153 related articles for article (PubMed ID: 35294522)
1. Phase Ib/II Trial of Ribociclib in Combination with Binimetinib in Patients with NRAS-mutant Melanoma.
Schuler M; Zimmer L; Kim KB; Sosman JA; Ascierto PA; Postow MA; De Vos FYFL; van Herpen CML; Carlino MS; Johnson DB; Berking C; Reddy MB; Harney AS; Berlin JD; Amaria RN
Clin Cancer Res; 2022 Jul; 28(14):3002-3010. PubMed ID: 35294522
[TBL] [Abstract][Full Text] [Related]
2. Binimetinib versus dacarbazine in patients with advanced NRAS-mutant melanoma (NEMO): a multicentre, open-label, randomised, phase 3 trial.
Dummer R; Schadendorf D; Ascierto PA; Arance A; Dutriaux C; Di Giacomo AM; Rutkowski P; Del Vecchio M; Gutzmer R; Mandala M; Thomas L; Demidov L; Garbe C; Hogg D; Liszkay G; Queirolo P; Wasserman E; Ford J; Weill M; Sirulnik LA; Jehl V; Bozón V; Long GV; Flaherty K
Lancet Oncol; 2017 Apr; 18(4):435-445. PubMed ID: 28284557
[TBL] [Abstract][Full Text] [Related]
3. War against NRAS-Mutant Melanoma Using Targeted Therapies Remains Challenging.
Moschos SJ
Clin Cancer Res; 2022 Jul; 28(14):2977-2979. PubMed ID: 35587446
[TBL] [Abstract][Full Text] [Related]
4. Phase Ib Study of Combination Therapy with MEK Inhibitor Binimetinib and Phosphatidylinositol 3-Kinase Inhibitor Buparlisib in Patients with Advanced Solid Tumors with RAS/RAF Alterations.
Bardia A; Gounder M; Rodon J; Janku F; Lolkema MP; Stephenson JJ; Bedard PL; Schuler M; Sessa C; LoRusso P; Thomas M; Maacke H; Evans H; Sun Y; Tan DSW
Oncologist; 2020 Jan; 25(1):e160-e169. PubMed ID: 31395751
[TBL] [Abstract][Full Text] [Related]
5. Initial Evidence for the Efficacy of Naporafenib in Combination With Trametinib in
de Braud F; Dooms C; Heist RS; Lebbe C; Wermke M; Gazzah A; Schadendorf D; Rutkowski P; Wolf J; Ascierto PA; Gil-Bazo I; Kato S; Wolodarski M; McKean M; Muñoz Couselo E; Sebastian M; Santoro A; Cooke V; Manganelli L; Wan K; Gaur A; Kim J; Caponigro G; Couillebault XM; Evans H; Campbell CD; Basu S; Moschetta M; Daud A
J Clin Oncol; 2023 May; 41(14):2651-2660. PubMed ID: 36947734
[TBL] [Abstract][Full Text] [Related]
6. Binimetinib for the treatment of NRAS-mutant melanoma.
Queirolo P; Spagnolo F
Expert Rev Anticancer Ther; 2017 Nov; 17(11):985-990. PubMed ID: 28851243
[TBL] [Abstract][Full Text] [Related]
7. First-in-human phase I dose-escalation and dose-expansion trial of the selective MEK inhibitor HL-085 in patients with advanced melanoma harboring NRAS mutations.
Wang X; Luo Z; Chen J; Chen Y; Ji D; Fan L; Chen L; Zhao Q; Hu P; Sun P; Jia Z; Guo J; Si L
BMC Med; 2023 Jan; 21(1):2. PubMed ID: 36600247
[TBL] [Abstract][Full Text] [Related]
8. A Phase Ib/II Study of the BRAF Inhibitor Encorafenib Plus the MEK Inhibitor Binimetinib in Patients with
Sullivan RJ; Weber J; Patel S; Dummer R; Carlino MS; Tan DSW; Lebbé C; Siena S; Elez E; Wollenberg L; Pickard MD; Sandor V; Ascierto PA
Clin Cancer Res; 2020 Oct; 26(19):5102-5112. PubMed ID: 32669376
[TBL] [Abstract][Full Text] [Related]
9. Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial.
Dummer R; Ascierto PA; Gogas HJ; Arance A; Mandala M; Liszkay G; Garbe C; Schadendorf D; Krajsova I; Gutzmer R; Chiarion Sileni V; Dutriaux C; de Groot JWB; Yamazaki N; Loquai C; Moutouh-de Parseval LA; Pickard MD; Sandor V; Robert C; Flaherty KT
Lancet Oncol; 2018 Oct; 19(10):1315-1327. PubMed ID: 30219628
[TBL] [Abstract][Full Text] [Related]
10. Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial.
