149 related articles for article (PubMed ID: 35285625)
1. Evidence Supporting Substrate Channeling between Domains of Human PAICS: A Time-Course Analysis of
Shon H; Matveeva EA; Jull EC; Hu Y; Coupet TA; Lee YS
Biochemistry; 2022 Apr; 61(7):575-582. PubMed ID: 35285625
[TBL] [Abstract][Full Text] [Related]
2. Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
Škerlová J; Unterlass J; Göttmann M; Marttila P; Homan E; Helleday T; Jemth AS; Stenmark P
J Biol Chem; 2020 Aug; 295(33):11656-11668. PubMed ID: 32571877
[TBL] [Abstract][Full Text] [Related]
3. Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis.
Li SX; Tong YP; Xie XC; Wang QH; Zhou HN; Han Y; Zhang ZY; Gao W; Li SG; Zhang XC; Bi RC
J Mol Biol; 2007 Mar; 366(5):1603-14. PubMed ID: 17224163
[TBL] [Abstract][Full Text] [Related]
4. [Substrate specificity of phosphoribosyl-aminoimidazole-succinocarboxamide synthetase (SAICAR-synthetase) from Saccharomyces cerevisiae yeast].
Alenin VV; Ostanin KV; Kostikova TR; Domkin VD; Zubova VA; Smirnov MN
Biokhimiia; 1992 Jun; 57(6):845-55. PubMed ID: 1420588
[TBL] [Abstract][Full Text] [Related]
5. Nucleotide complexes of Escherichia coli phosphoribosylaminoimidazole succinocarboxamide synthetase.
Ginder ND; Binkowski DJ; Fromm HJ; Honzatko RB
J Biol Chem; 2006 Jul; 281(30):20680-20688. PubMed ID: 16687397
[TBL] [Abstract][Full Text] [Related]
6. Multienzyme interactions of the de novo purine biosynthetic protein PAICS facilitate purinosome formation and metabolic channeling.
He J; Zou LN; Pareek V; Benkovic SJ
J Biol Chem; 2022 May; 298(5):101853. PubMed ID: 35331738
[TBL] [Abstract][Full Text] [Related]
7. PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
Pelet A; Skopova V; Steuerwald U; Baresova V; Zarhrate M; Plaza JM; Hnizda A; Krijt M; Souckova O; Wibrand F; Andorsdóttir G; Joensen F; Sedlak D; Bleyer AJ; Kmoch S; Lyonnet S; Zikanova M
Hum Mol Genet; 2019 Nov; 28(22):3805-3814. PubMed ID: 31600779
[TBL] [Abstract][Full Text] [Related]
8. Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders.
Duval N; Luhrs K; Wilkinson TG; Baresova V; Skopova V; Kmoch S; Vacano GN; Zikanova M; Patterson D
Mol Genet Metab; 2013 Mar; 108(3):178-189. PubMed ID: 23394948
[TBL] [Abstract][Full Text] [Related]
9. Reaction Mechanism of Human PAICS Elucidated by Quantum Chemical Calculations.
Prejanò M; Škerlová J; Stenmark P; Himo F
J Am Chem Soc; 2022 Aug; 144(31):14258-14268. PubMed ID: 35914774
[TBL] [Abstract][Full Text] [Related]
10. Mechanism of action of Escherichia coli phosphoribosylaminoimidazolesuccinocarboxamide synthetase.
Nelson SW; Binkowski DJ; Honzatko RB; Fromm HJ
Biochemistry; 2005 Jan; 44(2):766-74. PubMed ID: 15641804
[TBL] [Abstract][Full Text] [Related]
11. Evidence for the direct transfer of the carboxylate of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to generate 4-carboxy-5-aminoimidazole ribonucleotide catalyzed by Escherichia coli PurE, an N5-CAIR mutase.
Meyer E; Kappock TJ; Osuji C; Stubbe J
Biochemistry; 1999 Mar; 38(10):3012-8. PubMed ID: 10074353
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of the invertebrate bifunctional purine biosynthesis enzyme PAICS at 2.8 Å resolution.
Taschner M; Basquin J; Benda C; Lorentzen E
Proteins; 2013 Aug; 81(8):1473-8. PubMed ID: 23553965
[TBL] [Abstract][Full Text] [Related]
13. Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer.
Goswami MT; Chen G; Chakravarthi BV; Pathi SS; Anand SK; Carskadon SL; Giordano TJ; Chinnaiyan AM; Thomas DG; Palanisamy N; Beer DG; Varambally S
Oncotarget; 2015 Sep; 6(27):23445-61. PubMed ID: 26140362
[TBL] [Abstract][Full Text] [Related]
14. Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development.
Ng A; Uribe RA; Yieh L; Nuckels R; Gross JM
Development; 2009 Aug; 136(15):2601-11. PubMed ID: 19570845
[TBL] [Abstract][Full Text] [Related]
15. Catalytic pathway, substrate binding and stability in SAICAR synthetase: A structure and molecular dynamics study.
Manjunath K; Jeyakanthan J; Sekar K
J Struct Biol; 2015 Jul; 191(1):22-31. PubMed ID: 26072057
[TBL] [Abstract][Full Text] [Related]
16. PAICS as a potential target for cancer therapy linking purine biosynthesis to cancer progression.
Huo A; Xiong X
Life Sci; 2023 Oct; 331():122070. PubMed ID: 37673296
[TBL] [Abstract][Full Text] [Related]
17. Treponema denticola PurE Is a bacterial AIR carboxylase.
Tranchimand S; Starks CM; Mathews II; Hockings SC; Kappock TJ
Biochemistry; 2011 May; 50(21):4623-37. PubMed ID: 21548610
[TBL] [Abstract][Full Text] [Related]
18. Isatins Inhibit N
Streeter CC; Lin Q; Firestine SM
Biochemistry; 2019 Apr; 58(17):2260-2268. PubMed ID: 30964980
[TBL] [Abstract][Full Text] [Related]
19. Structural analysis of the active site geometry of N5-carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.
Thoden JB; Holden HM; Firestine SM
Biochemistry; 2008 Dec; 47(50):13346-53. PubMed ID: 19053251
[TBL] [Abstract][Full Text] [Related]
20. Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
Meng M; Chen Y; Jia J; Li L; Yang S
Biol Res; 2018 Aug; 51(1):24. PubMed ID: 30097015
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]