31(15-16):839-851. PubMed ID: 32527155 [TBL] [Abstract][Full Text] [Related]
18. Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers. Napierala JS; Li Y; Lu Y; Lin K; Hauser LA; Lynch DR; Napierala M Dis Model Mech; 2017 Nov; 10(11):1353-1369. PubMed ID: 29125828 [TBL] [Abstract][Full Text] [Related]
19. Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3. Chan PK; Torres R; Yandim C; Law PP; Khadayate S; Mauri M; Grosan C; Chapman-Rothe N; Giunti P; Pook M; Festenstein R Hum Mol Genet; 2013 Jul; 22(13):2662-75. PubMed ID: 23474817 [TBL] [Abstract][Full Text] [Related]
20. Friedreich's ataxia--a case of aberrant transcription termination? Butler JS; Napierala M Transcription; 2015; 6(2):33-6. PubMed ID: 25831023 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]