Dummer R; Ascierto PA; Gogas HJ; Arance A; Mandala M; Liszkay G; Garbe C; Schadendorf D; Krajsova I; Gutzmer R; Chiarion-Sileni V; Dutriaux C; de Groot JWB; Yamazaki N; Loquai C; Moutouh-de Parseval LA; Pickard MD; Sandor V; Robert C; Flaherty KT
Lancet Oncol; 2018 May; 19(5):603-615. PubMed ID: 29573941
[TBL] [Abstract][Full Text] [Related]
11. A review of binimetinib for the treatment of mutant cutaneous melanoma.
Koelblinger P; Dornbierer J; Dummer R
Future Oncol; 2017 Aug; 13(20):1755-1766. PubMed ID: 28587477
[TBL] [Abstract][Full Text] [Related]
12. An overview of binimetinib for the treatment of melanoma.
Specenier P
Expert Opin Pharmacother; 2020 May; 21(7):747-754. PubMed ID: 32100585
[TBL] [Abstract][Full Text] [Related]
13. Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced
van Herpen CML; Agarwala SS; Hauschild A; Berking C; Beck JT; Schadendorf D; Jansen R; Queirolo P; Ascierto PA; Blank CU; Heinrich MC; Pal RR; Derti A; Antona V; Nauwelaerts H; Zubel A; Dummer R
Oncotarget; 2019 Mar; 10(19):1850-1859. PubMed ID: 30956763
[No Abstract] [Full Text] [Related]
14. Differential Outcomes in Codon 12/13 and Codon 61
Cleary JM; Wang V; Heist RS; Kopetz ES; Mitchell EP; Zwiebel JA; Kapner KS; Chen HX; Li S; Gray RJ; McShane LM; Rubinstein LV; Patton DR; Meric-Bernstam F; Dillmon MS; Williams PM; Hamilton SR; Conley BA; Aguirre AJ; O'Dwyer PJ; Harris LN; Arteaga CL; Chen AP; Flaherty KT
Clin Cancer Res; 2021 Jun; 27(11):2996-3004. PubMed ID: 33637626
[TBL] [Abstract][Full Text] [Related]
15. Phase Ib/II study of ceritinib in combination with ribociclib in patients with ALK-rearranged non-small cell lung cancer.
Santoro A; Su WC; Navarro A; Simonelli M; Ch Yang J; Ardizzoni A; Barlesi F; Hyoung Kang J; DiDominick S; Abdelhady A; Chen X; Stammberger U; Felip E
Lung Cancer; 2022 Apr; 166():170-177. PubMed ID: 35298959
[TBL] [Abstract][Full Text] [Related]
16. A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors.
Geoerger B; Bourdeaut F; DuBois SG; Fischer M; Geller JI; Gottardo NG; Marabelle A; Pearson ADJ; Modak S; Cash T; Robinson GW; Motta M; Matano A; Bhansali SG; Dobson JR; Parasuraman S; Chi SN
Clin Cancer Res; 2017 May; 23(10):2433-2441. PubMed ID: 28432176
[No Abstract] [Full Text] [Related]
17. Long-Term Response to Intermittent Binimetinib in Patients with NRAS-Mutant Melanoma.
Matter AV; Micaletto S; Urner-Bloch U; Dummer R; Goldinger SM
Oncologist; 2020 Nov; 25(11):e1593-e1597. PubMed ID: 32886824
[TBL] [Abstract][Full Text] [Related]
18. Phase Ib Study of Ribociclib plus Fulvestrant and Ribociclib plus Fulvestrant plus PI3K Inhibitor (Alpelisib or Buparlisib) for HR
Tolaney SM; Im YH; Calvo E; Lu YS; Hamilton E; Forero-Torres A; Bachelot T; Maur M; Fasolo A; Tiedt R; Nardi L; Stammberger U; Abdelhady AM; Ruan S; Lee SC
Clin Cancer Res; 2021 Jan; 27(2):418-428. PubMed ID: 32887722
[TBL] [Abstract][Full Text] [Related]
19. Treatment of NRAS-mutant melanoma.
Johnson DB; Puzanov I
Curr Treat Options Oncol; 2015 Apr; 16(4):15. PubMed ID: 25796376
[TBL] [Abstract][Full Text] [Related]
20. Exploring the In Vitro and In Vivo Therapeutic Potential of BRAF and MEK Inhibitor Combination in NRAS-Mutated Melanoma.
Niessner H; Hüsch A; Kosnopfel C; Meinhardt M; Westphal D; Meier F; Schilling B; Sinnberg T
Cancers (Basel); 2023 Nov; 15(23):. PubMed ID: 38067230
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
